Archive | September 2022

QUOTE FOR WEDNESDAY:

“Horner syndrome is also known as Bernard-Horner syndrome or oculosympathetic palsy.  Horner syndrome is a condition that affects the face and eye on one side of the body. It is caused by the disruption of a nerve pathway from the brain to the head and neck.  Typically, signs and symptoms of Horner syndrome include decreased pupil size, a drooping eyelid and decreased sweating on the affected side of the face. Horner syndrome may be the result of another medical problem, such as a stroke, tumor or spinal cord injury. In some cases, no underlying cause can be found.”

MAYO CLINIC

Horner Syndrome!

Signs and Symptoms:

Horner syndrome is a relatively rare disorder characterized by a constricted pupil (miosis), drooping of the upper eyelid (ptosis), absence of sweating of the face (anhidrosis), and sinking of the eyeball into the bony cavity that protects the eye (enophthalmos). These are the four classic signs of the disorder.

The congenital, and more rare, form of Horner syndrome is present at birth but the cause is not known. Most often, Horner syndrome is acquired as a result of some kind of interference with the sympathetic nerves serving the eyes. The underlying causes can vary enormously, from a snake or insect bite to a neck trauma made by a blunt instrument.

The characteristic physical signs and symptoms associated with Horner syndrome usually affect only one side of the face (unilateral). These include drooping upper eyelid; contracted pupil; dryness (lack of sweating) on the same side of the face (ipsilateral) as the affected eye; and retraction of the eyeball.

If the onset of Horner syndrome is before two years of age, the colored portions of the eyes (irises) may be different colors (heterochromia iridis). In most cases, the iris of the affected side lacks color (hypopigmentation).

Causes:

-In most cases, the physical findings or symptoms are associated with Horner syndrome develop due to an interruption of the sympathetic nerve supply to the eye due to a lesion or growth. The lesion develops somewhere along the path from the eye to the region of the brain that controls the sympathetic nervous system (hypothalamus). The sympathetic nervous system (in conjunction with the parasympathetic nervous system) controls many of the involuntary functions of glands, organs, and other parts of the body.

-carotid artery dissection

the development of a tumors which can be in the neck or chest cavity particularly a neuroblastoma and a tumor of the upper part of the lung (Pancoast tumor); the development of a lesion in midbrain, brain stem, upper spinal cord, neck, or eye orbit; inflammation or growths affecting the lymph nodes of the neck; and/or surgery or other forms of trauma to the neck or upper spinal cord.

Risk Factors:

Horner syndrome may result from any one of a variety of factors!

1. Some cases of Horner syndrome it occurs for no apparent reason or unknown cause (idiopathically).

2. In other cases, it could be heridity.

What some clinical researchers have found, they believe the disorder may be inherited as an autosomal dominant genetic trait.

Chromosomes, which are present in the nucleus of human cells, carry the genetic information for each individual. Human body cells normally have 46 chromosomes. Pairs of human chromosomes are numbered from 1 through 22, and the sex chromosomes are designated X and Y. Males have one X and one Y chromosome, and females have two X chromosomes. Each chromosome has a short arm designated “p” and a long arm designated “q”. Chromosomes are further sub-divided into many bands that are numbered. For example, “chromosome 11p13” refers to band 13 on the short arm of chromosome 11. The numbered bands specify the location of the thousands of genes that are present on each chromosome.

Genetic diseases are determined by the combination of genes for a particular trait that are on the chromosomes received from the father and the mother.

All individuals carry a few abnormal genes. Parents who are close relatives (consanguineous) have a higher chance than unrelated parents to both carry the same abnormal gene, which increases the risk to have children with a recessive genetic disorder.

Dominant genetic disorders occur when only a single copy of an abnormal gene is necessary for the appearance of the disease. The abnormal gene can be inherited from either parent, or can be the result of a new mutation (gene change) in the affected individual. The risk of passing the abnormal gene from affected parent to offspring is 50% for each pregnancy regardless of the sex of the resulting child.

 

QUOTE FOR TUESDAY:

High blood cholesterol is one of the major risk factors for heart disease, causing heart attack and stroke.  According to the Centers for Disease Control and Prevention (CDC), heart disease is the number one leading cause of death in the U.S. More than one million Americans have a heart attack each year and about 500,000 die of heart disease.”

Meridien Research (https://meridienresearch.net/september-national-cholesterol-education-month/)

Part II Cholesterol Month: risk factors, what high cholesterol puts you at risk for and how to prevent this from happening!!

  VS

 

Modifiable Risk Factors putting you at risk for high cholesterol that can put you at risk for heart disease are:

High B/P, Diabetes, Low HDL=good cholesterol, High LDL=bad cholesterol, smoking, eating foods high in SATURATED FAT & CHOLESTEROL, harmful use of alcohol, and lack of any activity in your life (your regular routine doesn’t count like work unless your in a job severely active like construction building homes for example 5 days or week or a personal work out trainer 4 to 5 days week).

