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Part II July UV Safety Month – How to prevent sunburn, types of photosensitivity, health issues that are related to UV radiation, and what Vit D can do for you!

The three types of Ultra Violet radiation are classified according to their wavelength.

They differ in their biological activity and the extent to which they can penetrate the skin. The shorter the wavelength, the more harmful the UV radiation. However, shorter wavelength UV radiation is less able to penetrate the skin.

The Ultra Violet region covers the wavelength range 100-400 nm and is divided into three bands:

  • UVA (315-400 nm)
  • UVB (280-315 nm)
  • UVC (100-280 nm).

Short-wavelength UVC is the most damaging type of UV radiation. However, it is completely filtered by the atmosphere and does not reach the earth’s surface.

Medium-wavelength UVB is very biologically active but cannot penetrate beyond the superficial skin layers. It is responsible for delayed tanning and burning; in addition to these short-term effects it enhances skin ageing and significantly promotes the development of skin cancer. Most solar UVB is filtered by the atmosphere.

The relatively long-wavelength UVA accounts for approximately 95 per cent of the UV radiation reaching the Earth’s surface. It can penetrate into the deeper layers of the skin and is responsible for the immediate tanning effect. Furthermore, it also contributes to skin ageing and wrinkling. For a long time it was thought that UVA could not cause any lasting damage. Recent studies strongly suggest that it may also enhance the development of skin cancers.

Treatment: One is prevention and avoid sun light when it is out the strongest in ultra-violet rays 12pm to 3pm and always use sunscreen.

Polymorphic light eruption (PLE) is the most common form of immunologically mediated photosensitivity dermatoses. Exposure to sunlight in spring or summer results in an irritable rash that resolves within a few days, providing further exposure is avoided.

The following treatments may reduce the severity of PLE:

  • Topical corticosteroid creams to relieve symptoms
  • Short course of oral steroids, eg to cover a summer holiday
  • Hydroxychloroquine
  • Phototherapy: UVB narrowband UVB, or PUVA for several weeks in early spring.

Are there any other health issues related to UV radiation?

In addition to cancer, exposure to UV rays can cause other health problems. UV rays, either from the sun or from artificial sources like tanning beds, can cause sunburn. In some people, exposure to UV rays can cause a rash or a type of allergic reaction. Exposure to UV rays can also cause premature aging of the skin and signs of sun damage such as liver spots, actinic keratosis=solar elastosis and both are precancerous skin condition.

UV rays can also cause eye problems. They can cause the cornea (on the front of the eye) to become inflamed or burned. They can also lead to the formation of cataracts (clouding of the lens of the eye) and pterygium (tissue growth on the surface of the eye), both of which can impair vision.

Exposure to UV rays can also weaken the immune system, so that the body has a harder time fending off infections. This can lead to problems such as reactivation of herpes triggered by exposure to the sun or other sources of UV rays. It can also cause vaccines to be less effective.

Some medications can make you more sensitive to UV radiation, making you more likely to get sunburned. Certain medical conditions can be made worse by UV radiation.

The benefits of Vit D and how it lowers the risk of some cancers!

Doctors are learning that vitamin D has many health benefits. It might even help lower the risk for some cancers. Your skin makes vitamin D naturally when it is exposed to UV rays from the sun. How much vitamin D you make depends on many things, including how old you are, how dark your skin is, and how strong the sunlight is where you live.

At this time, doctors aren’t sure what the optimal level of vitamin D is. A lot of research is being done in this area. Whenever possible, it’s better to get vitamin D from your diet or vitamin supplements rather than from exposure to UV rays because dietary sources and vitamin supplements do not increase skin cancer risk, and are typically more reliable ways to get the amount you need.

Remember tips about UV rays for men and women:

Men, especially those with lighter skin, are more likely than anybody else to get skin cancer, including melanoma—the deadliest kind of skin cancer.

When you think about sun protection, you might think about a day at the beach. But over your lifetime, you get sun exposure doing everyday things like biking, working, running, or even mowing the lawn. Sun exposure is the main source of ultraviolet (UV) rays, which can cause skin cancer. And UV exposure adds up over time, increasing your risk of developing skin cancer.

