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QUOTE FOR TUESDAY:

“Dialysis is a procedure that can help patients with end stage renal disease to increase quantity and quality of life. However, there are several inherent risks associated with dialysis, which are more profound in patients at risk of complications, such as the elderly or those with other concurrent health conditions.

Typically, the kidneys are responsible for the removal of surplus fluid and for turning excess products into urine, which is then excreted. However, in those with impairments in kidney function, dialysis is often required. Dialysis is a medical procedure that assists in the functions usually carried out by the kidneys in those with poorly functioning kidneys, such as people with renal disease.

Without dialysis, those with kidney issues may experience a toxic build-up of fluid and waste bi-products that can have serious health implications, including death.  Therefore, dialysis enables such individuals to have an improved quality of life.”

News Medical Life Sciences (Benefits and Disadvantages of Dialysis)

Pros and Cons to Hemodialysis and Peritoneal Dialysis.

                 

PERITONEAL DIALYSIS    VS      HEMODIALYSIS

There is not always a simple easy answer for a patient that has chronic renal disease regarding which choice or option of dialysis that is best for him or her ; so let’s investigate the options & know you can always change the choice of dialysis you initially go on.  But remember you are going from a tube placed in your circulatory system to a tube now in your abdomen or visa versa (depending on what your first choice of dialysis was) and that both tubes take time to be ideally ready and final for dialysis after inserted.  So definitely take consideration in your choice both for your body and time it takes to allow the tube (especially in hemodialysis) in getting at its optimal level or state in being used:

  Advantages Limitations
Peritoneal Dialysis ·Flexible lifestyle and independence.

-Time commitment: usually less than 10 hrs per week

-Time allotment: as per patient convenience

-No needles

-Simple techniques: easy learning

-Continuous therapy: minimal fluctuation of symptoms

-Once a month clinic, so no need to travel repeatedly

-Easy personal travel, pack bags and go

-Can use APD: connect at night and go to sleep

Limitations are you need to weave this into lifestyle

-Abdominal catheter

-Does have passive sugar intake, so need to watch for weight gain

-Needs storage space of around half a closet (supplies)

Home Hemodialysis -Flexible lifestyle and independence

-Time commitment: based on therapy ~ 22 hours a week

-Time allotment: at patient convenience

-5-6 times a week so less symptomatic fluctuations

-Much higher freedom in dietary and fluid intake

-May eliminate the need for BP and some of the other medications

-Easy to travel with, pack and go..

-Needs a caregiver at least for the duration of dialysis 5-6 times a week

-Higher commitment compared to hemodialysis

-Need to weave into lifestyle

-Needs storage space of around half a closet

-Does need AVF creation and needle access

In Center Hemodialysis -Dialysis done at clinic by dialysis technicians and nurses  

-Rigid schedule, limited flexibility

-Time commitment: ~20 hours a week

-Time allotment: no flexibility, as per dialysis unit

-Need prior authorization and arrangement for travel

-Cannot travel to region not having dialysis clinic

-Significant fluctuation of symptoms

-Does need AVF creation and needle access

-Need transportation arrangements

 

More than 1/2 a million patients in USA suffer from stage V CKD commonly referred to as Renal Failure (or End Stage Renal Disease (ESRD)) with nearly similar number of patients suffering with the pre-dialysis, stage IV CKD. The management of ESRD involves either replacement of the lost kidney function through the kidney transplantation, or clearing body of the accumulating toxins through maintenance dialysis. Unfortunately, kidney transplantation is not a viable option for a majority of ESRD patients due to a limited availability of donor organs, further compounded by the fact that many of the dialysis patients are medically unsuitable for transplantation. Thus, maintenance dialysis forms mainstay of the treatment for this large majority of the ESRD patients.

