“Sarcoidosis is a condition that causes tiny collections of immune system cells in any part of the body. These tiny collections form red, swollen lumps called granulomas. Granulomas most commonly occur in the lungs and the lymph nodes of the chest. They also can occur in the eyes, skin, heart and other organs.

Experts don’t know the exact cause of sarcoidosis, but it’s likely a mix of genetic and environmental factors. Some people appear to have gene changes that make them more likely to develop sarcoidosis. The condition may then be triggered by bacteria, viruses, dust or chemicals.”

MAYO CLINIC (Sarcoidosis – Symptoms and causes – Mayo Clinic)

Sarcoidosis (pronounced SAR-COY-DOE-SIS) is an inflammatory disease characterized by the formation of granulomas, tiny clumps of inflammatory cells, in one or more organs of the body. When the immune system goes into overdrive and too many of these clumps form, they can interfere with an organ’s structure and function. When left unchecked, chronic inflammation can lead to fibrosis, which is permanent thickening or scarring of organ tissue.

This disorder can affect almost any organ in the body, including the heart, skin, liver, kidneys, brain, sinuses, eyes, muscles, bones, and other areas. Sarcoidosis most commonly targets the lungs and the lymph nodes, which are an important part of the immune system. When it affects the lungs, it is called pulmonary sarcoidosis. Ninety percent or more of people diagnosed with the disease have lung involvement.

Doctors believe sarcoidosis results from the body’s immune system responding to an unknown substance, most likely something inhaled from the air.

Symptoms in general to people affected by this disease sarcoidosis:

For many people, sarcoidosis begins with these symptoms in general:

“More than half of all Americans age 80 or older either have cataracts or have had surgery to remove cataracts, according to the National Eye Institute (NEI).

The Centers for Disease Control and Prevention (CDC) states that cataract is the leading cause of vision loss in the United States, and the leading cause of blindness worldwide. Prevent Blindness has declared June as Cataract Awareness Month to educate the public on risk factors, symptoms, types of cataract, and cataract surgery.

A cataract is a clouding of the eye’s lens which blocks or changes the passage of light into the eye. The lens of the eye is located behind the pupil and the colored iris and is normally transparent. The lens helps to focus images onto the retina – which transmits the images to the brain.”

Prevent Blindness (https://preventblindness.org/cataract-awareness-june-2022/)

Medications that can cause Cataracts:

Certain medications are well-known causes of cataracts, and some drugs can also accelerate their development. Steroid medications – whether pills, injections, or eye drops – are most frequently associated with cataract formation. If you are taking steroid medications to manage a long-term condition, it is important to note any visual changes and to have your ocular health managed by a qualified ophthalmologist. The medications that can cause cataracts include:  Corticosteroids, Eye drops containing steroids, Glaucoma medications, Certain antipsychotics and antidepressants, Certain medications for autoimmune conditions, and Medication to control heart arrhythmia

Signs and Symptoms of Cataracts:

You may not have any symptoms at first, when cataracts are mild. But as cataracts grow, they can cause changes in your vision. For example, you may notice that:

• Your vision is cloudy or blurry
• Colors look faded
• You can’t see well at night
• Lamps, sunlight, or headlights seem too bright
• You see a halo around lights
• You see double (this sometimes goes away as the cataract gets bigger)
• You have to change the prescription for your glasses often

These symptoms can be a sign of other eye problems, too. Be sure to talk to your eye doctor if you have any of these problems.

HOW YOU CAN PREVENT CATARACTS:

Maintaining healthy eating habits can help to prevent cataracts in two ways. First, a good diet will control your weight, thus eliminating one of the significant risk factors. Second, increasing your antioxidant intake can also inhibit the oxidation process. In a 2013 Swedish, researchers observed 30,000 women over age 49, and found that those who consumed the highest amounts of antioxidants had a 13 percent lower chance of developing cataracts than those who consumed the least amounts.

To reduce your risk for cataracts, be sure to eat plenty of foods high in antioxidants.

