“Both hodgkin and non-hodgkin lymphoma are malignancies of a family of white blood cells known as leukocytes, which help the body fight off infections and other diseases/illnesses.”

Dana-Farber Cancer Institute

A particular cell known as the Reed-Sternberg cell is found in the biopsies. This cell is not usually found in other lymphomas, therefore they are called non Hodgkins lymphoma. This may not seem a very big difference, but it is important because the treatment for Hodgkins and non Hodgkins lymphomas can be very different.

Although the diseases may sound similar, there is a lot of difference between Hodgkin and non-Hodgkin lymphoma.

Both Hodgkin and non-Hodgkin lymphoma are malignancies of a family of white blood cells known as lymphocytes, which help the body fight off infections and other diseases.

Both Hodgkin’s lymphoma and non-Hodgkin’s lymphoma are lymphomas — a type of cancer that begins in a subset of white blood cells and these are called lymphocytes. Lymphocytes are an integral part of your immune system, which protects you from germs.

The main difference between Hodgkin’s lymphoma and non-Hodgkin’s lymphoma is in the specific lymphocyte each involves but also it includes:

Sources: National Cancer Institute and Lymphoma Research Foundation 2016

Hodgkin lymphoma is marked by the presence of Reed-Sternberg cells, which are mature B cells that have become malignant, are unusually large, and carry more than one nucleus. The first sign of the disease is often the appearance of enlarged lymph nodes. Non-Hodgkin lymphoma, by contrast, can be derived from B cells or T cells and can arise in the lymph nodes as well as other organs. (B cells and T cells play different roles in the body’s immune response to disease.)

In 2017 by the Mayo Clinic it states both diseases are relatively rare, but non-Hodgkin lymphoma is more common in the United States, with more than 70,000 new cases diagnosed each year, compared to about 8,000 for Hodgkin lymphoma. The median age of patients with non-Hodgkin lymphoma is 60, but it occurs in all age groups. Hodgkin lymphoma most often occurs in people ages 15 to 24 and in people over 60. There are more than 60 distinct types of non-Hodgkin lymphoma, whereas Hodgkin lymphoma is a more homogeneous disease.

The two forms of lymphoma are marked by a painless swelling of the lymph nodes. Hodgkin lymphomas are more likely to arise in the upper portion of the body (the neck, underarms, or chest). Non-Hodgkin lymphoma can arise in lymph nodes throughout the body, but can also arise in normal organs. Patients with either type can have symptoms such as weight loss, fevers, and night sweats.

The diseases often follow different courses of progression. Hodgkin lymphoma tends to progress in an orderly fashion, moving from one group of lymph nodes to the next, and is often diagnosed before it reaches an advanced stage. Most patients with non-Hodgkin lymphoma are diagnosed at a more advanced stage.

Treatments for lymphoma vary depending on the type of disease, its aggressiveness, and location, along with the age and general health of the patient. As a general rule, however, Hodgkin lymphoma is considered one of the most treatable cancers, with more than 90 percent of patients surviving more than five years. Survival rates for patients with non-Hodgkin lymphoma tend to be lower, but for certain types of the disease, the survival rates are similar to those of patients with Hodgkin lymphoma.

A doctor can tell the difference between Hodgkin’s lymphoma and non-Hodgkin’s lymphoma by examining the cancer cells under a microscope. If in examining the cells, the doctor detects the presence of a specific type of abnormal cell called a Reed-Sternberg cell, the lymphoma is classified as Hodgkin’s. If the Reed-Sternberg cell is not present, the lymphoma is classified as non-Hodgkin’s.

Many subtypes of lymphoma exist, and your doctor will use laboratory tests to examine a sample of your lymphoma cells to determine your specific subtype. Expect to wait a few days to receive results from these specialized tests.

Your type of lymphoma helps your doctor determine your prognosis and your treatment options. The types of lymphoma have very different disease courses and treatment choices, so an accurate diagnosis is an integral part of getting the care you need.