  1.  Peritoneal Dialysis (PD): This has been argued as one of the simplest form of dialysis with limited life style interruptions and high degree of freedom. In this form of dialysis a synthetic tube is placed in the abdominal cavity which then allows dialysis by exchange of dialysis fluid at regular intervals. It can be tailored to individual needs so that the patient can perform this at night while asleep with the help of a small machine called “Cycler” or during daytime by performing around four manual exchanges, each lasting around 15-30 minutes. Because of its simplicity, PD is many times a chosen modality for persons with busy lifestyle, active family responsibilities and significant time constraints.
  2. Home Hemodialysis (HHD): Advances in dialysis technologies in recent times has highly simplified the above-mentioned form of hemodialysis allowing it to be performed in the comforts of patients’ home. Development of smaller dialysis machine that can be placed on a nightstand; and simpler blood tubing and dialyzer connections, has resulted in increasing number of patients choosing this modality of dialysis to preserve their independence and high functional status. Though the typical duration for individual patient varies, these form of dialysis can be tailored for an individual’s needs with 5-6 times a week frequency for dialysis with each individual session duration ranging from 3-6 hours. The shorter versions called short daily hemodialysis (SDHD) whereas the longer versions are typically performed at night and thus called nocturnal hemodialysis (NHD). The typical home hemodialysis allows a much higher clearance compared to other forms of dialysis and thus gives greater freedom in terms of dietary restriction and life style choice.
  3. In Center Hemodialysis (HD): Where blood is taken out of the body through a complex set of tubes, run through a filter called dialyzer, cleaned off various impurities, and returned back to the patient. During its passage through the filter, the blood comes in contact with dialysate, which mirrors the body fluid except for the presence of impurities.  This is conventionally performed in dialysis centers across various medical and commercial facilities and typically involves patients receiving dialysis three times a week (either on Monday, Wednesday and Friday OR Tuesday, Thursday and Saturday) with four hour session each time. This is a relatively complex form of dialysis with rigid treatment structure and limited flexibility in terms of patients’ time, mobility and transportation. Additionally, this involves creation and maintenance of vascular access such as dialysis catheter or creation of AV fistula or graft, in either arm or groin to access high flows of blood needed to perform dialysis.

It is uniformly agreed that no single type of dialysis (home Vs In-center dialysis, or Hemo Vs peritoneal dialysis) is superior to others in terms of hard clinical endpoints e.g. mortality or cardiovascular deaths.  However, home dialysis modalities (both PD and HHD) provide significant advantages in multiple outcome parameters important to the management of patients with ESRD namely quality of life, freedom of travel, greater liberty from dietary restrictions, preservation of residual kidney function etc.

Historically, analyses of various patient cohorts in US have consistently revealed that; a privileged patient cohort more frequently chooses a home dialysis. This in many circumstances have been reflected by higher use of peritoneal dialysis in patients that are Caucasians, patients with higher education, patient under the care of nephrologists during the pre-ESRD period, patients receiving pre-dialysis education etc. In fact, nearly half of the patients when provided with a comprehensive pre-dialysis education (CPE) opt for home dialysis. Additionally both individual kidney physician surveys and recommendations of various professional medical societies now recommend a higher utilization of home dialysis. Despite these, only a minority of ESRD patients in US are on Home dialysis modalities. Lack of patient awareness due to lack of pre-dialysis education and scarcity of medical experts performing the home dialysis therapies are the two principle reasons for this underutilization of Home dialysis therapies.

Considering these facts, University of Florida and DCI have established a specialized clinic and education set up where a comprehensive pre-dialysis education (CPE) will be provided to the patients with stage IV (pre-dialysis) CKD along with their multispecialty care for various ailments of CKD. This clinic will put a special emphasis on the comprehensive care of CKD patients with special attention towards their dietary needs, their social and pharmacological concerns and their awareness and needs for decision making for their eventual dialysis or transplant therapies.

In conclusion of renal failure and if you are chronic, it’s not always easy to decide which type of treatment is best for you. Your decision depends on your medical condition, lifestyle, and personal likes and dislikes.

**Discuss the pros and cons of each with your health care team. If you start one form of treatment and decide you’d like to try another, talk it over with your doctor. The key is to learn as much as you can about your choices. With that knowledge, you and your doctor will choose a treatment that suits you best.**

I hope this article help you in some small way or more in dealing with your chronic renal failure.  Know your not alone and have many sites and places in giving you direction and support!

  Always do a Comparison of dialysis methods :  Hemodialysis and Peritoneal dialysis:    
What is usually involved            HEMODIALYSIS

  • Before hemodialysis treatments can begin, your doctor will need to create a site where blood can flow in and out of your body.
  • Hemodialysis uses a man-made membrane called a dialyzer to clean your blood. You are connected to the dialyzer by tubes attached to your blood vessels.
  • You will probably go to a hospital or dialysis center on a fairly set schedule. Hemodialysis usually is done 3 days a week and takes 3 to 5 hours a day.
  • You may be able to do dialysis at home. Home hemodialysis requires training for you and at least one other person. Your home may need some changes so that the equipment will work. You may have choices in how often and how long you can have dialysis, such as every day for shorter periods, long nighttime dialysis, or several times a week for 3 to 5 hours a day.
         PERITONEAL DIALYSIS

