“Moebius syndrome was originally described by German ophthalmologist Alfred Graefe in 1880, but is named for German neurologist Paul Julius Moebius, who reported features of this condition in 1888.
The incidence of Moebius syndrome is roughly 2 to 20 cases per million births. The condition occurs in all ethnicities. There is no gender bias (males and females are affected equally). At present, the etiology of Moebius syndrome is currently poorly understood, but may be due to genetic and/or environmental factors.
In very rare cases, a change in specific genes may be causative of Moebius syndrome. Additionally, there are several other separate conditions with similarities to Moebius syndrome that have identified genetic etiologies.”
MOEBIUS syndrome foundation (https://moebiussyndrome.org)