Men tend to get more sun exposure than women. Men spend more time outside over their lifetimes than women, and they’re more likely to work outdoors than women. Women’s personal care products, like moisturizer and makeup, often contain sunscreen, while many products for men don’t.

About one-third of U.S. adults get sunburned each year. Sunburn, which can increase your risk of getting skin cancer, is common among white men, young adults, and men who tan indoors. When outside on a sunny day for more than an hour, only about 14% of men use sunscreen on both their face and other exposed skin.

Seek shade, especially during midday hours. This includes 10 am to 4 pm, March through October, and 9 am to 3 pm, November through February. Umbrellas, trees, or other shelters can provide relief from the sun.

Wear a long-sleeved shirt and pants or a long skirt for additional protection when possible. If that’s not practical, try wearing a T-shirt or a beach cover-up.

Apply a thick layer of broad spectrum sunscreen with an SPF of 15 or higher at least 15 minutes before going outside, even on cloudy or overcast days. Reapply sunscreen at least every 2 hours and after swimming, sweating, or toweling off.

Indoor and outdoor tanning often begin in the teen years and continue into adulthood. Don’t wait to teach your children about the dangers of tanning. Children may be more receptive than teens, so start the conversation early, before they start outdoor tanning or indoor tanning. For example, you can Discourage tanning, even if it’s just before one event like prom. UV exposure adds up over time. Every time you tan, you increase your risk of getting skin cancer.  Help preteens and teens understand the dangers of tanning so they can make healthy choices.

There is no such thing as a safety tan!!!!

QUOTE FOR THURSDAY:

“Most skin cancers are caused by too much exposure to ultraviolet (UV) light. Protection from UV rays is important all year. Spending time outside is a great way to be physically active and reduce stress. You can work and play outside without raising your skin cancer risk by protecting your skin from the sun.

Most skin cancers are caused by too much exposure to ultraviolet (UV) light. UV rays are an invisible kind of radiation that comes from the sun, tanning beds, and sunlamps. UV rays can damage skin cells.

Protection from UV rays is important all year, not just during the summer. UV rays can reach you on cloudy and cool days, and they reflect off of surfaces like water, cement, sand, and snow. In the continental United States, UV rays tend to be strongest from 10 a.m. to 4 p.m. daylight saving time (9 a.m. to 3 p.m. standard time).

The UV Index forecasts the strength of UV rays each day. If the UV index is 3 or higher in your area, protect your skin from too much exposure to the sun.”

Centers for Disease Control and Prevention – CDC (https://www.cdc.gov/skin-cancer/sun-safety/index.html)

Part I July UV Safety Month – What’s Photosensitivity, Types of Ultra Rays, and PLE – Polymorphic Light Eruption and causes of PLE!

Polymorphic light eruption PLE 2       Polymorphic light eruption PLE

 

The Sun is by far the largest object in the solar system. It contains more than 99.8% of the total mass of the Solar System (Jupiter contains most of the rest).

It is often said that the Sun is an “ordinary” star. That’s true in the sense that there are many others similar to it. But there are many more smaller stars than larger ones; the Sun is in the top 10% by mass. The median size of stars in our galaxy is probably less than half the mass of the Sun. A process called fusion heats the Sun. Fusion happens in the core of the Sun. It is very hot there. In fact, the core’s average temperature is around 27,000,000 degrees Fahrenheit. The surface of the Sun is cool compared with the core, only 10,000 degrees Fahrenheit.

This fusion process not only heats the Sun, it makes the sunlight we see here on Earth. This sunlight travels the speed of light which is 186,282 miles per second or 299,792,458 meters per second. This means the light from the Sun takes 8.4 minutes to travel 93 million miles to Earth. If the world’s fastest land animal were to travel that same distance, it would take a cheetah over 151 years to reach the Earth running about 70 mph nonstop!

Ultraviolet radiation: Invisible rays that are part of the energy that comes from the sun. Ultraviolet radiation can burn the skin and cause skin cancer.