  • Your will have a catheter placed in your belly (dialysis access) before you begin dialysis.
  • Peritoneal dialysis uses the lining of your belly, which is called the peritoneal membrane, to filter your blood.
  • The process of doing peritoneal dialysis is called an exchange. You will usually complete 4 to 6 exchanges every day.
  • You will be taught how to do your treatment at home, on your own schedule.
Advantages
  • It is most often done by trained health professionals who can watch for any problems.
  • It allows you to be in contact with other people having dialysis, which may give you emotional support.
  • You don’t have to do it yourself, as you do with peritoneal dialysis.
  • You do it for a shorter amount of time and on fewer days each week than peritoneal dialysis.
  • Home hemodialysis can give you more flexibility in when, where, and how long you have dialysis.
  • It gives you more freedom than hemodialysis. It can be done at home or in any clean place. You can do it when you travel. You may be able to do it while you sleep. You can do it by yourself.
  • It doesn’t require as many food and fluid restrictions as hemodialysis.
  • It doesn’t use needles.
Disadvantages
  • It causes you to feel tired on the day of the treatments.
  • It can cause problems such as low blood pressure and blood clots in the dialysis access.
  • It increases your risk of bloodstream infections.
  • Home hemodialysis may require changes to your home. You and a friend will need to complete training.
  • The procedure may be hard for some people to do.
  • It increases your risk for an infection of the lining of the belly, called peritonitis

QUOTE FOR MONDAY:

Breast cancer is the most common cancer among women. So, you may be wondering how to avoid breast cancer.

While there is no guaranteed way to prevent breast cancer, there are ways to reduce your risk.

As a breast medical oncologist, my top advice is to practice breast awareness, follow screening guidelines and tell your doctor if you have a family history of cancer.

Unmodified Risk Factors (factors we can’t control):

Sex Male or Female – Breast cancer is more common in women, although men can also get breast cancer.  At the time of diagnosis, the average age for a male breast cancer patient is 67, versus age 62 for females. The five-year survival rate for male breast cancer is slightly lower than for female breast cancer. In addition, male breast cancer is typically more advanced when it is diagnosed.

Age – Breast cancer usually develops after menopause for women.

Family History – On average, men are usually diagnosed with breast cancer between ages 60 and 70, according to the National Cancer Institute.

Breast cancer runs in families. You may be at a higher risk of breast cancer if you have a first- or second-degree blood relative who has or had breast cancer. A first-degree relative is a parent, sibling or child. A second-degree relative is a grandparent, aunt, uncle, niece, nephew or half-sibling.

Men with a parent, sibling or child with breast cancer have double the risk of breast cancer.

Gene Mutations are abnormal changes in genes. These mutations can be hereditary, which means they are passed down in families.

Race – White women are slightly more likely to develop breast cancer than Black, Hispanic, and Asian women. But Black women are more likely to develop more aggressive, more advanced-stage breast cancer that is diagnosed at a young age.

Breast cancer screening methods depend on your age and risk for breast cancer.  Women at average risk for breast cancer should receive a clinical breast exam every one to three years between ages 25 and 39.  Starting at age 40, women should receive an annual mammogram in addition to their yearly clinical breast exam.”

The University of Texas / MD Anderson Cancer Center

(How to reduce your breast cancer risk | MD Anderson Cancer Center)

 

 

 

 

Part IV Breast Cancer Ways to reduce breast cancer that you can PREVENT IT & how ethnic groups impact cancer!.

 

Cancer seems like a thunder bolt that it all of a sudden hits us from nowhere, like what happened to my Dad that was in 1999 when he was diagnosed with pancreatic cancer with passing on in about 6 months after diagnosed. Than the hit from nowhere makes the patient and significant others suddenly crippled and not prepared for this diagnosis (facing it with little knowledge or in some cases nothing you can do for the patient since its fatal other than support). No wonder why cancer fears society. To top that alone it is costly, debilitating, depressing, and even fatal, like in my father’s case.

Early detection can vastly improve survival figures, that is not just pertaining to breast cancers but to most diseases period. Delaying to seek advice when changes are recognized is a big mistake.

**Here are some general risk factors for cancer & try to prevent having them in your lives or abusing them (moderation – the key to many things that are not used that way in US). Abuse of anything results in disaster.

1.) Smoking (stop period) including chewing tobacco and dipping snuff. Best to stop these period.

The CDC states in 2020, an estimated 12.5% (30.8 million) of U.S. adults currently smoked cigarettes. Current cigarette smoking was defined as smoking ≥100 cigarettes during a lifetime and now smoking cigarettes either every day or some days.5

Lung cancer mainly occurs in older people. Most people diagnosed with lung cancer are 65 or older; a very small number of people diagnosed are younger than 45. The average age of people when diagnosed is about 70.

Lung cancer is by far the leading cause of cancer death , making up almost 25% of all cancer deaths. Each year, more people die of lung cancer than of colon, breast, and prostate cancers combined.

2.) Diets high in fat or low in fiber. Obesity as well is a risk factor for cancer, odds are high that the diet was high in fat even causing the obesity in the first place.                     

