“Studies suggest that up to 50 percent of patients with depression experience problems with anger and irritability (Fava et al., 2010; Kovess-Masfety et al., 2013). However, the prevalence may well be higher, as many patients are inhibited about experiencing or expressing angry feelings toward others (Busch, 2009). Anger can exacerbate depression in several ways; for example, irritability can lead to disruptions in relationships, causing increased feelings of loss and isolation. Additionally, anger can be directed toward the self, leading to intense self-criticism and guilt (Abraham, 1911; Busch et al., 2016; Freud, 1917).”

Psychology Today (Anger and Depression: Addressing the Links Between Them | Psychology Today)