How both Hodgkin’s and Non-Hodgkin’s Disease are diagnosed:

• Physical exam. Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as for a swollen spleen or liver.
• Blood and urine tests. Blood and urine tests may help rule out an infection or other disease.  A sample of your blood is examined in a lab to see if anything in your blood indicates the possibility of cancer (in both of these diseases particularly the WBCs).
• Imaging tests. Your doctor may recommend imaging tests to look for tumors in your body. Tests may include X-ray, CT, MRI and positron emission tomography (PET).
• Lymph node test. Your doctor may recommend a lymph node biopsy procedure to remove all or part of a lymph node for laboratory testing. Analyzing lymph node tissue in a lab may reveal whether you have non-Hodgkin’s lymphoma and, if so, which type.  Your doctor may recommend a lymph node biopsy procedure to remove a lymph node for laboratory testing. He or she will diagnose classical Hodgkin’s lymphoma if abnormal cells called Reed-Sternberg cells are found within the lymph node.
• Bone marrow test. A bone marrow biopsy and aspiration procedure involves inserting a needle into your hipbone to remove a sample of bone marrow. The sample is analyzed to look for non-Hodgkin’s lymphoma cells to look for non-Hodgkin’s lymphoma cells or to look for non-Hodgkin’s lymphoma cells.  This test is done on numerous types of cancer patients in helping to diagnose the cancer they have.

Treatments for both Hodgkin’s Lymphoma & Non-Hodgkin’s Lymphoma:

First the doctor needs to know what stage of cancer your in ranging from I to IV.  This shows the doctor the following information to help the M.D. decide what treatment would be most effective to take.

• Stage I. The cancer is limited to one lymph node region or a group of nearby nodes or limited to a single organ.
• Stage II. In this stage, the cancer is in two lymph node regions, or the cancer has invaded one organ and the nearby lymph nodes as well. But the cancer is still limited to a section of the body either above or below the diaphragm.
• Stage III. When the cancer moves to lymph nodes both above and below the diaphragm, it’s considered stage III. Cancer may also be found in the lymph nodes above the diaphragm and in the spleen in non-Hodgkins and may also be in one portion of tissue or an organ near the lymph node groups or in the spleen in Hodgkins.
• Stage IV. This is the most advanced stage of non-Hodgkin’s and Hodgkin’s lymphoma. Cancer cells are in several portions of one or more organs and tissues.
• Stage III. When the cancer moves to lymph nodes both above and below the diaphragm, it’s considered stage III. Cancer may also be in one portion of tissue or an organ near the lymph node groups or in the spleen.
• Stage IV. This is the most advanced stage of Hodgkin’s lymphoma. Cancer cells are in several portions of one or more organs and tissues. Stage IV in both lymphomas affects not only the lymph nodes but also other parts of the body, such as the liver, lungs or bones.
  

Hodgkin Lymphoma Consultation

Which Hodgkin’s lymphoma treatments are right for you depends on the type and stage of your disease, your overall health, and your preferences. The goal of treatment is to destroy as many cancer cells as possible and bring the disease into remission.

Chemotherapy

Chemotherapy is a drug treatment that uses chemicals to kill lymphoma cells. Chemotherapy drugs travel through your bloodstream and can reach nearly all areas of your body.

Chemotherapy is often combined with radiation therapy in people with early-stage classical type Hodgkin’s lymphoma. Radiation therapy is typically done after chemotherapy. In advanced Hodgkin’s lymphoma, chemotherapy may be used alone or combined with radiation therapy.

Chemotherapy drugs can be taken in pill form or through a vein in your arm, or sometimes both methods of administration are used. Several combinations of chemotherapy drugs are used to treat Hodgkin’s lymphoma.

Side effects of chemotherapy depend on the drugs you’re given. Common side effects are nausea and hair loss. Serious long-term complications can occur, such as heart damage, lung damage, fertility problems and other cancers, such as leukemia.

Radiation therapy

Radiation therapy uses high-energy beams, such as X-rays and protons, to kill cancer cells. For classical Hodgkin’s lymphoma, radiation therapy is often used after chemotherapy. People with early-stage nodular lymphocyte-predominant Hodgkin’s lymphoma may undergo radiation therapy alone.

