“Leukemia is a broad term for cancers of the blood cells. The type of leukemia depends on the type of blood cell that becomes cancer and whether it grows quickly or slowly. Leukemia occurs most often in adults older than 55, but it is also the most common cancer in children younger than 15.  There is Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia , Chronic Myelogenous Leukemia, Hairy Cell Leukemia, Childhood Acute Lymphoblastic Leukemia, and Childhood Acute Myeloid Leukemia.”

National Cancer Institute (https://www.cancer.gov/types/leukemia#: ~:text=Leukemia%20is%20a%20broad%20term,in%20children%20younger%20than%2015.)

“Chronic pain is pain that lasts for over three months. You may feel the pain all the time or it may come and go. It can happen anywhere in your body and has countless causes.

Chronic pain is a very common condition and one of the most common reasons why people seek medical care. In 2021, about 20.9% of U.S. adults (51.6 million people) experienced chronic pain, according to a study from the U.S. Centers for Disease Control and Prevention (CDC).

Pain is your body’s way of telling you that something’s wrong, like an alarm. But when that alarm continues to go off for months or years, it can drown out many aspects of life that bring you joy. And it can take quite a toll on your physical, mental and emotional health. Because of this, it’s essential to seek help for chronic pain. Together, you and your healthcare provider can develop a plan to help dampen chronic pain.”.

Cleveland Clinic (https://my.clevelandclinic.org/health/diseases/4798-chronic-pain)

In most instances, painful sensations arise from tissue injury in the body. Sensitive nerve endings pick up pain signals and carry these messages along nerves to the spinal cord and then onto the brain. All along these complex pathways, there are biological “gates” that can be either opened or closed. When these gates are closed, pain is reduced or eliminated. When open, pain messages continue through the circuit. It is when these gates are jammed open that chronic pain cycles begin.

As you recall, acute pain is short lived and serves as a warning signal. When you fix whatever is wrong, the pain usually goes away. In the case of chronic pain, pain does not necessarily signal that the body is undergoing more damage. Most chronic pain is caused by a malfunction of the nervous system, either in nerves or the brain. The malfunction or opening of the pain gates causes and endless barrage of pain signals to cycle. Chronic pain then becomes a disease itself, taking on a life of its own.

How can we close the gates of pain?

The gates are affected by several factors, most importantly by the pattern of nerve impulses which reach the spinal cord from the rest of the body, and nerve impulses coming from the brain. Sometimes the nerve impulses traveling through the spinal gates can be affected by other forms of physical stimulation. Giving your nervous system a competing source of input can fool the nervous system and alter your perception of pain.

There are many ways to accomplish this. You may have noticed that rubbing or massaging a painful area may have relieved your pain in the past. Applying electrical stimulation (e.g. TENS), applying heat or cold, acupuncture, or nerve blocks may also provide a competing source of input. It is also important to realize that certain mental activities or thoughts taking place in the brain can help to close the spinal gates.

Another way we can work to close the gates of pain is to affect the release of several chemicals that help pain signals travel to the brain. Neurotransmitters are biochemical messengers that carry pain signals from one nerve cell to the next. The three main neurotransmitters that send pain signals to the brain are substance P, NMDA (n-methyl-d-aspartate), and glutamate. Excess amounts of these chemicals, especially substance P, make it easier for pain signals to reach the brain.

Therefore, another way of stopping pain involves manipulating pain provoking neurotransmitters. This can be accomplished by prescription or over the counter medications, acupuncture, injections, hypnosis, or biofeedback.:

The role of the Endorphins:

The endorphins are another class of chemicals which are produced in the brain and serve an important role in the pain experience. These chemical are naturally occurring pain relieving substances, similar to morphine or other opiates, produced in the body. Endorphins work on special receptor sites in the brain. They act as keys which unlock receptors thus generating nerve impulses to shut down pain. Morphine and other opiates have similar chemical structures which turn off pain.
Several situations or conditions raise endorphin levels in the brain thus reducing pain. They include thinking with a positive attitude, happiness, and regular exercise.

