“Hospital admissions for asthma traditionally peak during periods of particularly cold weather. This can be due to breathing cold air into the lungs, which can in turn trigger asthma, as well as picking up colds and flu.
Cher Piddock, a nurse for Asthma UK
This season to many feeling like in the North Pole finally ends in about a month or less but this winter has worsened or increased illnesses due to the freezing cold temperatures we have had and still do. Some health problems have been enhanced by the freezing temperatures like the common cold with even adding a sore throat trickling on to an attack of asthma Well here’s how to help your body deal with cold weather ailments.
“It’s your own immune response that makes you feel ill,” says Professor Ron Eccles of the Common Cold Centre in Cardiff, where experts have researched the common cold for more than 20 years.
When you get a cold, the virus attacks the nose and the back of the throat, and it doesn’t take long for the body’s natural defences to start to work.
“The immune system detects the virus and floods the area with white blood cells and chemical messengers, and these trigger various symptoms such as headaches and a blocked nose.”
“Women have more colds than men, and this is probably due to increased interaction with children,” says Professor Eccles. Children get around seven to ten colds a year, compared with two to three for adults. So people who spend a lot of time with children, such as childminders, nursery teachers or school teachers, are more likely to pick up the viruses.
“During a cold, the lining of your nose is the battlefront,” says Professor Eccles. When your nose feels blocked, it isn’t because it’s full of mucus, but because the blood vessels in your nose are inflamed.
The nasal lining is made from erectile tissue (similar to the tissue in the sexual organs). When you have a cold, the blood vessels swell up as infection-fighting white blood cells flood to the area. This narrows the air passage in your nose and restricts the airflow as you breathe.
A decongestant spray can reduce the swelling and allow you to breathe more easily.
The cold is not unusual if a sore throat comes along with it also. They are common in winter and are almost always caused by viral infections. There’s some evidence that changes in temperature, such as going from a warm, centrally heated room to the icy outdoors, can also affect the throat.
Cold air is a major trigger of asthma symptoms such as wheezing and shortness of breath. People with asthma should be especially careful in winter. Key steps in helping prevent the asthma attack to occur:
Continue to be careful in this winter weather and stay healthy at your optimal level. in dealing with this freezing cold.
Heredity is seen minimal with epilepsy. Lets take the general population. “The general population has about a 1% risk of developing epilepsy. Meanwhile, children of mothers with epilepsy have a 3 to 9% risk of inheriting this disease, while children of fathers have a 1.5 to 3% risk of inheritence.” Based on genes research
Dr. Robert S. Fischer Ph D. Stanford Epilepsy Center http://neurology.stanford.edu/epilepsy/patientcare/videos
There is the epilepsy that is diagnosed with a IDIOPATHIC cause – meaning unknown cause and the patient could grow out of it in childhood depending on the type of seizure disorder or not–in where the condition becomes chronic (for life).
Although heredity has been known since antiquity to cause epilepsy, the progress to date in identifying the genetic basis of epilepsy has been limited primarily to the discovery of single gene mutations that cause epilepsy in relatively rare families. For the more common types of epilepsy, heredity plays a subtler role, and it is thought that a combination of mutations in multiple genes likely determine an individual’s susceptibility to seizures, as well as the responsiveness to antiepileptic medications.
Epilepsy can be caused by genetic factors (inherited) or acquired (a etiology—cause) , although in most cases it arises in part from both. The neurology and neurological sciences of Stanford Epilepsy Center Dr. Robert S. Fischer Ph D. presents in the article Genetic Causes of Epilepsy.
He also presents in this article our genes are the instruction set for building the human body. Genes reside on chromosomes.
Going to the basics is every person has 46 chromosomes, carrying a total of about 30,000 genes. We get half our chromosomes from our mother and half from our father. While genes determine the structure of our body, they also control the excitability of our brain cells. Defective genes can make hyperexcitable brain cells, which are prone to seizures.
In recent years, several epilepsy conditions have been linked to mutations in genes, but the matter is complicated by the fact that different genes may be involved in different circumstances.