3.) Age is over 50 or too much unresolved stress in your life.

4.) Abuse of alcoholism or inadequate amount of vitamins or minerals in your diet.      Exposure to environmental or occupational cancer causing substances (air, water, radiation, disaster like 9/11, or even food).

5.) Too much radiation from various sources (ex. Sun bathing to close to radiation treatments someone is receiving on a oncology unit, simply Sun overexposure).

6.) Fair complexion (pale) or even family history of cancers in the family (highest risk is within the nuclear family having a mother or father or sibling with cancer).

**Most cancers with heredity in the nuclear family including a bad life style puts that individual at higher probability of inheriting or getting that cancer.**

How ethnic groups play a part in breast cancer or any cancer:

Look at ethnicity; take a completely different country in eating alone. Let us look at Japan and their women. They eat a completely different diet than women in the USA. Japanese women have ¼ the amount of breast cancer than American women; is this mainly genetics? When Japanese women move to the great USA they assume our diets and get the same death rates from breast cancer that American women get when diagnosed with it. My eyes see diet in America (fast food=JUNK). Moderation if not completely banded out of your diet = fast food. Americans who eat junk food on a regular basis are looking at abusing fast food as oppose to a treating themselves to junk food now and than (this is what we call moderation).

Breastcancer.org states:

“Among younger women, Black and non-Hispanic Black women have higher rates of breast cancer compared to white and non-Hispanic white women. Among older women, white and non-Hispanic white women have higher rates of breast cancer compared to Black and non-Hispanic Black women.

White women are slightly more likely to develop breast cancer than Black, Hispanic, and Asian women. But Black women are more likely to develop more aggressive, more advanced-stage breast cancer that is diagnosed at a young age.

White women are slightly more likely to develop breast cancer than Black, Hispanic, and Asian women. But Black women are more likely to develop more aggressive, more advanced-stage breast cancer that is diagnosed at a young age. Black women are also more likely to die from breast cancer. Some of these differences in outcomes may be due to less access to mammography and lower quality medical care, as well as various lifestyle patterns (eating habits and weight issues for example) that are more common in some ethnic groups than in others. These factors can be changed and improved.

Still, triple-negative breast cancer, which is more aggressive than other types, is more common in Black women. Triple-negative breast cancer is estrogen-receptor-negative, progesterone-receptor-negative, and HER2-negative. New treatments for triple-negative breast cancer are being studied in clinical trials.”

The CDC states:

What is already known about this topic?  Breast cancer accounts for 30% of all cancers diagnosed in women.

What is added by this report? During 1999–2018, breast cancer incidence among women aged ≥20 years decreased an average of 0.3% per year, decreasing 2.1% per year during 1999–2004 and increasing 0.3% per year during 2004–2018. Incidence increased among start highlightnon-Hispanic Asian or Pacific end highlightIslander women and women aged 20–39 years but decreased among non-Hispanic White women and women aged 50–64 and ≥75 years.

What are the implications for public health practice?  The U.S. Preventive Services Task Force currently recommends biennial mammography screening for women aged 50–74 years. Women aged 20–49 years might benefit from discussing potential breast cancer risk and ways to reduce risk with their health care providers.”

So what do we do at this point America or anywhere else?

We the people of America or anywhere can make the change in controlling many factors in our diet and exercise to control diseases period we have want to make the move and if we did disease decrease in time would be outstanding. In the end it would make our economy better with our insurance overall.

Ending line, this means less disease, less expense, and meaning better coverage (less out of our pockets financially). For this to even get started we the people in the USA have to be willing to alter diets and exercise to a healthy pattern not a junk food frequently diet or sedentary lifestyle. Help make America a better country for all citizens of all ages. Our government surely hasn’t helped us in prevention tactics to lower statistics in showing less breast cancer significantly.

We do have many improvements with cancer treatment going from diagnostic tooling advancement with even drugs and drugs combined, a multitude of radiation methods and advanced surgical techniques. However, with all this due to increased cancer research, the government has yet to push the most important ingredient for cancer prevention. For every 3 dollars spent on cancer research, only one dollar goes spent in the area of prevention. When your government representative speaks of further cancer research you may want to find out is it for prevention or treatment. My vote is prevention before getting diagnosed with it. That is like the government waiting for a bomb to land on the USA before taking measures to prevent it. Why wait for the disaster when it can be prevented completely and no mess to deal with. Makes sense? Sure does to me and many.