During radiation therapy, you lie on a table and a large machine moves around you, directing the energy beams to specific points on your body. Radiation can be aimed at affected lymph nodes and the nearby area of nodes where the disease might progress. The length of radiation treatment varies, depending on the stage of the disease. A typical treatment plan might have you going to the hospital or clinic five days a week for several weeks. At each visit, you undergo a 30-minute radiation treatment.

Radiation therapy can cause skin redness and hair loss at the site where the radiation is aimed. Many people experience fatigue during radiation therapy. More-serious risks include heart disease, stroke, thyroid problems, infertility and other cancers, such as breast or lung cancer.

Bone marrow transplant

Bone marrow transplant, also known as stem cell transplant, is a treatment to replace your diseased bone marrow with healthy stem cells that help you grow new bone marrow. A bone marrow transplant may be an option if Hodgkin’s lymphoma returns despite treatment.

During a bone marrow transplant, your own blood stem cells are removed, frozen and stored for later use. Next you receive high-dose chemotherapy and radiation therapy to destroy cancerous cells in your body. Finally your stem cells are thawed and injected into your body through your veins. The stem cells help build healthy bone marrow.

People who undergo bone marrow transplant may be at increased risk of infection.

Other drug therapy

Other drugs used to treat Hodgkin’s lymphoma include targeted drugs that focus on specific vulnerabilities in your cancer cells and immunotherapy that works to activate your own immune system to kill the lymphoma cells. If other treatments haven’t helped or if your Hodgkin’s lymphoma returns, your lymphoma cells may be analyzed in a laboratory to look for genetic mutations. Your doctor may recommend treatment with a drug that targets the particular mutations present in your lymphoma cells.

Targeted therapy is an active area of cancer research. New targeted therapy drugs are being studied in clinical trials.

Now look at Non-Hodgkin’s Lymphoma Treatment and look at the similarities of Hodkin’s Lymphoma Rx; both are WBC’s Blood Cancers:

If your non-Hodgkin’s lymphoma is aggressive or causes signs and symptoms, your doctor may recommend treatment. Options may include:

Chemotherapy

Chemotherapy is a drug treatment — given orally or by injection — that kills cancer cells. Chemotherapy drugs can be given alone, in combination with other chemotherapy drugs or combined with other treatments.

Side effects of chemotherapy depend on the drugs you’re given. Common side effects are nausea and hair loss. Serious long-term complications can occur, such as heart damage, lung damage, fertility problems and other cancers, such as leukemia.

Radiation therapy

Radiation therapy uses high-powered energy beams, such as X-rays and protons, to kill cancer cells. During radiation therapy, you’re positioned on a table and a large machine directs radiation at precise points on your body. Radiation therapy can be used alone or in combination with other cancer treatments.

During radiation therapy, you lie on a table and a large machine moves around you, directing the energy beams to specific points on your body. Radiation can be aimed at affected lymph nodes and the nearby area of nodes where the disease might progress. The length of radiation treatment varies, depending on the stage of the disease. A typical treatment plan might have you going to the hospital or clinic five days a week for several weeks, where you undergo a 30-minute radiation treatment at each visit.

Radiation therapy can cause skin redness and hair loss at the site where the radiation is aimed. Many people experience fatigue during radiation therapy. More-serious risks include heart disease, stroke, thyroid problems, infertility, and other cancers, such as breast or lung cancer.

Bone marrow transplant

Bone marrow transplant, also known as a stem cell transplant, involves using high doses of chemotherapy and radiation to suppress your bone marrow. Then healthy bone marrow stem cells from your body or from a donor are infused into your blood where they travel to your bones and rebuild your bone marrow.

People who undergo bone marrow transplant may be at increased risk of infection.

Other drug therapy

Biological therapy drugs help your body’s immune system fight cancer.

For example, one biological therapy called rituximab (Rituxan) is a type of monoclonal antibody that attaches to B cells and makes them more visible to the immune system, which can then attack. Rituximab lowers the number of B cells, including your healthy B cells, but your body produces new healthy B cells to replace these. The cancerous B cells are less likely to recur.

Also, a drug called ibrutinib (Imbruvica) has been approved by the Food and Drug Administration (FDA) for some people undergoing treatment for non-Hodgkin’s lymphoma.