In general, the most common epilepsy conditions, including partial seizures, seem to be more acquired than genetic.
Gene testing will soon be able to identify predispositions to epilepsy, allowing doctors to help a patient get treatment and to assist with family counseling. One day, doctors may simply be able to swap a patient’s cheek, test his or her genes, and predict response to various epilepsy medicines, eliminating much of the trial and error in medication choice that goes on today. Eventually, we may even be able to repair or replace defective genes that predispose a person to epilepsy, a process called gene therapy.
Lastly, Dr. Robert Fischer Ph D presented in his article, that I found very interesting, the general population has about a 1% risk of developing epilepsy. Meanwhile, children of mothers with epilepsy have a 3 to 9% risk of inheriting this disease, while children of fathers have a 1.5 to 3% risk of inheritence. Still, the actual risk is upon the specific type of epilepsy. For example, partial seizures are less likely to run in families than are generalized seizures. In any event, with the usual forms of epilepsy, even if a parent does have the condition, there is more than a 90% chance that their child will not. So most epilepsies are acquired than inherited.
Clearly, genes determine a great deal of who we are, including our possible risk for epilepsy but slim versus a actual cause. But what happens to us in life and what we do is still the larger part of the risk for epilepsy.
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A person given this diagnosis in the 1970’s, or before and even up to the early 1990’s was quiet about ever letting people know about this since in the 1970’s and back with lack of knowledge, information to the public and definitely technology than versus now. Epilepsy is much more an accepted disease in the overall community compared to 20-25 years ago and back. Heck in the 1970’s and back these patients when having a seizure episode were characterized as “Freaks”. This was due to ignorance and lack of information but due to the past 20 to 25 years with the computer used more as a must in our lives with media, television and even our government they all have made it possible for society everywhere in the world to learn and understand diseases with acceptance in wanting to help those, particularly the US, but we still need a healthier America. It will take time to get there with the many multicultural lives that all live in the U.S. which practice differently on how important or where a healthy diet with exercise balanced with rest and stress well controlled is on their priority list in living.
For a person diagnosed with or without a cause of epilepsy these steps in learning about the disease with higher technology and continuous research with medications over the years has allowed them to be able to live a completely healthy life doing the same things other people do without the disease but only if the patient is UNDER COMPLETE CONTROL which includes being COMPLIANT; this does exist in America.
Compliant meaning taking their medications everyday as ordered by their neurologist with yearly or sooner follow-up visits with blood levels of the anti-seizure medications there on. This is the only way one with chronic epilepsy is guaranteed that living this way MAY stop the seizures from occurring (inactive epilepsy you can call it — meaning you’ll always have the disease but can put the seizure activity in a remission by medications preventing the seizure.)
The purpose for (follow up) F/U visits is for the neurologist to see how good of a therapeutic drug level your anti-seizure med is in (you get the blood test before the F/U visit). Possible do a EEG (electroencephalogram); the only test to decipher if you have spikes in your brain waves indicating you had a seizure (a 26 lead to wires on the brain, which is painless). Go to the expert for keeping you on the right track. Its just like based on the principle why a person gets a check up on there car by seeing the mechanic (the car’s doctor).
Types of seizures whether with a etiology or unknown:
I-Partial seizures (seizures beginning local)
1-simple partial seizures-(the person is conscious and not impaired). With motor symptoms, autonomic symptoms and even psychic symptoms.
2.)-Complex partial seizures-(the person is with impairment of consciousness)
II-Generalized seizures-(bilaterally symmetrical and without local onset).
3.) Tonic clonic seizures – Grand Mal
Took make your life one without seizures occurring putting your life on HOLD you need to TAKE CARE OF YOURSELF! That is all up to you the patient diagnosed with it.
Seizures that occur in individuals with developmental disabilities may be particularly difficult to diagnose. Always carry medical identification. If an emergency happens, knowledge of your seizure disorder can help the people around you keep you safe and provide the appropriate treatment.