Moderation with anything legal and not being abusive to your body, for ex. Alcohol or prescribed drugs, with the other modifiable factors you can change discussed yesterday, it simply takes someone with will power to make the change or one who already is doing the right activities with diet in their life had will power in doing this lifestyle. That is what it takes to prevent breast cancer and many other diseases simple means making changes in your life=willpower which includes a healthy diet, some regular exercising, keeping your weight ideal to your body mass index, and having the yearly physicals or addressing new symptoms by going to your doctor to have him or she evaluate what it is with the treatment for it. Obese? and can’t lose the weight on your own get a MD consult to see what surgery or other options you have to decrease weight.  All it take is WILL POWER of that individual to do the right moves in life not to get cancer!

Instead of getting it wouldn’t you rather PREVENT it. Remember our disease killers in the USA.   Our #1 killer is cardiovascular our #2 killer is cancer in America!

Ways to prevent breast cancer:

  

020414SMcC2244

The BEST way to go is not to ever get the cancer!!! 

FIGHT BREAST CANCER AND EVEN DISEASE OVERALL BY PREVENTION; that is the KEY!!!! 

 

Part VII Pancreatic Cancer: What are the significant risks for getting this disease?

Pancreatic cancer is one of the few types of cancer that haven’t improved in terms of survival rates over the years, according to the Hirshberg Foundation for Pancreatic Cancer Research. In fact, the foundation said the mortality rate is 93-percent within 5-years of diagnosis. And 71-percent will die in first year.  Usually people diagnosed with this disease are told they have 6 months to 1 year survival rate.  There are the few for the many that live longer but know this the major depending factor is also the stage level of cancer your in (I, II, III & IV).  The higher the worse the metastasis.

These stats point to why it’s important to raise awareness about this killer cancer, and to outline some facts and figures. In honor of Pancreatic Cancer Awareness Month in November, here are six things to know, thanks to Jeff Hayward on November 1 informed the world of this information on his blog with facts…

1. Their are Risk Factors

The American Cancer Society says that the average lifetime risk of developing cancer of the pancreas in both men and women is 1 in 65. However, there are certain factors that might make you more likely to face the disease.

Cancer Treatment Centers of America notes that these risk factors include age (most pancreatic cancers form at age-55 or older), gender (males are slightly more likely to develop it), obesity, diabetes, smoking, and more.

2. Heredity

Cancer Treatment Centers of America also notes that about 10-percent of pancreatic cancer cases are thought to be genetic, or passed down from a parent.

These genetic mutations include hereditary breast and ovarian cancer syndrome (BRCA2), familial melanoma (p16), familial pancreatitis (PRSS1), and neurofibromatosis type-1 (NF1), adds the source. Other “inherited syndromes” can raise risks including Lynch syndrome (hereditary nonpolyposis colorectal cancer), Peutz-Jeghers Syndrome, and Von Hippel-Lindau Syndrome.

3. There Were 50,000 Cases 2016 and NOW:

The American Cancer Society estimated in 2023 there were 53,070 new diagnoses of pancreatic cancer this year in the U.S., and sadly it adds that it expected more than 41,000 of those patients to die from it.

According to the Pancreatic Cancer Action Network report, an estimated 66,440 Americans will be diagnosed with pancreatic cancer in 2024, and 51,750 are predicted to die from the disease this year. Pancreatic cancer continues to be the third-leading cause of cancer-related death in men and women combined in the United States and is on track to become the second-leading cause before 2030.

Of those numbers, there were an estimated 27,670 men diagnosed in 2016, compared to an estimated 25,400 diagnoses for women. The death rates are proportionate for both, according to additional statistics from the cancer society.

The American Cancer Society’s estimates for pancreatic cancer in the United States for 2023 are:

  • About 64,050 people (33,130 men and 30,920 women) will be diagnosed with pancreatic cancer.
  • About 50,550 people (26,620 men and 23,930 women) will die of pancreatic cancer.

Pancreatic cancer accounts for about 3% of all cancers in the US and about 7% of all cancer deaths.

It is slightly more common in men than in women.

4. One of Most Prevalent Cancers in the World

The World Cancer Research Fund International notes that pancreatic cancer shares 10th-place in global prevalence with kidney cancer. Worldwide, there were 338,000 cases of pancreatic cancers diagnosed in 2012 alone, notes the source.

Looking at a breakdown of the disease’s age-standardized rates by country, the U.S. comes in 20th at 7.5-cases per 100,000. The top two countries in the world for cancer of the pancreas are Czech Republic (9.7-per 100,000) and Slovakia (9.4-per 100,000).

5. It Often Causes Symptoms When it’s Too Late

Scientific American talks about why this type of cancer is so deadly in a 2011 article making reference to Apple founder Steve Jobs, who died from the cancer.

