“Gaucher disease can affect anyone, occurring in up to 1 in 40,000 live births in the general population.

Gaucher disease is more common among Jewish people of Ashkenazi (Eastern European) descent, occurring in approximately 1 in 450 within this population. As many as 1 in 10 may carry the mutated gene responsible for Gaucher disease.

Gaucher (go-SHAY) disease is the result of a buildup of certain fatty substances in certain organs, particularly your spleen and liver. This causes these organs to enlarge and can affect their function.  The fatty substances also can build up in bone tissue, weakening the bone and increasing the risk of fractures.  If the bone marrow is affected, it can interfere with your blood’s ability to clot.  An enzyme that breaks down these fatty substances doesn’t work properly in people with Gaucher disease.  Treatment often includes enzyme replacement therapy.”

National Gaucher Foundation (https://www.mayoclinic.org/diseases-conditions/gauchers-disease/symptoms-causes/syc-20355546)


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