“Results from national-level surveys and data systems are used to identify male/female differences in mortality rates, prevalence of diseases, physical functioning, and indicators of physiological status. Male/female differences in health outcomes depend on epidemiological and social circumstances and behaviors, and many are not consistent across historical time and between countries. In all countries, male life expectancy is now lower than female life expectancy, but this was not true in the past. In most countries, women have more problems performing instrumental activities of daily living, and men do better in measured performance of functioning. Men tend to have more cardiovascular diseases; women, more inflammatory-related diseases. Sex differences in major cardiovascular risk factors vary between countries—men tend to have more hypertension; women, more raised lipids. Indicators of physiological dysregulation indicate greater inflammatory activity for women and generally higher cardiovascular risk for men, although women have higher or similar cardiovascular risk in some markers depending on the historical time and country.”

NIH National Library of Medicine (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345642/)

“Most cataracts develop slowly and don’t disturb your eyesight early on. But with time, cataracts will eventually interfere with your vision.

At first, stronger lighting and eyeglasses can help you deal with cataracts. But if impaired vision interferes with your usual activities, you might need cataract surgery. Fortunately, cataract surgery is generally a safe, effective procedure.”

MAYO CLINIC (https://www.mayoclinic.org/diseases-conditions/cataracts/symptoms-causes/syc-20353790)

“Regarding risk factors, anyone can get cataracts. While most people don’t typically show symptoms until at least the age of 40, cataracts can also affect young adults or even children. Heredity, disease, eye injury and smoking could cause cataracts to develop at an earlier age.”

Specialty Eye Institute by midwest vision partners (https://www.specialtyeyeinstitute.com/june-is-cataract-awareness-month/)

“Alzheimer’s is the most common cause of dementia, a general term for memory loss and other cognitive abilities serious enough to interfere with daily life. Alzheimer’s disease accounts for 60-80% of dementia cases.  Alzheimer’s worsens over time. Alzheimer’s is a progressive disease, where dementia symptoms gradually worsen over a number of years.  Alzheimer’s has no cure, but two treatments — aducanumab (Aduhelm™) and lecanemab (Leqembi™) — demonstrate that removing beta-amyloid, one of the hallmarks of Alzheimer’s disease, from the brain reduces cognitive and functional decline in people living with early Alzheimer’s. Other treatments can temporarily slow the worsening of dementia symptoms and improve quality of life for those with Alzheimer’s and their caregivers. Today, there is a worldwide effort underway to find better ways to treat the disease, delay its onset and prevent it from developing.  Just like the rest of our bodies, our brains change as we age. Most of us eventually notice some slowed thinking and occasional problems with remembering certain things. However, serious memory loss, confusion and other major changes in the way our minds work may be a sign that brain cells are failing.”

Alzheimer’s Association (https://www.alz.org/alzheimers-dementia/what-is-alzheimers)

“Alzheimer’s disease (AD), the most generic form of dementia, is an irreversible, progressive brain disorder that destroys neuronal cells. AD is the fifth leading cause of death for people aged sixty-five and older [1]. Scientists do not yet fully understand the cause of this disease, which is likely to involve several factors and can affect each person differently. Health care providers often fail to diagnose AD at an early stage; thus, researchers are currently working on a diagnostic framework in which AD onset can be detected based on biological changes in the brain and body even before any symptoms appear [2]. Early AD identification remains challenging as the conventional biomarkers for AD can overlap with the classical aging process.

Recent studies suggest that dysfunctional glucose metabolism is often found in AD brains. An aged-matched comparison between regular and AD brains showed reduced glucose utilization, evidenced in APP (AD model) mice [7]. Thus, glucose utilization could be an early important imaging marker for AD detection. Under normal physiological conditions, brain cells use a relatively higher percentage of glucose for their function and energy source [8]. Alteration in cerebral glucose metabolic rate and glucose consumption are reflected in the synaptic excitability and neuronal activity [9]. In the AD brain, a lesser extent of glucose utilization was detected by positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) as a tracer [10]. Specifically, a reduction in glucose consumption at the hippocampal and posterior cingulate of the brain was observed in the early AD stages [11,12,13].

NIH National Library of Medicine (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455726/)

“To diagnose Alzheimer’s dementia, doctors conduct tests to assess memory impairment and other thinking skills, judge functional abilities, and identify behavior changes. They also perform a series of tests to rule out other possible causes of impairment.  Alzheimer’s dementia can be diagnosed in several different ways. Often, Alzheimer’s is diagnosed through a doctor’s exam. They will evaluate your signs and symptoms and do several tests. They may talk to friends and family members to find out more about symptoms and behavior.

It’s important to get an accurate diagnosis of Alzheimer’s, the most common type of dementia. The correct diagnosis is an important first step toward getting the appropriate treatment, care, family education and plans for the future.”.

MAYO CLINIC (https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/in-depth/alzheimers/art-20048075)

“Alzheimer’s disease is a type of brain disease, just as coronary artery disease is a type of heart disease. It is
caused by damage to nerve cells (neurons) in the brain. The brain’s neurons are essential to thinking, walking,
talking and all human activity.  In Alzheimer’s, the neurons damaged first are those in parts of the brain responsible for memory, language and thinking. As a result, the first symptoms tend to be memory,
language and thinking problems. Although these symptoms are new to the individual affected, the brain changes that cause them are thought to begin 20 years or more before symptoms start.”.

Alzheimer’s Association (https://www.alz.org › alzheimers-facts-and-figures)

“The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have a form of lupus!  Lupus strikes mostly women of childbearing age. Ninety percent (90%) of people living with lupus are women. However, men, children, and teenagers develop lupus, too. Most people with lupus develop the disease between the ages of 15-44. Most people with lupus develop the disease between the ages of 15-44.  Lupus is two to three times more prevalent among African American, Hispanic/Latina, Asian American, Native American, Alaska Native, Native Hawaiian and other Pacific Islander women than among White women.”.

Lupus Foundation of America (https://www.lupus.org/resources/lupus-facts-and-statistics)

“World Lupus Day was 5/10/23 and by WELCOA a health topic for May. Genes do play a role in the predisposition to the development of lupus. There are dozens of known genetic variants linked to lupus. These genes impact both who gets lupus and how severe it is.  20 percent of people with lupus will have a parent or sibling who already has lupus or may develop lupus. About 5 percent of the children born to individuals with lupus will develop the illness.  Although lupus can develop in people with no family history of lupus, there are likely to be other autoimmune diseases in some family members.  Lupus is not contagious, not even through sexual contact. You cannot “catch” lupus from someone or “give” lupus to someone.

World Lupus Day (https://worldlupusday.org/lupus-facts-and-statistics/)

“You can’t cure or slow the progression of Huntington disease, but health care providers can offer medications to help with certain symptoms.   As Huntington disease progresses, you will need constant assistance and supervision because of the debilitating nature of the disease. People usually die from the disease within 15 to 20 years of developing symptoms.  If you have been diagnosed with, or are at risk for Huntington disease, it is critical to maintain your physical fitness as best you can. People who exercise regularly and stay active tend to do better than those who don’t.  A number of studies are currently under way to examine possible therapies for Huntington disease.”

John Hopkins Hospital (https://www.hopkinsmedicine.org/health/conditions-and-diseases/huntingtons-disease)