MAYO CLINIC states Factors Increasing your BAD Cholesterol:

  • Poor diet. Eating saturated fat, found in animal products, and trans fats, found in some commercially baked cookies and crackers and microwave popcorn, can raise your cholesterol level. Foods that are high in cholesterol, such as red meat and full-fat dairy products, will also increase your cholesterol.
  • Obesity.
  • Lack of exercise. Exercise helps boost your body’s HDL, or “good,” cholesterol while increasing the size of the particles that make up your LDL, or “bad,” cholesterol, which makes it less harmful.
  • Smoking.
  • Age. Because your body’s chemistry changes as you age, your risk of high cholesterol climbs. For instance, as you age, your liver becomes less able to remove LDL cholesterol.
  • Diabetes. High blood sugar contributes to higher levels of a dangerous cholesterol called very-low-density lipoprotein (VLDL) and lower HDL cholesterol. High blood sugar also damages the lining of your arteries.

Non-modifiable Risk Factors=4 types only which are factors we can’t control:

1-Heredity (The higher the risk is when the heredity is closer to you in your family tree=Nuclear family–mom, dad, and siblings).

2-Age (Men aged 45y/o or older & Women aged 55 y/o or older)

3-Gender (It may affect your risk, for years heart disease was considered a man’s disease but we now know that heart disease is the leading cause of death for women as well as men. Although men tend to develop coronary artery disease earlier in life, after age 65 the risk of heart disease for both genders is equal.)

4-Race (Heart disease is higher among African Americans, Mexican Americans, American Indians, native Hawaiians, and some Asian Americans compared to Caucasians).

Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease. With high cholesterol, you can develop fatty deposits in your blood vessels. Eventually, these deposits grow, making it difficult for enough blood to flow through your arteries.
High cholesterol can cause:

Too much cholesterol (LDL cholesterol) puts you at risk for heart disease and stroke, two leading causes of death in the United States. High cholesterol has no signs or symptoms, so the only way to know if you have it is to get your cholesterol checked.

WHAT DOES ALL THIS MEAN?  To make this short & simple, from continuous high cholesterol over time, especially with history in your nuclear family puts you at risk for ATHERO-SCLEROSIS = Blockage In Arteries.  This puts at you at risk for a heart attack, stroke (Based on oxygen blocked by high cholesterol causing lack of oxygenated blood (nutrients) to the heart or brain due to high cholesterol build up in arteries supplying the heart and brain.  This is a high risk for MI & CVA).

Now it makes sense?  The answer to prevention or treatment of cardiac disease is changing or modifying your diet, if it’s unhealthy 100% or just partially. The answer includes exercise (from just walking or if you like working out, even better) and if needed medication but your doctor will decide. All these changes can modify your blood lipid profile=cholesterol control, which helps increasing your heart to a better tolerance with activity, stress and simply functioning. Recommended is going to a cardiologist for people diagnosed with heart conditions or your general practitioner with any illness/disease before making changes to help guide you towards the right choices. Your doctor can help you in determining which prevention or treatment plan is best for you.

Foods high in cholesterol=Fast foods, whole fat dairy products-milk/cheese/butter/mayonnaise/ bacon/processed deli meats/salad dressings and shortenings.

The key is to be living a healthy life. This consists of diet, exercise or activity and healthy habits learned and practiced routinely in your life that will help prevent or assist in treating cardiac disease. The better we treat ourselves regarding health the higher the odds we will live a longer   life. There is not just one food to eat or one type of exercise to do or one healthy habit to keep you healthy, there are choices. Wouldn’t you want less disease/illness for yourself and for others throughout the nation including the future generations?  It is all in change and that would be in your diet, activity getting increased and exercise balanced with rest.  Most importantly sticking to it regularly not doing these changes on occasion and that is all in how well you discipline yourself.

FOR MORE INFORMATION:

National Heart Lung and Blood Institute

P.O. Box 30105

Bethesda, MD 20824-0105

QUOTE FOR THE WEEKEND:

“In 2015–2018, nearly 12% of adults age 20 and older had total cholesterol higher than 240 mg/dL, and about 17% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.1

Slightly more than half of U.S. adults (54.5%, or 47 million) who could benefit from cholesterol medicine are currently taking it.2

Nearly 94 million U.S. adults age 20 or older have total cholesterol levels higher than 200 mg/dL. Twenty-eight million adults in the United States have total cholesterol levels higher than 240 mg/dL.1

7% of U.S. children and adolescents ages 6 to 19 have high total cholesterol.1

High cholesterol has no symptoms, so many people don’t know that their cholesterol is too high. A simple blood test can check cholesterol levels.”

