“The HF Stats 2025: Heart Failure Epidemiology and Outcomes Statistics provides an update to past HF Stats reports and reveals that the lifetime risk of HF has increased to 24%, while the cost of this debilitating condition in the United States continues to soar.

Heart failure (HF) was a contributing cause in 425,147 deaths, accounting for 45% of cardiovascular deaths in the U.S. in 2022. HF mortality rates have been increasing since 2012, with a more pronounced acceleration in 2020-2021. The age-adjusted HF mortality rates were higher in 2021 than in 1999, highlighting an urgent need for improved HF prevention, implementation of guideline-directed therapies, and further research.

Black, American Indian, and Alaska Native individuals have the highest all-cause age-adjusted HF mortality rates compared with other racial and ethnic groups. From 2010 to 2020, HF mortality rates increased for Black individuals at a rate higher than any other racial or ethnic group, particularly for individuals below the age of 65.

Approximately 6.7 million Americans over 20 years of age have HF, and the prevalence is expected to rise to 8.7 million in 2030, 10.3 million in 2040, and 11.4 million by 2050.

The lifetime risk of HF has increased to 24%; approximately 1 in 4 individuals will develop HF in their lifetime. ”

Heart Failure Society of America -HFSA (Heart Failure Society of America (HFSA) Scientific Statement: Update on Device Based Therapies in Heart Failure)