TREATMENTS FOR CATARACTS:

“Cataract or Cataracts generally do not cause pain, redness or tears. However, there is changes in your vision, that can vary from blurred vision, double vision, ghost images, the sense of a film over the eyes or Lights seem too dim for reading or close-up work, or you are dazzled by strong light or changing eyeglass prescriptions often. The change may not seem to help your vision. You may sometimes notice the cataract in your eye. It may look like a milky or yellowish spot in the pupil (the center of your eye is normally black).

Prevent Blindness America wants to educate the public on cataracts who has declared June as Cataract Awareness Month. The national non-profit group provides free information through its dedicated web page at preventblindness.org/cataract, or via phone at (800) 331-2020.”

Prevent Blindness (https://preventblindness.org/cataract-awareness-month/)

A cataract is a cloudy area in the lens of your eye. Cataracts are very common as you get older. In fact, more than half of all Americans age 80 or older either have cataracts or have had surgery to get rid of cataracts.

At first, you may not notice that you have a cataract. But over time, cataracts can make your vision blurry, hazy, or less colorful. You may have trouble reading or doing other everyday activities.

There are 3 types of Cataracts:

1-Nuclear cataracts, which form in the lens’ nucleus, are the most common type of cataracts. Because opacity develops in the center of the lens, known as the central nucleus, nuclear cataracts interfere with a person’s ability to see objects in the distance. Usually the result of advancing age, nuclear cataracts can take years to develop and often give the nucleus a yellow tint.

2=Cortical cataracts begin at the outer rim of the lens and gradually work toward the central core. Thus, this type of cataract resembles spokes of a wheel. Patients with cortical cataracts often notice problems with glare, or a “halo” effect around lights. They may also experience a disruption of both near and distance vision.

3-Subcapsular cataracts progress the most rapidly. While nuclear cataracts take years to develop, subcapsular cataracts reach an advanced stage within a matter of months. Posterior subcapsular cataracts affect the back of the lens, causing glare and blurriness. This type of cataract is usually seen in patients who suffer from diabetes, extreme nearsightedness or retinitus pigmentosa, as well as among those who take steroid medication.

Obesity is most commonly linked to the development of posterior subcapsular cataracts. According to researchers at Harvard University, individuals with a BMI of 33 had at least a 30 percent greater likelihood of developing cataracts, compared to subjects with a BMI of 23 or below.

**Congenital cataracts exist and refer to cataracts that are present from birth, as well as to those that develop in early childhood. These cataracts can be nuclear, cortical, or subcapsular. Congenital cataracts may be linked to an infection contracted by the mother during pregnancy or to a genetic condition such as Fabry disease, Alport syndrome, or galactosemia. Because clear vision is essential to the development of the child’s eyes and brain, it is important to diagnose congenital cataracts as early as possible.

Most cataracts form as a result of advancing age. Other possible causes of cataracts include environmental factors and certain medications, such as antidepressants. If your medical history or lifestyle increases your risk of developing cataracts, it is important to have your eye health monitored regularly by a qualified ophthalmologist.

Over 50 percent of Americans over the age of 80 have cataracts

RISK FACTORS:

1 Age

Age is the main reason cataracts form. According to the American Academy of Ophthalmology, the eye disease appears in over 22 million Americans over the age of 40. Over 50 percent of Americans over the age of 80 have cataracts. In fact, if we live long enough, nearly all of us will eventually develop this condition. Because the lens of the eye cannot shed old cells naturally, protein that accumulates on the lens gradually builds up over time, progressively obscuring vision by preventing light from reaching the retina.

2 History of Cataracts in the family

3 Ultraviolet Radiation (UVA or UVB)

According to the U.S. Environmental Protection Agency, long-term exposure to ultraviolet radiation, especially UVB rays, can cause changes in pigment that lead to the formation of cataracts. This is especially common in tropical climates, where high concentrations of UV exposure occur year-round. To protect the eyes from sun damage, it is important to wear sunglasses with a high level of UVA/UVB protection.