Ultraviolet radiation is made up of three types of rays — ultraviolet A, ultraviolet B, and ultraviolet C. Although ultraviolet C is the most dangerous type of ultraviolet light in terms of its potential to harm life on earth, it cannot penetrate earth’s protective ozone layer. Therefore, it poses no threat to human, animal or plant life on earth.

Ultraviolet A and ultraviolet B, on the other hand, do penetrate the ozone layer in attenuated form and reach the surface of the planet. Because ultraviolet A is weaker than ultraviolet B, scientists long blamed ultraviolet B as the sole culprit in causing skin cancer in persons with a history of sunburn and repeated overexposure to ultraviolet radiation. Recent research, however, has also implicated ultraviolet A as a possible cause of skin cancer.

Photosensitivity refers to various symptoms, diseases and conditions caused or aggravated by exposure to sunlight.

  • A rash due to photosensitivity is a photodermatosis (plural photodermatoses).
  • If the rash is eczematous, it is a photodermatitis.
  • A chemical or drug that causes photosensitivity is a photosensitiser.
  • A phototoxic reaction to a photosensitiser results in an exaggerated sunburn reaction and no immune reaction is involved.
  • A photoallergic reaction to a photosensitiser results in photodermatitis and is due to delayed hypersensitivity reaction.
  • A photoexacerbated condition describes a flare of an underlying skin disease on exposure to sunlight.

Photosensitivity is characterized into many groups:

  • Polymorphic light eruption (PLE):

PLE generally affects adult females aged 20–40, although it sometimes affects children and males (25%). It is particularly common in places where sun exposure is uncommon, such as Northern Europe, where it is said to affect 10–20% of women holidaying in the Mediterranean area. It is less common in Australasia. It has also been reported to be relatively common at higher altitudes compared to sea level.

PLE can occur in all races and skin phototypes and may be more prevalent in skin of colour than in white skin. There is a genetic tendency to PLE, and it is sometimes associated with or confused with photosensitivity due to lupus erythematosus (which generally is more persistent than PLE).

Some patients experience PLE during phototherapy, which is used to treat skin conditions such as psoriasis and dermatitis.

There are three types of UV rays:

Ultraviolet A (UVA): UVA rays penetrate deep into the layers of the skin and lead to premature signs of aging, which include fine lines and wrinkles. It is important to note that the amount of UVA stays relatively consistent throughout the year, and exceeds the amount of UVB in both summer and winter. Even on a cloudy day, 80% of the sun’s UVA rays pass through the clouds and reach our skin and eyes. It’s also important to know that tanning beds work by emitting primarily UVA rays.

Ultraviolet B (UVB): UVB rays are the primary cause of sunburn, thickening of the skin, and several types of skin cancers – including melanoma. UVB rays penetrate the outermost layer of skin and cause damage to skin cells. UVB also can cause damage to eyes and the immune system.

Ultraviolet C (UVC): UVC is the strongest of the UV spectrum radiation. Fortunately, UVC rays do not reach the earth’s surface because it is blocked by the ozone layer of the atmosphere. The only way we can be exposed to UVC radiation is from an artifical source, such as a lamp or laser. UVC rays can cause severe skin burns and eye injuries even when exposed for only a few seconds. Since the penetration depth of UVC rays is very low, these injuries usually resolve within a week with virtually no risk of long-term health risks (skin cancer, cateracts, vision loss).

Causes:

Genetic factors may be important with many affected individuals reporting a family history of PLE. Native Americans have a hereditary form of PLE (actinic prurigo).

PLE is caused by a delayed hypersensitivity reaction to a compound in the skin that is altered by exposure to ultraviolet radiation (UVR). UVR leads to impaired T cell function and altered production of cytokines in affected individuals. There is a reduction in the normal UV-induced immune suppression in the skin. This has been suggested to be either due to oestrogen or deficiency of vitamin D.

The rash is usually provoked by UVA (in 90%). This means the rash can occur when the sunlight is coming through window glass, and that standard sunscreens may not prevent it. Occasionally, UVB and/or visible light provoke PLE.

