“When too much cortisol is present in the body, it is called Cushing’s syndrome, regardless of the cause.  it is called Cushing’s syndrome, regardless of the cause. Cortisol is made by the adrenal glands which are stimulated by ACTH, which is produced in pituitary gland. When the cause of the excess cortisol is excess ACTH made by a pituitary tumor, the condition is called “Cushing’s disease. “

Harvard Medical School