It notes that patients sometimes don’t seek treatment right away, because symptoms including weight loss, jaundice and abdominal pain don’t begin until the later stages. “They usually start after the tumor is a significant size. By then, chances are, it has metastasized (that is, spread to other parts of the body),” explains the article.

6. There’s More than One Type

The American Cancer Society explains the overwhelmingly common form of this cancer is pancreatic adenocarcinoma, which makes up 95-percent of all cases. These begin in the ducts of the pancreas and sometimes develop from the cells that form pancreatic enzymes, according to the source.

The “other” type of cancer of the pancreas is pancreatic endocrine tumors, otherwise known as neuroendocrine tumors, explains the cancer society. These tumors can be cancerous or benign, and are subdivided into other categories including “functioning NETs” (including gastrinomas, insulinomas and glucagonomas), and “non-functioning NETs” which are actually more likely to cause cancer because they can grow larger before they’re discovered.

Know how it works you have a pancreas medically noted in Anatomy and Physiology as having a head, neck, body and tail.  The location of the cancer can play a major role especially if diagnosed earlier, depending on the location for some.

The head is the widest part of the pancreas. The head of the pancreas is found in the right side of abdomen, nestled in the curve of the duodenum body and tail.  Worse place for pancreas since this allows metastasis faster than other areas of the pancreas.  The head of the pancreas is connected to other body organs and near lymph nodes making it the ideal place for metastasis (spreading) to occur.   Know this in some cases caught early can make a major change in a longer life for some.

The neck is the thin section of the gland between the head and the body of the pancreas.

The body is the middle part of the pancreas between the neck and the tail. The superior mesenteric artery and vein run behind this part of the pancreas.  This is not connected like the head and if caught early results can be better.

The tail is the thin tip of the pancreas in the left side of the abdomen, in close proximity with the spleen. This is the end of the pancreas connected to nothing, no ducts or other tissues or other body glands of the body that put it near by lymph nodes or connected to and best place for area of the cancer especially if it is only in the tail, in most cases, since less chance of spreading the cancer.  Also if only in the tail of pancreas, surgery will entail removal of that part of the organ with chemo a few months and resolved in most cases.  Just follow up visits to your chemo doctor for however long the M.D. directs you.

QUOTE FOR THE WEEKEND:

“Key Statistics & Facts About Breast Cancer In The United States:

  • Breast cancer is the most common cancer in American women, except for skin cancers.1
  • It is estimated that in 2024, approximately 30% of all new female cancer diagnoses will be breast cancer.1
  • On average, every 2 minutes a woman is diagnosed with breast cancer in the United States.1
  • Approximately 66% of breast cancer cases are diagnosed at a localized stage, before cancer has spread outside of the breast, when it is easiest to treat.3
  • The 5-year relative survival rate for cancer diagnosed at the localized stage is 99%.1
  • Approximately 15% of women diagnosed have a family history of breast cancer. Those with a first-degree relative (mother, sister, daughter) with breast cancer are nearly twice as likely to develop breast cancer themselves.4

National Breast Cancer Foundation Inc. (Breast Cancer Facts & Stats 2025 – Incidence, Age, Survival, & More)

Part III Types of unmodified risk factors (risk factors we can’t change) for breast cancer!

Unmodified Risk factors for Breast Cancer and those are factors we can’t change putting us at risk for breast cancer, which are:

DES Exposure

In the 1950s and 1960s, many pregnant women took a synthetic form of estrogen called diethylstilbestrol (DES) to prevent miscarriage. Many of these women’s daughters eventually developed vaginal and cervical cancer at a rate that seemed higher than normal, and studies found that DES exposure was indeed associated with an increased risk of these types of cancer.

Because of the exposure to additional estrogen, women who were exposed to DES in utero also may be at higher risk for breast cancer. A study published in October 2002 found that in women who were 40 years and older, breast cancer risk was in fact increased if a woman had been exposed to DES.

Because DES is a banned substance, people are no longer at risk for new exposures; however, if you know or suspect that your mother or grandmother took DES while pregnant, you should notify your doctor.

Age at Menstruation

A woman’s amount of exposure to estrogen and progesterone during her lifetime is believed to be a risk factor. The longer a woman is exposed, the more likely she is to develop breast cancer. Therefore, if a woman begins menstruation before age 12, she is believed to be at slightly higher risk.

Age at First Birth

It has been observed that women who have their first child after age 29, or who do not have any children, are at slightly higher risk for breast cancer than women who have their first child before age 29. It has been proposed that breast changes during pregnancy may have protective effects against cancer development because risk of breast cancer appears to decrease with each additional childbirth.

It is important to note that evidence suggests the opposite is true for women who have a family history of breast cancer. In other words, women who have a family history of breast cancer are at lower risk if they have no children or have their children at a later age.