PLE may be a rare occurrence in the individual concerned or may occur every time the skin is exposed to sunlight. In most affected individuals, it occurs each spring, provoked by several hours outside on a sunny day. If further sun exposure is avoided, the rash settles in a few days and is gone without a trace within a couple of weeks. It can recur next time the sun shines on the skin. However, if the affected area is exposed to more sun before it has cleared up, the condition tends to get more severe and extensive with longer to heal.

Stay tune tomorrow for part II on Ultralight rays from the Sun to Sunburn and Types of photosensitivity for some!

QUOTE FOR WEDNESDAY:

“According to the World Health Organization (WHO),  each year nearly 20 million pregnant women carry group B strep (GBS). Although GBS is harmless for most pregnant individuals, it can be extremely serious when it passes to babies during pregnancy, childbirth or in the first months of life.”

www.groupBstrepinternational (Group B Strep International – Home)

 

International Group B Strep Awareness

 

Group B Streptococcus (GBS), or Streptococcus agalactiae, is a type of bacteria that is naturally found in the digestive and lower reproductive tracts of both men and women.  About 1 in 4 pregnant women “carry” or are “colonized” with GBS.

Carrying GBS does not mean that you are unclean.  Anyone can carry GBS. GBS is not considered to be a sexually transmitted disease or infection as it can occur on its own even in someone with no prior sexual experience. However, bacteria can be passed between sexual partners, including through oral contact.

The awareness month for group B strep is July. This is a common bacterium that affects adults and it does not present with any symptoms or signs. The pregnant women can pass these bacteria to their unborn children during the first few months after delivery or during child birth and this can be fatal. Most people who suffer from this bacterial infection are not aware of it and pregnant women get to know about it because of the screening that is done during prenatal visits. The screening tests is usually done during the third trimester and this test was started in the mid 1990s. Research indicates that since that time, the number of children who are affected by this infection has dropped from 1.7 to 0.28 in every 1000 births.

This month helps in raising awareness to women who are pregnant and those who are in the child rearing period to prevent Group B Strep infection. This helps women to keep their unborn babies healthy and safe as the infection can be fatal.

The National Charity that is associated with group B strep advices all pregnant women to be aware of this infection caused by streptococcus group B. This is the most common type of infection in new born babies as it causes meningitis, pneumonia and sepsis which can be fatal in the first few weeks of life. The bacterium is carried by women who do not present with any symptoms and therefore it can be easily passed to the baby during child birth.

The main message that is shared on this month awareness is that Group B Strep is fatal and that the infection can be prevented. People are taught on the need to go for testing as the bacterial colonization can be carried by people in the vagina or the lower intestines. Most people are carriers of this infection but they are not aware because they have never been tested for the same. This is because the infection does not present with any signs or symptoms. However, in some cases, the infection can get access into the blood stream and this can trigger fatal infections. When a pregnant woman gets this infection it can be spread to the unborn baby in the following ways:

While the baby is still in the womb, during a normal or a cesarean section birth, through the urinary tract or amniotic fluid, or through direct contact with the bacteria that is present in the birth canal.

The infants who are infected by this bacterium during birth are prone to infections and this includes meningitis, pneumonia and sepsis. The children who survive this infection are at risk of getting long term complications especially in cases where they suffered from meningitis. The common complications that can occur include cerebral palsy, hearing loss, mental and physical disabilities.

Pregnant women should be aware of the need for testing for each pregnancy and it does not matter whether they were tested for the previous pregnancies. This is because all pregnancies are different and it is vital to ensure that the baby is safe in all pregnancies.

 

QUOTE FOR TUESDAY:

“July is National Cleft and Craniofacial Awareness and Prevention Month, a time to raise awareness and improve understanding of orofacial clefts (clefts of the lip and palate) and other conditions of the head and face (Centers for Disease Control and Prevention, 2015). About 1 in every 1,600 babies is born with cleft lip with cleft palate in the United States (Centers for Disease Control and Prevention, 2023). What are the potential effects of orofacial clefts and other craniofacial conditions on the child? Children with orofacial clefts and other craniofacial conditions often have impaired ability to feed and impaired language development, and might be at increased risk for a greater number of ear infections, hearing issues, and problems with their teeth.