4 Trauma to the eye

Injury or trauma to the eye increases a patient’s risk of developing cataracts. Individuals who have experienced inflammation in the eye, either post-operatively or as the result of another eye disease, are also more likely to eventually develop cataracts. For instance, iritis is an ocular condition that causes chronic inflammation inside the eye, and is commonly linked to early and rapid cataract formation.

5 Have certain health problems, like diabetes

6 Smoking and Alcohol

Lifestyle habits such as smoking or consuming alcohol are often considered causes of cataracts.

7 Medications

Certain medications are well-known causes of cataracts, and some drugs can also accelerate their development. Steroid medications – whether pills, injections, or eye drops – are most frequently associated with cataract formation. If you are taking steroid medications to manage a long-term condition, it is important to note any visual changes and to have your ocular health managed by a qualified ophthalmologist.

Most cataracts are caused by normal changes in your eyes as you get older.

When you’re young, the lens in your eye is clear. Around age 40, the proteins in t he lens of your eye start to break down and clump together. This clump makes a cloudy area on your lens — or a cataract. Over time, the cataract gets more severe and clouds more of the lens.

“Alzheimer’s disease is the most common cause of dementia. Alzheimer’s disease is the biological process that begins with the appearance of a buildup of proteins in the form of amyloid plaques and neurofibrillary tangles in the brain. This causes brain cells to die over time and the brain to shrink.

About 6.9 million people in the United States age 65 and older live with Alzheimer’s disease. Among them, more than 70% are age 75 and older. Of the more than 55 million people in the world with dementia, 60% to 70% are estimated to have Alzheimer’s disease.

There is no cure for Alzheimer’s disease.”

MAYO CLINIC (Alzheimer’s disease – Symptoms and causes – Mayo Clinic)

Alzheimer’s disease is the most common form of dementia. This progressive brain disease develops slowly but has a huge impact on those who are living with it, their families, and caregivers.

The number of people living with Alzheimer’s disease is growing. The ripple effect is straining families, communities, and the healthcare system, yet talking about the disease on a personal level can be difficult.

FACTS on Alzheimer’s Disease:

“APHASIA (Uh-Fay-Zhuh) is a result of a STROKE or BRAIN INJURY, and affects a person’s ability to communicate. It is important to remember that you are still a competent adult, you know what you want to say, you can make your own decisions and you are not deaf. Aphasia usually comes on suddenly from a stroke or brain injury. But in rare cases it may develop gradually. This is called Primary Progressive Aphasia (PPA). If you have aphasia, you may find it hard to: TALK, LISTEN/UNDERSTAND OTHERS WHEN THEY SPEAK, READ, WRITE, USE NUMBERS AND DO CALCULATIONS.”

National Aphasia Association (What is Aphasia? – The National Aphasia Association)

What is aphasia?

Aphasia is a disorder that results from damage to portions of the brain that are responsible for language. For most people, these areas are on the left side of the brain. Aphasia usually occurs suddenly, often following a stroke or head injury, but it may also develop slowly, as the result of a brain tumor or a progressive neurological disease. The disorder impairs the expression and understanding of language as well as reading and writing. Aphasia may co-occur with speech disorders, such as dysarthria or apraxia of speech, which also result from brain damage.

Who can acquire aphasia?

Most people who have aphasia are middle-aged or older, but anyone can acquire it, including young children. About 1 million people in the United States currently have aphasia, and nearly 180,000 Americans acquire it each year, according to the National Aphasia Association.

What causes aphasia?

Aphasia is caused by damage to one or more of the language areas of the brain. Most often, the cause of the brain injury is a stroke. A stroke occurs when a blood clot or a leaking or burst vessel cuts off blood flow to part of the brain. Brain cells die when they do not receive their normal supply of blood, which carries oxygen and important nutrients. Other causes of brain injury are severe blows to the head, brain tumors, gunshot wounds, brain infections, and progressive neurological disorders, such as Alzheimer’s disease.