Centers for Disease Control and Prevention (CDC) – https://www.cdc.gov/cholesterol/facts.htm

Part I Cholesterol Month: What is cholesterol, its functions for the body, how its measured, what is good versus bad cholesterol?

 

What is cholesterol?

Cholesterol forms in the liver but we also get cholesterol through foods we eat too. It is a waxy substance that has many important functions in the body. It is part of various hormones, the makeup of the walls of your body’s cells, a component of bile, and many other purposes. How the body processes it is very complex. It joins with a protein and forms a package called lipoprotein. These lipoproteins carry cholesterol through the blood.

What is the functions of cholesterol in the body?

In our bodies, cholesterol serves three main purposes:
  • It aids in the production of sex hormones.
  • It’s a building block for human tissues.
  • It assists in bile production in the liver.
  • Its main function is to maintain the integrity and fluidity of cell membranes.  Cholesterol helps to regulate membrane fluidity over the range of physiological temperatures. to serve as a precursor for the synthesis of substances that are vital for the organism including steroid hormones, bile acids, and vitamin D.

How is cholesterol measured?

Cholesterol is measured in metric system units. The LDL’s (low density lipoproteins) have the bad cholesterol. LDL’s are the main source of blockage in the arteries. HDL’s (high density lipoproteins) have the good cholesterol. HDL’s help keep cholesterol from building up in the wall of the arteries.  Which most foods show on their labels how much LDL and HDL cholesterol is in a serving of the food your buying.  If it doesnt’t show the cholesterol levels on the label than don’t buy it unless its a treat once in awhile.

Through Cleveland Clinic they state the normal levels of cholesterol for total. HDL and LDL should be:

A HDL level for women 20 yrs old or higher should be 50mg/dl or greater.

A HDL level for men at 20 years old or older should be 40mg/dl or greater.

A LDL level for women or men at 20 years old or older should be less than 100mg/dl.

A total cholesterol level less than 200mg/dl is considered good. It represents the least risk of heart disease. Above that, your level is borderline high. If you are above 200 your level of cholesterol is high.

In our body we have cholesterol which is a type of fat. In certain foods is cholesterol depending on the food you buy. Your total cholesterol includes LDL (low-density lipoprotein) and HDL (high density lipoprotein) cholesterol. Let’s differentiate the two:

1.  LDL (low density lipoprotein) the bad cholesterol can build up in the arterial walls and form plaque in time.  What does this mean?

That build up in the arteries will reduce blood flow and increase your risk to heart disease, especially eating frequently the wrong foods with high and bad cholesterol over years (Example. coronary artery disease, high blood pressure, and eating like this for years can lead to a heart attack or from s/s arising scarring the person to go to the doctor and find out they have blockages & need surgery. The sign and symptoms arising scarring the person can range from chest pain, and can be radiating down the arms, sweating profusely, weakness/fatigue increases in your life, dizziness, you feel like you’re going to fall or actually due to the fatigue/weakness=low blood pressure due to the blockage or the heart just working too hard in doing its function since the cardiac output is decreased from the blockage) Take one of my dear friends who I have known almost 40 years who was a workaholic 10to14hr/7 days a week for at least 35 years and 2 years ago he had to undergo surgery for a coronary artery blockage bypass for 5 vessels blocked 80% to 100%. He should have been dead already due to a heart attach for such blockage but had a successful bypass done followed by long rehab and got better due to high cholesterol eating, smoking (that both play an impact in plaque & tar build up in the vessels) and he stopped but he also was obese by about 50lbs. and lost 30lbs due to better eating and less beer. This could have been prevented if he changed his diet, watched his weight, and quit smoking years ago but that takes discipline, making sacrifices is all within your hands to allow for healthy habits now (prevention) or later when problems occur (treatment), if caught in time. There is a way out of this happening to you.

2-HDL (high density lipoprotein) the good cholesterol it’s known as.  What does this mean?

Because it is thought to help remove bad cholesterol from the body; if you decide the right foods in the right portions that will have more HDL than LDL in them. Differentiating the 2, now another component to keep in mind is risk factors that can put you at risk for heart disease and your doctor will determine what additional risk factors you have putting you at risk for heart disease. These risk factors can be modifiable (controllable by individuals) or non-modifiable (non-controllable by individuals).  Stayed tune for Part II on cholesterol tomorrow covering all this!

 

QUOTE FOR FRIDAY:

“Reye’s Syndrome, a deadly disease, strikes swiftly and can attack any child, teen, or adult without warning. All body organs are affected with the liver and brain suffering most seriously. While the cause and cure remain unknown, research has established a link between Reye’s Syndrome and the use of aspirin and other salicylate containing medications, over the counter products, and topical use products.