WEB MD & KENNEDY KRIEGER INSTITUTE
When the seizure occurs there is a decrease in oxygen since the brain isn’t capable to send messages during the seizure. If the seizure continues to repeat one right after another the person is in status epilepticus and if the seizures do not stop the person can lead to a neuronal death; like John Travolta’s son who died of this for example.
The term seizure disorder may refer to any number of conditions that result in such a paroxysmal electrical discharge. These conditions could be metabolic or structural in nature.
For example, if metabolic this could be “Canavan disease” which is primarily a disease of demyelination. Your myelin sheath that protects and insulates the nerves is being destroyed and can cause a seizure as one of the symptoms.
*Another example being metabolic is thought to be caused by brain acetate deficiency resulting from a defect of N–acetylaspartic acid (NAA) catabolism (meaning breakdown is occurring). Accumulation of NAA, a compound thought to be responsible for maintaining cerebral fluid balance, can lead to cerebral edema and neurological injury, like a seizure as one symptoms of the disease.
*A structural condition to cause a seizure could be a tumor in the brain. Than there is just idiopathic, unknown cause for the epilepsy which if starts in childhood can resolve by the child growing out it, like in petite mal seizures but it not it goes into motor/focal or grand mal that is permanent the individual needs Rx for life.
Remember, etiology (the cause) of Epilepsy can be generally a sign of underlying pathology involving the brain–knowing the cause. To find this out diagnostic tooling be a neurologist who specializes in epilepsy is the best resource to go to. The epilepsy may be the first sign of a nervous system disease (ex. Brain tumor), or it may be a sign of a systemic or metabolic derangement. Where the treatment may be able to resolve the seizure symptom completely where this wasn’t a seizure disorder or epilepsy but just a symptom due to another disorder that may be 100% cured, like a operable tumor removed surgically from the brain.
Metabolic and Systemic Causes of Seizures:
a.) Electrolyte Imbalance=In the blood having acidosis, heavy metal poisoning, Hypocalcemia (low Ca+) , Hypocapnea (low carbon dioxide), Hypoglycemia (low glucose), Hypoxia (low oxygen), Sodium-Potassium imbalance, and than Systemic diseases (liver, renal failure, etc…). Then their is also toxemia of pregnancy, and water intoxication.
b.) Infections like meningitis, encephalitis, brain abcess.
c.) Withdrawal of sedative-hypnotic drugs=Alcohol, Antiepileptic drugs, Barbiturates, Benzodiazepines.
d.) Iatrogenic drug overdose=Theopylline, Penicillin.
Other causes of epilepsy can be Trauma, Heredity.
Structural causes of epilepsy:
Head trauma/Degenerative Disease like Alzheimer’s or Creutfeldz-Jacob or Huntington’s Chorea or Multiple Sclerosis or Pick’s Disease. There is also tumors or genetic disease or Stroke or Infections or Febrile seizures.
“A tumor is an abnormal growth of cells that serves no purpose. A benign tumor is not a malignant tumor, which is cancer.”
Web MD
Differences between tumors are as follows:
Benign Tumors ones are the following:
Encapsulating (the big answer to resolution of a tumor like this is this a tumor that is surgical to remove or can radiation or chemo decrease the size of it to nothing).
Non metastasizing-meaning it hasn’t spread anywhere.
Well – Differentiated-meaning easy to detect.
Slow – growing (just what is says)
Malignant Tumors ones are the following:
Invasive,Metastasizing,FrequentlyUndifferentiated,OftenRapidGrowing.
Know that carcinogenesis is the process of inducing a malignant tumor in an animal or human. Much of the research in carcinogenesis resolves around deoxyribonucleic acid (DNA), the influence of carcinogens on DNA, and the genes that are involved in differentiation (of this growth vs normal tissue of the body) and control of cancerous cell growth.
