“Cord blood is the blood remaining in your baby’s umbilical cord after he or she is born. This blood is rich with nutrients and stem cells, a type of cell that can regenerate and replace damaged cells with newer, healthier ones. Cord blood banking — also known as stem cell banking — refers to how we cryogenically preserve these cells for future medical or therapeutic use.

Storing your child’s stem cells will offer them the most comprehensive, cutting-edge treatment opportunities in the future. Regenerative medicine is a rapidly expanding field that creates extensive opportunities for your child to use their stored stem cells. Having access to stored stem cells can alleviate the trouble of locating a stem cell donor, securing a match, or facing incompatibility risks. Plus, your newborn’s stem cells have the potential to provide life-saving treatment for other matching family members, including siblings, parents, and grandparents.

As a result, storing your child’s stem cells could offer them immediate access to over 80 FDA-approved treatment opportunities and hundreds of clinical trials, including:  malignant diseases, non-malignant conditions including congenital conditions, and metabolic disorders.”

Like all blood it is so precious!

Americord Registry (Best Offer Landing | Americord Registry)

July is National Cord Blood Awareness Month, and it’s the perfect time to learn more about cord blood—a biological product regulated by the Food and Drug Administration. Found in the blood vessels of the placenta and the umbilical cord, cord blood is collected after a baby is born and after the umbilical cord is cut—an important point.

“Because cord blood is typically collected after the baby is delivered and the cord is cut, the procedure is generally safe for the mother and baby,” explains Keith Wonnacott, Ph.D., Chief of the Cellular Therapies Branch in FDA’s Office of Cellular, Tissue, and Gene Therapies.

Approved Uses By the Food and Drug Administration states the following:

Cord blood is approved only for use in “hematopoietic stem cell transplantation” procedures, which are done in patients with disorders affecting the hematopoietic (blood forming) system. Cord blood contains blood-forming stem cells that can be used in the treatment of patients with blood cancers such as leukemias and lymphomas, as well as certain disorders of the blood and immune systems, such as sickle cell disease and Wiskott-Aldrich syndrome.

“Cord blood is useful because it is a source of stem cells that form into blood cells. Cord blood can be used for transplantation in people who need regeneration, that is, ‘regrowth,’ of these blood-forming cells,” Wonnacott says.

For instance, in many cancer patients, the disease is found in the blood cells. Chemotherapy treatment of these patients kills both cancer cells and the healthy blood-forming stem cells. Transplanted stem cells from cord blood can help regrow the healthy blood cells after the chemotherapy.

However, cord blood is not a cure-all.

“Because cord blood contains stem cells, there have been stem cell fraud cases related to cord blood,” says Wonnacott. “Consumers may think that stem cells can cure any disease, but science doesn’t show this to be the case. Patients should be skeptical if cord blood is being promoted for uses other than blood stem cell regeneration.”

About Cord Blood Banking

After cord blood is collected, it is frozen and can be safely stored for many years. “The method of freezing, called ‘cryopreservation,’ is very important to maintain the integrity of the cells,” Wonnacott says. “Cord blood needs to be stored carefully.”

You may choose to store your baby’s cord blood in a private bank so it can be available if needed in the future by your child or first- or second-degree relatives. Private cord banks typically charge fees for blood collection and storage.

Or you may donate the cord blood to a public bank so that doctors can use for a patient who needs a hematopoietic stem cell transplant.

FDA regulates cord blood in different ways, depending on the source, level of processing and intended use.

Cord blood stored for personal use, for use in first- or second-degree relatives, and that also meets other criteria in FDA’s regulations, does not require the agency’s approval before use. Private cord banks must still comply with other FDA requirements, including establishment registration and listing, current good tissue practice regulations, and donor screening and testing for infectious diseases (except when cord blood is used for the original donor). These FDA requirements ensure safety of these products by minimizing the risk of contamination and transmission of infectious diseases.

Cord blood stored for use by a patient unrelated to the donor meets the legal definitions of both a “drug” and a “biological product.” Cord blood in this category must meet additional requirements and be licensed under a biologics license application, or be the subject of an investigational new drug application before use. The FDA requirements help to ensure that these products are safe and effective for their intended use.

Not every cord blood unit will meet requirements for public banking, adds Safa Karandish, M.T., an FDA consumer safety officer. If that happens, some of this donated cord blood may be used for non-clinical research.