Recently childlife.org found the following information about this diagnosis.  In 2023 important findings from research studies about some factors that increase the chance of having a baby with an orofacial cleft:

  • Smoking―Women who smoke during pregnancy are more likely to have a baby with an orofacial cleft than women who do not smoke.
  • Diabetes―Women with diabetes diagnosed before pregnancy have an increased risk of having a child with a cleft lip with or without cleft palate, compared to women who did not have diabetes.
  • Use of certain medicines―Women who used certain medicines to treat epilepsy, such as topiramate or valproic acid, during the first trimester (the first 3 months) of pregnancy have an increased risk of having a baby with cleft lip with or without cleft palate, compared to women who didn’t take these medicines.”

Association of Child Life Professionals (National Cleft and Craniofacial Awareness and Prevention Month ​)

Part II National Craniofacial and Cleft Palate Awareness and Prevention Month!

birth defect6

Health care providers are encouraged to provide women to plan for pregnancy; avoid harmful substances, like tobacco (2) and alcohol (3); and choose a healthy lifestyle, like eating a healthy diet (4), to increase their chances of a healthy pregnancy. Health care providers also discuss with women any medications they might be taking, both prescription and over-the-counter, to ensure they are taking only what is necessary. If yours is not maybe you need a new one. Prevention is the key to giving highier odds the baby will be healthier when born. Re-enforcement is a great tool and that’s where the medical profession comes into play with pregnant women who is their clientele.

Know that not all birth defects can be prevented. But, we also know that women can increase their chances of having a healthy baby by managing health conditions and adopting healthy behaviors before becoming pregnant. Make a commitment to yourself, to get healthy before and during pregnancy by actively trying to plan ahead, avoid harmful substances, choose a healthy lifestyle, and talk with your healthcare provider.   There are some that can be prevented.

1.Plan ahead.

Get 400 micrograms (mcg) of folic acid every day. Folic acid is a B vitamin. If a woman has enough folic acid in her body at least one month before and during pregnancy, it can help prevent major birth defects of the developing brain and spine defects like anencephaly or spina bifida. Anencephaly is a serious birth defect in which a baby is born without parts of the brain and skull. It is a type of neural tube defect (NTD). As the neural tube forms and closes, it helps form the baby’s brain and skull (upper part of the neural tube), spinal cord, and back bones (lower part of the neural tube). Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD). Spina bifida can happen anywhere along the spine if the neural tube does not close all the way. The backbone that protects the spinal cord does not form and close as it should. This often results in damage to the spinal cord and nerves. Spina bifida might cause physical and intellectual disabilities that range from mild to severe. The severity depends on:

  • The size and location of the opening in the spine.
  • Whether part of the spinal cord and nerves are affected.
  • There are 3 types and they are: 1-Myelomeningocele, 2-Meningocele, and 3-Spina Bifida Occulta.
  • 1-Myelomeningocele is the most serious type of spina bifida. With this condition, a sac of fluid comes through an opening in the baby’s back. Part of the spinal cord and nerves are in this sac and are damaged. This type of spina bifida causes moderate to severe disabilities, such as problems affecting how the person goes to the bathroom, loss of feeling in the person’s legs or feet, and not being able to move the legs.
  • 2-Meninocele is a sac of fluid comes through an opening in the baby’s back. But, the spinal cord is not in this sac. There is usually little or no nerve damage. This type of spina bifida can cause minor disabilities.
  • 3-Spina bifida occulta is the mildest type of spina bifida. It is sometimes called “hidden” spina bifida. With it, there is a small gap in the spine, but no opening or sac on the back. The spinal cord and the nerves usually are normal. Many times, spina bifida occulta is not discovered until late childhood or adulthood. This type of spina bifida usually does not cause any disabilities.
    • Women can get folic acid from fortified foods or supplements, or a combination of the two, in addition to a varied diet rich in folate.
    • See a healthcare professional regularly. A woman should be sure to see her doctor when planning a pregnancy and start prenatal care as soon as she thinks that she is pregnant. It is important to see the doctor regularly throughout pregnancy, so a woman should keep all her prenatal care appointments. If you are trying to have a baby or are just thinking about it, it is not too early to start getting ready for pregnancy. Use these checklists to help you write down your goals and have them in a place that you reinforce yourself to maintain them as best as possible for your child’s sake and your own sake as well.