The Role of Stress:

It is natural to connect a physical stress to the body, such a broken arm, to the perception of pain. The role of psychological stress may not seem as obvious. The brain structures involved in stress can affect the production of key hormones in the body, suppress the body’s immune system, and activate the autonomic nervous. These are the same biological changes that may occur from physical stresses on the body-the body may not differentiate between physical and psychological stress. The net effects of these changes on the body are to lower our internal resistance to pain, thus further encouraging the chronic pain cycle.

Many sources of stress feed into the chronic pain cycle. First off, as you would expect, pain itself is stressful. Pain sensations are perceived as undesirable and are at very least annoying. Pain creates tension, both physical and emotional. Physical tension may show itself as muscle tension or affect the cardiovascular, gastrointestinal, or immune systems. Emotional tension may reveal itself as anger, frustration, worry, depression, or frustration. Both physical and emotional tension, initially set in motion by pain, worsen pain. Thus the vicious cycle of pain is begins-pain leads to tension and tension leads to more pain.

A second source of stress comes from all the negative consequences that occur as a result of a chronic pain condition. Chronic pain may create difficulties with family relationships, social or recreation activities, self-esteem, and employment.

Yet another source of stress arises from the hardships that can be encountered from the stresses of everyday living. Everything from difficulties putting on your shoes in the morning to difficulties standing long enough to go grocery shopping are added on top of pain-related stressors. In the end, an individual not only suffers from chronic pain, but from chronic stress.

The consequences of chronic stress:

Whatever the type of stress, either physical or psychological, the outcome on pain is to worsen it. Chronic stress also may result in other physical ailments such as tension headaches, muscle spasms, gastrointestinal problems, and elevated blood pressure. It can also lead to fatigue, depression, and a sense of hopelessness.

The key is how to prevent chronic pain:

Chronic pain can’t always be prevented But rememeber if you have pain go to a MD to help you get to your optimal level of function and hopes you get to PAIN FREE.

1-  ONE is staying in good physical and mental health may be the best way to prevent it or help you cope with it.
2-  Treat your health problems early.
3- Get enough sleep every night. Learn to alternate activity with rest throughout each day.
4- Exercise.
5- Eat a balanced diet.

Try to reduce stress in your life.

“Prostate cancer is cancer that occurs in the prostate. The prostate is a small walnut-shaped gland in males that produces the seminal fluid that nourishes and transports sperm.

Prostate cancer is one of the most common types of cancer. Many prostate cancers grow slowly and are confined to the prostate gland, where they may not cause serious harm. However, while some types of prostate cancer grow slowly and may need minimal or even no treatment, other types are aggressive and can spread quickly.

Prostate cancer that’s detected early — when it’s still confined to the prostate gland — has the best chance for successful treatment.”

MAYO CLINIC (https://www.mayoclinic.org/diseases-conditions/prostate-cancer/symptoms-causes/syc-20353087)

“Treatment for ovarian cancer usually involves a combination of surgery and chemotherapy.

• Surgery: An operation in which doctors cut out the cancer.
• Chemotherapy: Use of special medicines to shrink or kill the cancer. The drugs can be pills you take or medicines given in your veins, or sometimes both.
• Targeted therapy: Use of drugs to block the growth and spread of cancer cells. The drugs can be pills you take or medicines given in your veins. You will get tests to see if targeted therapy is right for your cancer type before this treatment is used.

Visit the National Cancer Institute for more information about ovarian cancer treatment.”

Center for Disease Control and Prevention – CDC (https://www.cdc.gov/ovarian-cancer/treatment/?cid=google:paid_search_co:ik_24:q1_24_rsa_refresh:ovarian&gad_source=1&gclid=EAIaIQobChMIj63WtM3HiAMVAU9HAR3BciZCEAAYASAAEgKu-_D_BwE)

“Ovarian cancer is a type of cancer that begins in the female reproductive organs that produce and store eggs (ovaries). It occurs when abnormal ovarian cells divide and multiply uncontrollably. “Ovarian cancer” is a generic term for any primary malignant ovarian tumor. However, ovarian cancer is not one disease. There are many types of ovarian cancer, including some that are extremely rare and require specialized treatment. Therefore, establishing the correct diagnosis upfront is very important. The main types of ovarian cancer are named for the cells where the disease first forms. There is epithelial ovarian cancer, germ cell ovarian cancer, stromal ovarian cancer, and primary peritoneal ovarian. ”

MD Anderson Cancer Center

Through an accurate reference the Centers for Disease Control and Prevention, who wants to save lives and protect people, support the following:

Smoking is estimated to increase the risk—

• • For coronary heart disease by 2 to 4 times^1,6
  • For stroke by 2 to 4 times¹
  • Of men developing lung cancer by 25 times¹
  • Of women developing lung cancer by 25.7 times¹

Smoking causes diminished overall heath, such as self-reported poor health, increased absenteeism from work, and increased health care utilization and cost.