There is viral and chemical carcinogenesis. Both RNA and DNA viruses have been identified as causing natural and experimental tumors. Research has shown herpes viruses are DNA viruses. For almost every herpes group there is some experimental or epidemiological evidence linking it to human malignancy. Example Epstein-Barr viruse has been associated with Burkitt’s Lymphoma in West African children and nasopharyngeal cancer among Asian populations. Herpes simplex virus-1 has been linked to oral cancer and herpes simplex virus-2 to cervical cancer. All herpes viruses share a characteristic ability to remain latent within the body over long periods. Although they may be found throughout the body, CMV (cytomegaloviruse) infections are frequently associated with the salivary glands in humans and other mammals. Other CMV viruses are found in several mammal species, but species isolated from animals differ from HCMV in terms of genomic structure, and have not been reported to cause human disease.
The RNA viruses, also called oncoviruses or retroviruses induce leukemia, lymphoma, and mammary tumors in animals. To complete their natural cycle, these viruses must manufacture a viral DNA that is then integrated into the host cell DNA. To do this they produce an enzyme and the enzyme is able to use RNA as a template to produce DNA. Since these viruses can remain latent in a cell for long periods of time, it is only by identifying the enzyme or the viral DNA that scientists are able to detect cells infected with these viruses. This enzyme has been identified in some human leukemia and lymphoma cells.
In addition, approximately 20 oncogenes have been identified with these RNA viruses and some of these oncogenes have also been detected in human bladder cancer cells, Burkitt’s lymphoma, and promyelocytic leukemia.
There is also radiation carginogenesis. There is external radiation; take Leukemia which was the first cancer related to radiation exposure that was seen in the atomic bomb survivors. Within 6-8 years after the bomb, the incidence rates of leukemia increased to levels well above those seen in the Japanese population who were not exposed. The peak was highest from 1950 to 1952, at which time the incidence was 116:100,000, as compared with 3-4:100,000 to the unexposed population.
Internal Emitters – One of the most famous classics is that of the luminescent instrument – dial painters. The paint was used to create luminescent faces on watches and clocks containing radium. While painting, the workers licked the brushes and thus ingested the radium. Radium, when ingested is deposited in bone and tends to remain there.) Among this group, bone cancer or osteogenic sarcoma, a rare tumor, became prevalent. With this type of knowledge it led to limitations on surface testing of atomic weapons. Atomic weapons contain radioactive compounds that can become deposited in the bone.
Ultraviolet radiation or the Sunlight – One of the most obiquitous forms of radiation that every person is exposed to is the sunlight. Ultraviolet rays do not penetrate deeply. Most statistics on cancer do not include skin cancer due to it being treatable (the easiest cancer to treat on average). Another more dangerous type of cancer is melanoma that has been linked to sunlight exposure.
Tumor classification shows because the study of tissues originates with the study of their development in the embryo, the class of the tumor is often based on the tissues from which the tumor is derived.
Grading the cancer, besides classifying the tumor according to the tissue origin the pathologist will classify it looking at other characteris- tics. This aspect is Grading the cancer from level 1 or 2 or 3 or 4. If cells of classification in the tumor look like the mature cells of the tissue than the tumor is well differentiated=Grade 1. This type of tumor generally has a better prognosis compared to a tumor that is poorly differentiated or does not resemble the tissue from which it originated. Sometimes a poorly differentiated tumor is called anaplastic. An anaplastic tumor would have the highest grade of 4. Remember even though tow tumors might be similarly classified and have identical grades, in two different individuals the tumors might act differently. Because each patient is unique, has a different history, different immune responses, and different reserves, similar tumors might act very differently.
DIAGNOSIS
A definitive diagnosis of cancer can only be made after an examination of tissue obtained from a surgical procedure or biopsy. Biopsies can be excisional, meaning the whole lesion is removed, or incisional in which only part of the presumptive tumor is removed. Specimens can also be obtained from a needle biopsy. In this a core of tissue is drawn up in a needle. Cytological examination of exfoliated cells, as done in a pap smear, can lead to a presumptive diagnosis of cancer but often a surgical biopsy will be performed to confirm the diagnosis. Often the patient undergoes many other diagnostic tooling procedures besides the biopsy in the attempt to determine the nature and extent of the illness=from blood tests, diagnostic x-ray studies, and endoscopic procedures. These tests with the biopsy done are used to evaluate the extent of the disease in the patient. This process of determining the extent of tumor in an individual is called staging.