2.Avoid harmful substances.

    • Avoid alcohol at any time during pregnancy.                                    
    • Alcohol in a woman’s bloodstream passes to the developing baby through the umbilical cord. There is no known safe amount of alcohol use during pregnancy or while trying to get pregnant. There is also no safe time during pregnancy to drink. All types of alcohol are equally harmful, including wine and beer. Drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong physical, behavioral, and These disabilities in the child, which occur because the mother drank alcohol during the pregnancy, are known as fetal alcohol spectrum disorders (FASDs). The best advice for women is to stop drinking alcohol when trying to get pregnant.
    • Avoid smoking cigarettes.
    • The dangers of smoking during pregnancy include preterm birth, certain birth defects from cleft lip or cleft palate to even infant death and more diseases inherited by mom through smoking. Even being around tobacco smoke puts a woman and her pregnancy at risk for problems. Quitting smoking before getting pregnant is best. For a woman who is already pregnant, quitting as early as possible can still help protect against some health problems for the baby, such as low birth weight. It’s never too late to quit smoking.
    • Avoid marijuana and other “street drugs”.
    • A woman who uses marijuana or other “street” drugs during pregnancy can have a baby who is born preterm, of low birth weight, or has other health problems, such as birth defects. Marijuana is the illicit drug most commonly used during pregnancy. Since we know of no safe level of marijuana use during pregnancy, women who are pregnant, or considering becoming pregnant, should not use marijuana, even in states where marijuana is legal. Women using marijuana for medical reasons should speak with their doctor about an alternative therapy with pregnancy-specific safety data.
    • Prevent infections.
    • Some infections that a woman can get during pregnancy can be harmful to the developing baby and can even cause birth defects. Some easy steps to prevent infections include frequent hand-washing, cooking meat until its well done, and staying away from people who have an infection. 

3.Choose a healthy lifestyle.

    • Keep diabetes under control.
    • Poor control of diabetes during pregnancy increases the chances for birth defects and other problems for the pregnancy. It can also cause serious complications for the woman. Proper healthcare before and during pregnancy can help prevent birth defects and other poor outcomes.
    • Strive to reach and maintain a healthy weight.
    • Do you know …Your body mass index (BMI)? Calculate it. Where? Just look it up on the internet anywhere for free.

A woman who is obese (a Body Mass Index of 30 or higher) before pregnancy is at a higher risk for complications during pregnancy. Obesity also increases a pregnant woman’s risk of several serious birth defects. Even if a woman is not actively planning a pregnancy, getting healthy can help boost her health and her mood. If a woman is overweight or obese, she should talk with her doctor about ways to reach a healthy weight before she gets pregnant.

4.Talk with your healthcare provider.

    • Talk to a healthcare provider about taking any medications.
    • We know that certain medications can cause serious birth defects if they are taken during pregnancy. For many medications taken by pregnant women, the safety has been difficult to determine. Despite the limited safety data, some medications are needed to treat serious conditions. If a woman is pregnant or planning a pregnancy, she should not stop taking medications she needs or begin taking new medications without first talking with her healthcare provider. This includes prescription and over-the-counter medications and dietary or herbal products.
    • Talk to a healthcare provider about vaccinations (shots).                                                

Most vaccinations are safe during pregnancy and some vaccinations, such as the flu vaccine and the Tdap vaccine (adult tetanus, diphtheria and acellular pertussis vaccine), are specifically recommended during pregnancy. Some vaccines protect women against infections that can cause birth defects. Having the right vaccinations at the right time can help keep a woman and her baby healthy. She should talk to her doctor about which vaccines are recommended for her during pregnancy.