“Juvenile idiopathic arthritis, formerly known as juvenile rheumatoid arthritis, is the most common type of arthritis in children under the age of 16.

Juvenile idiopathic arthritis occurs when the body’s immune system attacks its own cells and tissues. It’s not known why this happens, but both heredity and environment seem to play a role. Some forms of juvenile idiopathic arthritis are more common in girls.”

MAYO CLINIC (https://www.mayoclinic.org/diseases-conditions/juvenile-idiopathic-arthritis/symptoms-causes/syc-20374082)”

How Juvenile Arthritis (JIA) is Diagnosis:

Diagnosis of juvenile idiopathic arthritis can be difficult because joint pain can be caused by many different types of problems. No single test can confirm a diagnosis, but tests can help rule out some other conditions that produce similar signs and symptoms.

1. Blood tests

Some of the most common blood tests for suspected cases include:

• Erythrocyte sedimentation rate (ESR). The sedimentation rate is the speed at which your red blood cells settle to the bottom of a tube of blood. An elevated rate can indicate inflammation. Measuring the ESR is primarily used to determine the degree of inflammation.
• C-reactive protein. This blood test also measures levels of general inflammation in the body but on a different scale than the ESR.
• Antinuclear antibody. Antinuclear antibodies are proteins commonly produced by the immune systems of people with certain autoimmune diseases, including arthritis. They are a marker for an increased chance of eye inflammation.
• Rheumatoid factor. This antibody is occasionally found in the blood of children who have juvenile idiopathic arthritis and may mean there’s a higher risk of damage from arthritis.
• Cyclic citrullinated peptide (CCP). Like the rheumatoid factor, the CCP is another antibody that may be found in the blood of children with juvenile idiopathic arthritis and may indicate a higher risk of damage.

In many children with juvenile idiopathic arthritis, no significant abnormality will be found in these blood tests.

2. Imaging scans

X-rays or magnetic resonance imaging may be taken to exclude other conditions, such as fractures, tumors, infection or congenital defects.

Imaging may also be used from time to time after the diagnosis to monitor bone development and to detect joint damage.

Juvenile Arthritis (JIA) Treatment:

Treatment for juvenile idiopathic arthritis focuses on helping your child maintain a normal level of physical and social activity. To accomplish this, doctors may use a combination of strategies to relieve pain and swelling, maintain full movement and strength, and prevent complications.

1. Medications

The medications used to help children with juvenile idiopathic arthritis are chosen to decrease pain, improve function and minimize potential joint damage.

Typical medications include:

• Nonsteroidal anti-inflammatory drugs (NSAIDs). These medications, such as ibuprofen (Advil, Motrin, others) and naproxen sodium (Aleve), reduce pain and swelling. Side effects include stomach upset and, much less often, kidney and liver problems.
• Disease-modifying antirheumatic drugs (DMARDs). Doctors use these medications when NSAIDs alone fail to relieve symptoms of joint pain and swelling or if there is a high risk of damage in the future.DMARDs may be taken in combination with NSAIDs and are used to slow the progress of juvenile idiopathic arthritis. The most commonly used DMARD for children is methotrexate (Trexall, Xatmep, others). Side effects of methotrexate may include nausea, low blood counts, liver problems and a mild increased risk of infection.
• Biologic agents. Also known as biologic response modifiers, this newer class of drugs includes tumor necrosis factor (TNF) blockers, such as etanercept (Enbrel, Erelzi, Eticovo), adalimumab (Humira), golimumab (Simponi) and infliximab (Remicade, Inflectra, others). These medications can help reduce systemic inflammation and prevent joint damage. They may be used with DMARDs and other medications.Other biologic agents work to suppress the immune system in slightly different ways, including abatacept (Orencia), rituximab (Rituxan, Truxima, Ruxience), anakinra (Kineret) and tocilizumab (Actemra). All biologics can increase the risk of infection.
• Corticosteroids. Medications such as prednisone may be used to control symptoms until another medication takes effect. They are also used to treat inflammation when it is not in the joints, such as inflammation of the sac around the heart.These drugs can interfere with normal growth and increase susceptibility to infection, so they generally should be used for the shortest possible duration.

2. Therapies

Your doctor may recommend that your child work with a physical therapist to help keep joints flexible and maintain range of motion and muscle tone.