Smokers are at greater risk for diseases that affect the engine of the body=The heart and its branches=The circulatory system (putting a smoker at high risk for cardiovascular disease).

• Smoking causes stroke and coronary heart disease—the leading causes of death in the United States.
• Even people who smoke fewer than five cigarettes a day can have early signs of cardiovascular disease.
• Smoking damages blood vessels and can make them thicken and grow narrower. This makes your heart beat faster and your blood pressure go up. Clots can also form.
• A heart attack occurs when a clot blocks the blood flow to your heart. When this happens, your heart cannot get enough oxygen causing starvation of food, being oxygen to the heart tissue. This damages the heart muscle, and part of the heart muscle can die, which is what exactly happens with a heart attack where angina (lack of 02 is reversible).
• A stroke occurs when a clot blocks the blood flow to part of your brain or when a blood vessel in or around your brain bursts causing again starvation of food, being 02, just in a different tissue part. Get it oxygen is the food to all our tissues of the body
• Blockages caused by smoking can also reduce blood flow to your skin and legs (For example Peripheral Vascular Disease= PVD). Ever see the commercial with a person telling you to stop smoking with fingers surgically removed or limbs, PVD is what occurred to that individual and the person didn’t stop smoking. Due to this behavior what happened the vessels of the individual’s limbs became so narrowed that it cut off oxygenated blood supply to those tissue parts causing ischemia-lack of oxygen, which led to necrosis of the tissue (death) and the part had to be surgi-cally removed. Now that individual can’t walk or grasp things with those limbs that were operated on. Is smoking worth this consequence? I don’t think so, what about you? Just think about it if you still smoke.Smoking can cause lung disease by damaging your airways and the small air sacs (alveoli) found in your lungs. What actually happens to the lung tissue is the pin point openings (alveoli) keeps expanding to a wider opening. The alveoli is responsible of oxygen and carbon dioxide exchange when we inhale and exhale but with the alveoli stretched the exchange of the gases gets poor.
• Smoking effects the transmission of the body=The Lungs

• Lung diseases caused by smoking include COPD, which includes emphysema (especially) and chronic bronchitis.
• Cigarette smoking causes most cases of lung cancer.
• If you have asthma, tobacco smoke can trigger an attack or make an attack worse.^1,2
• Smokers are 12 to 13 times more likely to die from COPD than nonsmokers.

Smoking can cause cancer in almost every area of the body. If nobody smoked, one of every three cancer deaths in the United States would not happen. Smoking increases risk of dying from cancer and other diseases in cancer patients and survivors.

For those who quit smoking what risks you reduce:

• Quitting smoking cuts cardiovascular risks. Just 1 year after quitting smoking, your risk for a heart attack drops sharply.²
• Within 2 to 5 years after quitting smoking, your risk for stroke could fall to about the same as a nonsmoker’s.²
• If you quit smoking, your risks for cancers of the mouth, throat, esophagus, and bladder drop by half within 5 years.²
• Ten years after you quit smoking, your risk for lung cancer drops by half.

Again, if you smoke you may want to consider stopping; give it a thought.

“One in 5 children in the United States are obese. Childhood obesity puts kids at risk for health problems that were once seen only in adults, like type 2 diabetes, high blood pressure, and heart disease.  The good news? Childhood obesity can be prevented. Take action during National Childhood Obesity Awareness Month!  You can encourage communities, health professionals, and families to work together to raise awareness about the obesity epidemic and show people how to work towards a solution.  By raising awareness about childhood obesity, we can all work together to keep our kids healthy.”