ACPC-American Cleft Palate – Craniofacial Association addresses July the month of awareness to this condition with stating:

“Here are five key facts about clefts and craniofacial conditions, their impact and treatments:

  1. Clefts are usually repaired surgically in the first year of life, though many children require additional surgeries and treatments through adolescence to correct challenges to breathing, eating or speech development.
  2. Individuals born with cleft lip or palate often need specialized dental or orthodontic care throughout their lives as well.
  3. There is no single factor related to the cause of cleft. Sometimes clefts run in families and in some cases have been linked to environmental factors.
  4. Despite unique health challenges, those born with cleft and craniofacial conditions lead fulfilling, successful and accomplished lives.
  5. Coordinated care is the best approach for successful surgical repair. Multidisciplinary teams approved by the ACPA are located across the nation and are comprised of qualified professionals from medical, surgical, dental, speech and allied health disciplines.”

Part I National Craniofacial and Cleft Palate Awareness and Prevention Month!

What is cleft lip and palate?

National Cleft and Craniofacial Awareness and Prevention Month is observed in July. This is an opportunity to raise awareness and improve understanding of orofacial clefts, clefts of the lip and palate, and other conditions of the head and face. In the United States, approximately 2,600 babies are born with a cleft palate and 4,400 babies are born with a cleft lip, with or without a cleft palate each year. There are other craniofacial birth defects including craniosynostosis (skull sutures fusing prematurely), anotia/microtia (ear is missing or underdeveloped), and anophthalmia/microphthalmia (missing or abnormally small eye).

There are several forms of cleft lip and palate, and each one requires a slightly different treatment. The three types of cleft lip and palate are

  • Unilateral incomplete
  • Unilateral complete
  • Bilateral complete

What causes cleft lip and cleft palate?

We’re not sure what causes cleft lip and cleft palate. They may be caused by a combination of factors, like genes and things in your everyday life, like certain medicines you take. Risk factors include:

  • Having a family history of cleft lip and cleft palate
  • Smoking or drinking alcohol during pregnancy
  • Having diabetes before pregnancy
  • Taking certain anti-seizure medicines during the first trimester of pregnancy, like topiramate or valproic acid
  • Being obese during pregnancy.
  • Having certain infections during pregnancy, like rubella (also called German measles)

How are Cleft lip and palate treated?

Cleft lip and palate can cause problems with speech, eating, hearing, and social development. Most of the time, cleft lip and palate can be easily treated with corrective surgery, allowing children born with the condition to live normal lives. However, in some cases – particularly in developing countries where access to medical care is not as widely available – children do not receive treatment. This can result in further problems as the child grows.

July is National Cleft and Craniofacial Awareness and Prevention Month.

Cleft lip and cleft palate happen when a baby’s lip or mouth doesn’t form completely during pregnancy. Cleft lip is an opening in a baby’s upper lip. Cleft palate is an opening in the roof of a baby’s mouth. Cleft lip and cleft palate are birth defects. These conditions affect thousands of babies, children, teens and adults in the United States each year.

Cleft lip and palate happen very early in pregnancy. Your baby’s lips form between 4 and 7 weeks of pregnancy, and the palate forms between 6 and 9 weeks of pregnancy. Cleft lip and palate don’t have to happen together — a baby can have one without the other.

Prevention:

To help reduce the chances of having a baby with an orofacial cleft or other craniofacial condition health care providers must encourage patients who are thinking about becoming pregnant to commit to a healthy lifestyle. Among certain healthy habits, we have: control diabetes, quit smoking, exercise regularly, practice yoga, etc. before becoming pregnant. Moreover, health care providers should also work with prospective parents to make informed decisions about medical treatment during pregnancy. This condition can occur in the first three months of pregnancy. Therefore, steps before becoming pregnant are essential for the health of the baby.

 

QUOTE FOR THE WEEKEND:

“Cord blood is the blood remaining in your baby’s umbilical cord after he or she is born. This blood is rich with nutrients and stem cells, a type of cell that can regenerate and replace damaged cells with newer, healthier ones. Cord blood banking — also known as stem cell banking — refers to how we cryogenically preserve these cells for future medical or therapeutic use.