What types of aphasia are there?

There are two broad categories of aphasia: 1-fluent and 2-nonfluent, but know there are several types within these groups.  So the 2 main groups of aphasia are as follows:

1- Fluent aphasia

There is damage to the posterior temporal lobe of the brain.

This may result in Wernicke’s aphasia (see figure above), the most common type of fluent aphasia. People with Wernicke’s aphasia may speak in long, complete sentences that have no meaning, adding unnecessary words and even creating made-up words.

For example, someone with Wernicke’s aphasia may say, “You know that smoodle pinkered and that I want to get him round and take care of him like you want before.”

As a result, it is often difficult to follow what the person is trying to say. People with Wernicke’s aphasia are often unaware of their spoken mistakes. Another hallmark of this type of aphasia is difficulty understanding speech.

2- Nonfluent aphasia

The most common type of nonfluent aphasia is Broca’s aphasia (see figure above).

People with Broca’s aphasia have damage that primarily affects the frontal lobe of the brain.  Damage to a discrete part of the brain in the left frontal lobe (Broca’s area) of the language-dominant hemisphere has been shown to significantly affect the use of spontaneous speech and motor speech control. Words may be uttered very slowly and poorly articulated.

They often have right-sided weakness or paralysis of the arm and leg because the frontal lobe is also important for motor movements. People with Broca’s aphasia may understand speech and know what they want to say, but they frequently speak in short phrases that are produced with great effort. They often omit small words, such as “is,” “and” and “the.”

For example, a person with Broca’s aphasia may say, “Walk dog,” meaning, “I will take the dog for a walk,” or “book book two table,” for “There are two books on the table.” People with Broca’s aphasia typically understand the speech of others fairly well. Because of this, they are often aware of their difficulties and can become easily frustrated.

OTHER TYPES OF APHASIA:

– Global aphasia, results from damage to extensive portions of the language areas of the brain. Individuals with global aphasia have severe communication difficulties and may be extremely limited in their ability to speak or comprehend language.  Damage to the language processing centers in the left hemisphere of your brain, including Wernicke’s and Broca’s areas, can cause global aphasia. These two areas are critical for the production and understanding of language.

This is the most severe form of aphasia. It usually involves the following features.

• Loss of fluency. People with global aphasia struggle with the physical act of speaking. People with the most severe forms of this might only make small or isolated sounds, or they might not make any sounds at all (mutism). They also may repeat words or simple phrases over and over (this is a problem with fluency, as they’ll still have trouble repeating back words or phrases you say to them).
• Problems with understanding. People with this struggle to understand what others are saying. They might understand very simple sentences, but the more complex the sentence or phrase, the harder it is to understand.
• Struggle with repetition. Global aphasia affects repetition, meaning a person with it might struggle to repeat back words or phrases you say to them.
• Other symptoms: This kind of aphasia happens with conditions that cause severe brain damage, such as major strokes or head injuries. The damage is usually severe and affects multiple parts of the brain, causing other serious symptoms like one-sided paralysis, blindness and more.

Other forms of aphasia

• Transcortical motor aphasia: This is similar to Broca’s aphasia but usually not as severe. A key difference is that people with this don’t have a problem repeating back phrases or sentences you say to them.
• Transcortical sensory aphasia: This type is similar to Wernicke’s aphasia but usually not as severe. Like with transcortical motor aphasia above, people with this type don’t have a problem repeating back what you say. This type of aphasia is common with degenerative brain conditions like Alzheimer’s disease.
• Conduction aphasia: This type of aphasia affects fluency but not understanding. People with this struggle to pronounce words, especially when trying to repeat something you say to them.
• Mixed transcortical aphasia: This aphasia is like global aphasia, except that people with this can still repeat what people say to them.
• Anomic aphasia: People with this kind of aphasia struggle to find words, especially names of objects or words that describe actions. To get around this problem, they often use several words to explain what they mean or non-specific words like “thing” instead.