A physical therapist or an occupational therapist may make additional recommendations regarding the best exercise and protective equipment for your child.

A physical or occupational therapist may also recommend that your child make use of joint supports or splints to help protect joints and keep them in a good functional position.

3. Surgery

In very severe cases, surgery may be needed to improve joint function.

***Parents or caregivers help limit the arthritis in your children by doing the following:

• Getting regular exercise. Exercise is important because it promotes both muscle strength and joint flexibility. Swimming is an excellent choice because it places minimal stress on joints.
• Applying cold or heat. Stiffness affects many children with juvenile idiopathic arthritis, particularly in the morning. Some children respond well to cold packs, particularly after activity. However, most children prefer warmth, such as a hot pack or a hot bath or shower, especially in the morning
•  Eating Well. Some children with arthritis have poor appetites. Others may gain excess weight due to medications or physical inactivity. A healthy diet can help maintain an appropriate body weight.Know adequate calcium in the diet is important because children with juvenile idiopathic arthritis are at risk of developing weak bones due to the disease, the use of corticosteroids, and decreased physical activity and weight bearing.

“Arthritis affects persons of all ages; little is known about arthritis prevalence among children and adolescents aged <18 years.

Approximately 220,000 children and adolescents had arthritis during 2017–2021. Prevalence increased with age and was highest among those aged 12–17 years, non-Hispanic Black or African American children and adolescents, children and adolescents with anxiety or depression, those who were physically inactive, had overweight or a heart condition, or lived in a food-insecure or smoking household.

Arthritis affects persons of all ages, including younger adults, adolescents, and children; however, recent arthritis prevalence estimates among children and adolescents aged <18 years are not available. Previous prevalence estimates among U.S. children and adolescents aged <18 years ranged from 21 to 403 per 100,000 population depending upon the case definition used. CDC analyzed aggregated 2017–2021 National Survey of Children’s Health data to estimate the national prevalence of parent-reported arthritis diagnosed among children and adolescents aged <18 years. An estimated 220,000 (95% CI = 187,000–260,000) U.S. children and adolescents aged <18 years (305 per 100,000) had diagnosed arthritis. Arthritis prevalence among non-Hispanic Black or African American children and adolescents was twice that of non-Hispanic White children and adolescents.”

Center for Disease Control and Prevention – CDC (Arthritis Among Children and Adolescents Aged 18 Years — United States, 2017–2021 | MMWR)

While 4th of July is a time for barbecues and parties, it can also increase the risk for accidents and injuries.  A recent survey found that unsafe fireworks displays and drunk driving are two of the biggest concerns for the upcoming holiday. Planning ahead – and prioritizing safety – are the keys to a safe and fun holiday.  Fourth of July is right around the corner, and there’s no better time to start preparing for barbecues, trips, and celebrations.

The survey findings highlighted some of the biggest safety risks that pop up around this time of year:

• Nearly 60% of respondents said they’ve seen unsafe fireworks use during 4th of July

• About 33% of Gen Z and Millennial respondents said they’ve been pressured into risky behavior

• Nearly 70% of respondents said they’ve seen someone try to drive drunk on 4th of July

• Under 30% of respondents said they trust other Americans to celebrate responsibly

“Stick with people and activities you are familiar with,” Steadman said. “Don’t take unnecessary risks or get caught up in a crowd of unruly people. Be cognizant of children and others who may need extra looking after.

“The 4th of July is a time for celebration of America and freedom. By taking the necessary precautions and avoiding risky behavior, everyone can enjoy the day. Stay vigilant and be prepared for if things go south, and always make sure you are practicing safe behavior with both fireworks and alcohol.”

Always keep a first aid kit nearby!”

Consumer Affairs (How to stay safe for 4th of July)

The Fourth of July is a time to celebrate with friends and family the vast opportunities our country has given us. While we reach the end of the COVID-19 pandemic, many Independence Day traditions and celebrations are a go, but that may not be the case everywhere. Be sure to check your local restrictions before hosting barbeques. If your state is fully opened and you plan to attend an event, be vigilant about your safety and that of your belongings. Here are a few other tips to help you get through the festivities.