Storing your child’s stem cells will offer them the most comprehensive, cutting-edge treatment opportunities in the future. Regenerative medicine is a rapidly expanding field that creates extensive opportunities for your child to use their stored stem cells. Having access to stored stem cells can alleviate the trouble of locating a stem cell donor, securing a match, or facing incompatibility risks. Plus, your newborn’s stem cells have the potential to provide life-saving treatment for other matching family members, including siblings, parents, and grandparents.

As a result, storing your child’s stem cells could offer them immediate access to over 80 FDA-approved treatment opportunities and hundreds of clinical trials, including:  malignant diseases, non-malignant conditions including congenital conditions, and metabolic disorders.”

Like all blood it is so precious!

Americord Registry (Best Offer Landing | Americord Registry)

 

Cord Blood Awareness Month

July is National Cord Blood Awareness Month, and it’s the perfect time to learn more about cord blood—a biological product regulated by the Food and Drug Administration. Found in the blood vessels of the placenta and the umbilical cord, cord blood is collected after a baby is born and after the umbilical cord is cut—an important point.

“Because cord blood is typically collected after the baby is delivered and the cord is cut, the procedure is generally safe for the mother and baby,” explains Keith Wonnacott, Ph.D., Chief of the Cellular Therapies Branch in FDA’s Office of Cellular, Tissue, and Gene Therapies.

Approved Uses By the Food and Drug Administration states the following:

Cord blood is approved only for use in “hematopoietic stem cell transplantation” procedures, which are done in patients with disorders affecting the hematopoietic (blood forming) system. Cord blood contains blood-forming stem cells that can be used in the treatment of patients with blood cancers such as leukemias and lymphomas, as well as certain disorders of the blood and immune systems, such as sickle cell disease and Wiskott-Aldrich syndrome.

“Cord blood is useful because it is a source of stem cells that form into blood cells. Cord blood can be used for transplantation in people who need regeneration, that is, ‘regrowth,’ of these blood-forming cells,” Wonnacott says.

For instance, in many cancer patients, the disease is found in the blood cells. Chemotherapy treatment of these patients kills both cancer cells and the healthy blood-forming stem cells. Transplanted stem cells from cord blood can help regrow the healthy blood cells after the chemotherapy.

However, cord blood is not a cure-all.

“Because cord blood contains stem cells, there have been stem cell fraud cases related to cord blood,” says Wonnacott. “Consumers may think that stem cells can cure any disease, but science doesn’t show this to be the case. Patients should be skeptical if cord blood is being promoted for uses other than blood stem cell regeneration.”

About Cord Blood Banking

After cord blood is collected, it is frozen and can be safely stored for many years. “The method of freezing, called ‘cryopreservation,’ is very important to maintain the integrity of the cells,” Wonnacott says. “Cord blood needs to be stored carefully.”

You may choose to store your baby’s cord blood in a private bank so it can be available if needed in the future by your child or first- or second-degree relatives. Private cord banks typically charge fees for blood collection and storage.

Or you may donate the cord blood to a public bank so that doctors can use for a patient who needs a hematopoietic stem cell transplant.

FDA regulates cord blood in different ways, depending on the source, level of processing and intended use.

Cord blood stored for personal use, for use in first- or second-degree relatives, and that also meets other criteria in FDA’s regulations, does not require the agency’s approval before use. Private cord banks must still comply with other FDA requirements, including establishment registration and listing, current good tissue practice regulations, and donor screening and testing for infectious diseases (except when cord blood is used for the original donor). These FDA requirements ensure safety of these products by minimizing the risk of contamination and transmission of infectious diseases.

Cord blood stored for use by a patient unrelated to the donor meets the legal definitions of both a “drug” and a “biological product.” Cord blood in this category must meet additional requirements and be licensed under a biologics license application, or be the subject of an investigational new drug application before use. The FDA requirements help to ensure that these products are safe and effective for their intended use.

Not every cord blood unit will meet requirements for public banking, adds Safa Karandish, M.T., an FDA consumer safety officer. If that happens, some of this donated cord blood may be used for non-clinical research.