Age at Menopause

Women who go through menopause after the age of 54 have a slightly higher risk of breast cancer than women who go through menopause at age 54 or younger. Their higher risk may be related to their higher lifetime exposure to estrogen and progesterone.

Atypical Hyperplasia or Atypia

Either atypical hyperplasia or atypia indicates the growth of abnormal cells in the breast. The diagnosis of atypical hyperplasia can be made from a core biopsy or excisional biopsy, and has been correlated with an increased risk of breast cancer.

The diagnosis of atypia can be made from nipple aspiration, ductal lavage, or fine needle aspiration (FNA), and also indicates an increased breast cancer risk. Although these cells are not yet cancerous, they do raise a woman’s risk of eventually developing breast cancer. While biopsies and FNAs are usually reserved for when there is a current indication that a woman might have breast cancer, nipple aspiration and ductal lavage are methods that may help assess a woman’s future risk of breast cancer.

Breast Density

Studies have consistently shown that higher breast density is linked with increased risk of breast cancer. Research is examining whether breast density may be modifiable by changing women’s hormones or diet. One medication that has been demonstrated to reduce breast density is tamoxifen.

Serum Estradiol Level

Estradiol is the predominant form of estrogen circulating in the body. ‘Serum estradiol’ refers to the amount of estradiol in the blood, so a woman’s level of serum estradiol may be measured with a simple blood test.

In postmenopausal women, higher hormone levels in the blood have been associated with an increased risk of breast cancer.

QUOTE FOR FRIDAY:

Awareness of the facts and statistics surrounding breast cancer in the United States is key in empowering individuals to make informed decisions about their health.

  • “In 2025, an estimated 316,950 new cases of invasive breast cancer will be diagnosed in women in the U.S., as well as 59,080 new cases of non-invasive (in situ) breast cancer.1
  • 1 in 8 women in the United States will be diagnosed with breast cancer in her lifetime.1
  • 2,800 men will be diagnosed with invasive breast cancer.1
  • There are currently over 4 million breast cancer survivors in the United States.1
  • An estimated 42,170 U.S. women will die from breast cancer in 2025.1
  • Risk of breast cancer recurrence depends on the type and staging of the initial breast cancer. Typically, the highest risk of recurrence is during the first few years after treatment and decreases over time.2″

National Breast Cancer Foundation Inc. (Breast Cancer Facts & Stats 2025 – Incidence, Age, Survival, & More)

Part II Breast Cancer Awareness Month-Know the symptoms, if its metastatic or not, the common treatments for it.

 

Know the symptoms of breast cancer are:

CDC says this:

“Different people have different symptoms of breast cancer. Some people do not have any signs or symptoms at all.

Some warning signs of breast cancer are—

  • New lump in the breast or underarm (armpit).
  • Thickening or swelling of part of the breast.
  • Irritation or dimpling of breast skin.
  • Redness or flaky skin in the nipple area or the breast.
  • Pulling in of the nipple or pain in the nipple area.
  • Nipple discharge other than breast milk, including blood.
  • Any change in the size or the shape of the breast.
  • Pain in any area of the breast.”

Is there a link between birth control pills and breast cancer?

A number of older studies suggested that birth control pills slightly increased the risk of breast cancer, especially among younger women. In these studies, however, 10 years after discontinuing birth control pills women’s risk of breast cancer returned to the same level as that of women who never used oral contraceptives. Current evidence does not support an increase in breast cancer with birth control pills.

Be vigilant about breast cancer detection. If you notice any changes in your breasts, such as a new lump or skin changes, consult your doctor. Also, ask your doctor when to begin mammograms and other screenings.

Once you’ve been diagnosed with breast cancer, your doctor works to find out the specifics of your tumor. Using a tissue sample from your breast biopsy or using your tumor if you’ve already undergone surgery, your medical team determines your breast cancer type. This information helps your doctor decide which treatment options are most appropriate for you.  The biopsy helps what’s used to determine your breast cancer type.

Is your cancer invasive or noninvasive?

Whether your cancer is invasive or noninvasive helps your doctor determine whether your cancer may have spread beyond your breast, which treatments are more appropriate for you, and your risk of developing cancer in the same breast or your other breast.

  • Noninvasive (in situ) breast cancer. In situ breast cancer refers to cancer in which the cells have remained within their place of origin — they haven’t spread to breast tissue around the duct or lobule. One type of noninvasive cancer called ductal carcinoma in situ (DCIS) is considered a precancerous lesion. This means that if it were left in the body, DCIS could eventually develop into an invasive cancer. Another type of noninvasive cancer called lobular carcinoma in situ (LCIS) isn’t considered precancerous because it won’t eventually evolve into invasive cancer. LCIS does, however, increase the risk of cancer in both breasts.
  • Invasive breast cancer. Invasive (infiltrating) breast cancers spread outside the membrane that lines a duct or lobule, invading the surrounding tissues. The cancer cells can then travel to other parts of your body, such as the lymph nodes. If your breast cancer is stage I, II, III or IV, you have invasive breast cancer.