WAYS TO STAY SAFE ON THE FOURTH OF JULY

1. Stay cool and hydrated especially in areas very hot!

July is one of the hottest times of the year and it’s easy to fall victim to sun or heat stroke. Stay cool by being a shade-seeker: bringing an umbrella with you, wearing a hat, or staying under the covered portion of a porch or patio. It’s equally as important to wear sunscreen as well as light and loose clothing.

Finally, don’t forget the water. Many times, we get caught up in festive food and drink options and forget to add in water. Aim for eight cups or more per day, depending on how hot it is outside or how much sweet or salty food you are consuming.

2. Consider the safety of your food

The heat not only has an impact on you but your food as well.  Having a BBQ and thinking of throwing all the meat on one platter outside awaiting the grill? Think again. Keep raw meat and seafood cold until it’s ready to be cooked. Once it’s ready, keep it hot until it’s consumed, then put in the fridge once everyone is done, meaning, don’t let it sit out. Contaminated food or items that have sat out too long can lead to food poisoning of some sickness, like infection.

3. Be mindful at events

Summer and celebrations mean concerts, BBQs, and state or county fairs. But it’s important to always be aware of your surroundings. Don’t leave your food, bag, or belongings unattended, and if the event is happening at night, be sure to stick with a friend. Fireworks are prime for theft as they are loud with those watching focused on the show.

4. Prevent eye injury

Prevent Blindness Texas has declared June 28th through July 4th as Fireworks Safety Awareness Week. Fireworks can damage your eyes, too. Contusions and lacerations are the most frequent injuries to eyes, which include foreign bodies in the eye.

If you do encounter an eye emergency, follow these steps to save your sight.

In the event of an eye emergency:

1. Do not rub the eye. Rubbing the eye may increase bleeding or make the injury worse.
2. Do not attempt to rinse out the eye. This can be even more damaging than rubbing.
3. Do not apply pressure to the eye itself. Holding or taping a foam cup or the bottom of a juice carton to the eye are just two tips. Protecting the eye from further contact with any item, including your hand, is the goal.
4. Do not stop for medicine! Over-the-counter pain relievers will not do much to relieve pain. Aspirin (should never be given to children) and Ibuprofen can thin the blood and increase bleeding. Go to the emergency room at once – this is more important than stopping for a pain reliever.
5. Do not apply ointment. Ointment, which may not be sterile, makes the area around the eye slippery and harder for the doctor to examine.

Overall, the best way to prevent eye or other injuries is to not play with fireworks and do not let your child play with fireworks, even if their friends are.

“If your holiday plans include fun in the water, make sure every member of your family is water smart ─ has swimming skills and knows how to help others in an emergency.

The American Red Cross offers these tips to help keep you and your loved ones safe during the upcoming 4th of July holidaay:

FIREWORKS SAFETY The safest way to enjoy fireworks is to attend a public fireworks show put on by professionals. Many states outlaw most fireworks, so consider celebrating with glow sticks, noise makers or silly string instead. If you choose to set fireworks off at home, follow these safety steps:

• Never give fireworks to small children, and never throw or point a firework toward people, animals, vehicles, structures or flammable materials.
• Always follow the instructions on the packaging.
• Keep a supply of water close by.
• Make sure the person lighting fireworks always wears eye protection.
• Light only one firework at a time and never attempt to relight “a dud.”
• Store fireworks in a cool, dry place away from children and pets.
• Never use fireworks around pets, keep pets indoors. Exposure to lit fireworks can potentially result in severe burns or trauma, and many pets are also fearful of loud noises and can become lost, scared or disoriented.

WATER SAFETY If your holiday plans include fun in the water, make sure every member of your family is water smart ─ has swimming skills and knows how to help others in an emergency.

• Everyone should learn to swim. Classes are available for both children and adults.
• Prevent unsupervised access to water. Always designate a “water watcher” to keep a close, constant eye on everyone in and around the water until the next water watcher takes over.
• Avoid distractions when supervising children. If a child is missing, check the water first. Drowning behavior is typically fast and silent. Unless rescued, a drowning person will last only 20 to 60 seconds before submerging.
• Reach or throw, don’t go! In the event of an emergency, reach or throw an object out to the person in trouble and tell them to grab on. Don’t go in! You could become a victim yourself. Without putting yourself in danger, rescue and remove the person from the water. Have someone call 911 if needed.”

American Red Cross (Have a Safe 4th of July)