Reye’s Syndrome is a two-phase illness because it is almost always associated with a previous viral infection such as influenza (flu), cold, or chicken pox. Scientists do know that Reye’s Syndrome is not contagious and the cause is unknown. Reye’s Syndrome is often misdiagnosed as encephalitis, meningitis, diabetes, drug overdose, poisoning, Sudden Infant Death Syndrome, or psychiatric illness.”

Reyes Syndrome Foundation (https://www.reyessyndrome.org/blank-1)

 

 

Reye’s Syndrome

Reye’s syndrome is a rare but serious disease that causes swelling in the liver and brain. It can affect people of any age, but it is most often seen in children and teenagers recovering from a virus such as the flu or chickenpox.Studies have found that the main risk factor for Reye’s syndrome is taking aspirin or other related drugs, called salicylates.Because of this, doctors recommend that children and teenagers recovering from viral infections should avoid taking aspirin.

What Causes It?

Doctors don’t fully understand what causes Reye’s syndrome. They do know that some people are prone to get it when they take aspirin for a virus.

Others have a greater chance of getting it if they:

  • Have a disorder that affects how their bodies break down fatty acids
  • Have been exposed to certain toxins, including paint thinners and products to kill insects and weeds

When Reye’s syndrome strikes, cells throughout your body become swollen and build up fats. In turn, your blood sugar levels drop. Ammonia and acid levels in the blood rise. These changes can hit many organs, such as the brain and liver, where severe swelling can occur.

Symptoms

The signs of Reye’s typically appear 3 to 5 days after the start of a viral infection.

In children younger than age 2, early symptoms may include diarrhea and rapid breathing. In older children and teenagers, early symptoms may include ongoing vomiting and unusual sleepinessAs the syndrome goes on, symptoms can become more severe, and may include:

  • Personality changes (more irritable or aggressive)
  • Confusion or hallucinations
  • Weakness or inability to move arms or legs
  • Seizure or convulsions
  • Extreme tiredness
  • Loss of consciousness

Reye’s can be life-threatening. You should call 911 if you see these severe symptoms. Early diagnosis and treatment is crucial.

The syndrome can be mistaken for other conditions, including meningitis (a swelling of membranes covering the brain and spinal cord), a diabetes reaction, or poisoning.

Diagnosis

Doctors don’t have a specific test for Reye’s. They usually do urine and blood tests. They also screen for disorders involving fatty acids.

Other tests may include:

  • Spinal taps (a needle is inserted into a space below the end of the spinal cord to collect fluid)
  • Liver biopsies (a needle is pushed through the abdomen into the liver to get a sample of tissue)
  • Skin biopsies (a doctor scrapes a small skin sample to test)
  • CT or MRI scans (which can also rule out other problems)

Is There a Treatment?

There’s no single treatment that will stop Reye’s syndrome, but doctors can do some things to make sure it is managed. They can also try to prevent more severe symptoms and see that brain swelling is held down. These steps include:

  • Intravenous (IV) fluids that includes glucose and an electrolyte solution may be given through an intravenous (IV) line.
  • Diuretics to help your body get rid of salt and water (and stop swelling)
  • Medications to prevent bleeding
  • Vitamin K, plasma, and platelets (tiny blood cells that help form clots) in instances of liver bleeding
  • Cooling blankets. This intervention helps maintain internal body temperature at a safe level.

 

QUOTE FOR THURSDAY:

“Sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell disease have red blood cells that contain mostly hemoglobin S, an abnormal type of hemoglobin. Sometimes these red blood cells become sickle-shaped (crescent shaped) and have difficulty passing through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can reach that part of the body. Tissue that does not receive a normal blood flow eventually becomes damaged. This is what causes the complications of sickle cell disease.

Hemoglobin is the main substance of the red blood cell. It helps red blood cells carry oxygen from the air in our lungs to all parts of the body. Normal red blood cells contain hemoglobin A. Normal red blood cells that contain hemoglobin A are soft and round and can squeeze through tiny blood tubes (vessels). Normally, red blood cells live for about 120 days before new ones replace them.  People with sickle cell conditions make a different form of hemoglobin A called hemoglobin S (S stands for sickle). Red blood cells containing mostly hemoglobin S do not live as long as normal red blood cells (normally about 16 days).”.

Sickle Cell Disease Organization of America Inc. (https://www.sicklecelldisease.org/sickle-cell-health-and-disease/types/#)

 

QUOTE FOR WEDNESDAY:

“According to the Centers for Disease Control, each year in the United States, approximately 71,500 women are diagnosed with gynecological cancers. Each gynecological cancer has different signs and symptoms, as well as different risk factors. Risk increases with age.”

American Association for Cancer Research

(https://www.aacr.org/patients-caregivers/awareness-months/gynecologic-cancer-awareness-month/)

September is Gynecologic Cancer Awareness Month.