In what part of the breast did your cancer begin?

The type of tissue where your breast cancer arises determines how the cancer behaves and what treatments are most effective. Parts of the breast where cancer begins include:

  • Milk ducts. Ductal carcinoma is the most common type of breast cancer. This type of cancer forms in the lining of a milk duct within your breast. The ducts carry breast milk from the lobules, where it’s made, to the nipple.
  • Milk-producing lobules. Lobular carcinoma starts in the lobules of the breast, where breast milk is produced. The lobules are connected to the ducts, which carry breast milk to the nipple.
  • Connective tissues. Rarely breast cancer can begin in the connective tissue that’s made up of muscles, fat and blood vessels. Cancer that begins in the connective tissue is called sarcoma. Examples of sarcomas that can occur in the breast include phyllodes tumor and angiosarcoma.

FYI a complication that can occur with advanced cancer that many of you may be unaware of; bone metastasis.

Bone metastasis occurs when cancer cells spread from their original site to a location in the bone. The most common types of cancer more likely to spread to bone include breast, prostate and lung cancers.

Bone metastasis can occur in any bone, but more commonly occurs in the pelvis and spine. Bone metastasis may be the first sign that you have cancer, or it may occur years after your cancer treatment is completed, ex. Hodgkins Disease.

Signs and symptoms of bone metastasis may include the following:

  • Bone pain (back and pelvic pain are most common)
  • Unexplained broken bones
  • Loss of urine and/or bowel function
  • Weakness in the legs
  • High levels of calcium in the blood (hypercalcemia), which can cause nausea, vomiting and confusion

The most common problem with metastatic bone cancer is pain and fractures. Metastatic bone cancer usually can’t be cured, but instead the goal is to provide pain relief and control further spread. Treatment can make a big difference and may include the following:

  • Medications to repair and build new bone — These medications are similar to those used by people with osteoporosis and can help in building and strengthening your bone.
  • Chemotherapy — Given as a pill or through a vein, used to control and treat cancer that has spread to the bone.
  • Traditional radiation therapy — Radiation is given as external beam therapy to treat the cancer in the bone.
  • Hormone therapy — Medications are used to block hormones (for breast and prostate cancers) that help control the spread of cancer to the bone.
  • Surgery — Used to fix a fracture and stabilize a break from the cancer in the bone.
  • Cryoablation — A special technique that freezes the cancer cells.
  • Radiofrequency ablation — A special technique that heats the cancer cells.
  • Chemoradiation — A form of internal radiation that is given through the vein and travels to the site of bone metastasis and targets the cancer cells.
  • Pain medications — Medications provided with the goal of relieving and controlling pain from bone metastasis.
  • Physical therapy — Exercises may be prescribed to assist in strengthening muscles and providing any assistive devices that may help you (cane, walker, crutches, etc.).

If you’re living with metastatic bone cancer, you may find help and resources from a website called Bone Health in Focus. It was established with partners including BreastCancer.org, the National Lung Cancer Partnership and Us TOO International Prostate Cancer Education & Support Network to offer resources that help patients and caregivers understand more about cancer that has spread to the bone (find the site at www.bonehealthinfocus.com).

Mayo Clinic information on cancer that has spread to the bone can be found at http://www.mayoclinic.org/diseases-conditions/bone-metastasis/basics/definition/con-20035450.

Are you living with cancer that has spread to the bone? Feel free to share your experiences with each other on the this blog striveforgoodhealth.com or on TheMayoclinic.org.

Make the changes in your lifestyles including diet if you want to prevent cancer, live long and have a productive life.

REFERENCE: Mayoclinic.org

Article reviewed 10/18/2022

 

QUOTE FOR THURSDAY:

“Breast cancer can happen when cells in your breast grow out of control. There are different types of breast cancer. The type depends on which cells in your breast turn into cancer.

Breast cancer can start in many parts of the breast. This includes the ducts, the lobules, or the tissue in between.

Most breast cancers affect people who were assigned female at birth. But breast cancer can also happen to people assigned male at birth. This is rare, but it does happen. See our guide to Male Breast Cancer.

Screening exams can help find breast cancer early. This is also called early detection, and it can save your life!”

Memorial Sloan Kettering Cancer Center – MSKCC (Breast Cancer: Signs & Symptoms, Causes & Prevention, Anatomy & More | Memorial Sloan Kettering Cancer Center)