Treatment
Cancer treatment can be surgery, chemo or radiation or even all 3.
“About half of all men and one-third of all women in the US will develop cancer during their lifetimes. Today, millions of people are living with cancer or have had cancer. The risk of developing many types of cancer can be reduced by changes in a person’s lifestyle, for example, by staying away from tobacco, limiting time in the sun, being physically active, and eating healthy.”
AMERICAN CANCER SOCIETY
Cancer can be a simple disease or a monster to the body and let us first start reviewing the basics of cancer to understand this sentence.
The body is made up of trillions of living cells. Normal body cells grow, divide to make new cells, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow.
After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries.
The pathophysiological responses of a patient with cancer are frequently determined by the size and extent of the tumor and by the presence or absence of metastases.
Cancer starts when cells in a part of the body start to grow out of control. Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells cannot do. Growing out of control and invading other tissues are what makes a cell a cancer cell. Cells become cancer cells because of DNA (deoxyribonucleic acid) damage.
DNA is in every cell and it directs all its actions. In a normal cell, when DNA is damaged the cell either repairs the damage or the cell dies. In cancer cells, the damaged DNA is not repaired, but the cell doesn’t die like it should. Instead, the cell goes on making new cells that the body doesn’t need. These new cells all have the same damaged DNA as the first abnormal cell does=cancer cells.
The normal cells of a human body=Our red blood cells (our iron and cells that provide nutrition to our tissues by feeding oxygen to all our tissues), our white blood cells (fight infection off our body-part of immunity system), and our platelets (controls our clotting of the blood) all are taken over by the cancer cells especially if the cancer is primarily in the bone or metastasized to the bone since this organ in the human body produces all our blood cells in the bone marrow and the cancer in that causes the bone marrow to make cancer cells which is hard to cure especially if your cancer in the bone is at grade 3 or 4. If a patient’s cancer is grade 1 or 2 its much easier to treat to possible completely cure.
Again cancer can be a simple disease or a monster.
People can inherit abnormal DNA (it’s passed on from their parents), but most often the DNA damage is caused by mistakes that happen while the normal cell is reproducing or by something in the environment. Sometimes the cause of the DNA damage may be something obvious like cigarette smoking or sun exposure. But it’s rare to know exactly what caused any one person’s cancer. In most cases, the cancer cells form a tumor.
Some cancers, like leukemia, rarely form tumors. Instead, these cancer cells involve the blood and blood-forming organs and circulate through other tissues where they grow. Neoplasms or “new growths” are relatively autonomous (independent). This means that the growth and its behavior are more or less independent of the host (the normal body functions).
Neoplasms have been defined as benign or malignant; cancer is a common synonym used to refer to a malignant neoplasm. The difference between a benign and malignant neoplasm depends on its behavior in the host. Now if the neoplasm stays localized, enlarges slowly, is homogeneous in appearance, and can be resected or removed, then it is benign.
On the other hand, if the neoplasm spreads or metastasizes to other areas of the body, infiltrates and causes the destruction of normal tissue, left untreated, will kill the host, then the neoplasm is considered malignant (it takes over in the body).
If a large tumor is occupying the oral cavity, then the patients will have problems with ingestion that might lead to an altered immune-responsiveness.
If the tumor is in the large colon, then obstruction of the lumen, changes in bowel habits, and GI bleeding can occur.
In addition, if tumors are large they often outgrow the blood supply, which leads to necrosis and bleeding.
However, all the above changes are relatively late signs; the tumor would be quite large for a patient to exhibit these effects. Most small tumors are painless and symptomless.
In one sense this is unfortunate. If small tumors were painful, perhaps more patients would seek earlier treatment and tumors could be treated more successful being diagnosed before they are large.