U.S. Department of Health and Human Services – Health.org (https://health.gov/news/news-and-announcements/2018/09/toolkit-national-childhood-obesity-awareness-month)

“When we are born, our arteries are clear and healthy. They carry blood, oxygen, and nutrients from our hearts to every part of our bodies. They are the channels of life.

  VS

Modifiable Risk Factors putting you at risk for high cholesterol that can put you at risk for heart disease are:

High B/P, Diabetes, Low HDL=good cholesterol, High LDL=bad cholesterol, smoking, eating foods high in SATURATED FAT & CHOLESTEROL, harmful use of alcohol, and lack of any activity in your life (your regular routine doesn’t count like work unless your in a job severely active like construction building homes for example 5 days or week or a personal work out trainer 4 to 5 days week).

MAYO CLINIC states Factors Increasing your BAD Cholesterol:

• Poor diet. Eating saturated fat, found in animal products, and trans fats, found in some commercially baked cookies and crackers and microwave popcorn, can raise your cholesterol level. Foods that are high in cholesterol, such as red meat and full-fat dairy products, will also increase your cholesterol.
• Obesity.
• Lack of exercise. Exercise helps boost your body’s HDL, or “good,” cholesterol while increasing the size of the particles that make up your LDL, or “bad,” cholesterol, which makes it less harmful.
• Smoking.
• Age. Because your body’s chemistry changes as you age, your risk of high cholesterol climbs. For instance, as you age, your liver becomes less able to remove LDL cholesterol.
• Diabetes. High blood sugar contributes to higher levels of a dangerous cholesterol called very-low-density lipoprotein (VLDL) and lower HDL cholesterol. High blood sugar also damages the lining of your arteries.

Non-modifiable Risk Factors=4 types only which are factors we can’t control:

1-Heredity (The higher the risk is when the heredity is closer to you in your family tree=Nuclear family–mom, dad, and siblings).

2-Age (Men aged 45y/o or older & Women aged 55 y/o or older)

3-Gender (It may affect your risk, for years heart disease was considered a man’s disease but we now know that heart disease is the leading cause of death for women as well as men. Although men tend to develop coronary artery disease earlier in life, after age 65 the risk of heart disease for both genders is equal.)

4-Race (Heart disease is higher among African Americans, Mexican Americans, American Indians, native Hawaiians, and some Asian Americans compared to Caucasians).

WHAT DOES ALL THIS MEAN?  To make this short & simple, from continuous high cholesterol over time, especially with history in your nuclear family puts you at risk for ATHERO-SCLEROSIS = Blockage In Arteries.  This puts at you at risk for a heart attack, stroke (Based on oxygen blocked by high cholesterol causing lack of oxygenated blood (nutrients) to the heart or brain due to high cholesterol build up in arteries supplying the heart and brain.  This is a high risk for MI & CVA).

Now it makes sense?  The answer to prevention or treatment of cardiac disease is changing or modifying your diet, if it’s unhealthy 100% or just partially. The answer includes exercise (from just walking or if you like working out, even better) and if needed medication but your doctor will decide. All these changes can modify your blood lipid profile=cholesterol control, which helps increasing your heart to a better tolerance with activity, stress and simply functioning. Recommended is going to a cardiologist for people diagnosed with heart conditions or your general practitioner with any illness/disease before making changes to help guide you towards the right choices. Your doctor can help you in determining which prevention or treatment plan is best for you.

Foods high in cholesterol=Fast foods, whole fat dairy products-milk/cheese/butter/mayonnaise/ bacon/processed deli meats/salad dressings and shortenings.

The key is to be living a healthy life. This consists of diet, exercise or activity and healthy habits learned and practiced routinely in your life that will help prevent or assist in treating cardiac disease. The better we treat ourselves regarding health the higher the odds we will live a longer   life. There is not just one food to eat or one type of exercise to do or one healthy habit to keep you healthy, there are choices. Wouldn’t you want less disease/illness for yourself and for others throughout the nation including the future generations?  It is all in change and that would be in your diet, activity getting increased and exercise balanced with rest.  Most importantly sticking to it regularly not doing these changes on occasion and that is all in how well you discipline yourself.

FOR MORE INFORMATION:

National Heart Lung and Blood Institute

P.O. Box 30105

Bethesda, MD 20824-0105