Radioimmunotherapy drugs are made of monoclonal antibodies that carry radioactive isotopes. This allows the antibody to attach to cancer cells and deliver radiation directly to the cells. An example of a radioimmunotherapy drug used to treat non-Hodgkin’s lymphoma is ibritumomab tiuxetan (Zevalin).

Clinical trials

Clinical research studies (clinical trials) may be an option for people whose disease has not been controlled by other treatment options. Ask your doctor about possible clinical trials for your type of non-Hodgkin’s lymphoma.

“More than 102 million American Adults (20 years or older) have total cholesterol levels at or above 200 mg/dL, which is above healthy levels. More than 35 million of these people have levels of 240 mg/dL or higher, which puts them at high risk for heart disease. Cholesterol is a waxy, fat-like substance found in your body and many foods. Your body needs cholesterol to function normally and makes all that you need. Too much cholesterol can build up in your arteries. After a while, these deposits narrow your arteries, putting you at risk for heart disease and stroke.”

Centers for Disease Prevention and Control

“When you sit, you use less energy than you do when you stand or move. Research has linked sitting for long periods of time with a number of health concerns. They include obesity and a cluster of conditions — increased blood pressure, high blood sugar, excess body fat around the waist and abnormal cholesterol levels — that make up metabolic syndrome. Too much sitting overall and prolonged periods of sitting also seem to increase the risk of death from cardiovascular disease and cancer.”

MAYO CLINIC Dr. Edward R. Laskowski

Humans are not sedentary creatures.

It is only logical that the human body was not created to sit still for many hours during the day. Research has proven that how much we sit has serious consequences for our weight, our posture, and even on our lifespan. Human beings did not start out with the lifestyle that most people in the western world now have. We lived on our feet, and not on our bottoms. Now that we have desk jobs, televisions, transport, and computers, most humans spend more time sitting on our bottoms the we spend sleeping. Our bodies were not meant to sit that much. In fact, sitting for more than 6 hours a day makes you 40% likelier to die within 50 years than someone who sits less than 3 hours a day. Even if you exercise regularly.

Hard to admit, but easy to believe: eight in 10 Americans spend nearly every single minute of their workday sitting behind a desk, according to research published in the journal PLOS One. Yikes.

But “the problems are not with sitting itself, but with passively sitting,” says Mark Schneider, a personal trainer at Movement Minneapolis. “Sitting is easy. If it took effort, fewer people would do it. Because of its ease, it’s common to do it to excess — and anything done to excess will be detrimental.”

As a result, people are burning around 120 to 140 fewer calories per workday than they did in 1960, resulting in a slow creep of weight gain. (This could tally up to about a nine-pound-a-year margin you’ll need to burn off.) Even scarier than the scale impact? The health impact. By sitting all day, you’re subjecting your body to a whole lot of bad.

1. You Can Say Goodbye to Good Cholesterol After Just 2 Hours of Sitting

Just like a light switch, electrical activity flips off the moment your butt hits the chair. “Calorie burning is significantly reduced and lipoprotein lipase, an enzyme that assists with the breakdown of fat, dramatically and rapidly drops,” says Dominique Wakefield, a Michigan-based health and fitness expert for the American Council on Exercise (ACE). That enzyme also plays a role in changing low-density lipoprotein (bad cholesterol) to high-density lipoprotein (good cholesterol). Sitting for eight or more hours a day — a pretty standard amount of time for people who work desk jobs! — decreases the enzyme’s ability to convert bad to good by 95 percent, scientists at The Ohio State University have found.

2. Your Muscles Will Ache — Like, All the Time

Tune in to how you’re sitting as you read this paragraph. Wait! Don’t move a muscle quite yet. Just sit still. Ask yourself: How does the seat feel? How is your head angled and where are your feet placed? How do the arm rests impact your arm alignment?

“The lack of attention to these things is what causes the problem. Sitting well, so it has minimal negative effects on you, is a skill. And like any skill it will take some effort to learn, but eventually will become habitual,” Schneider says.

Be mindful of your posture and adjust alignment as needed, says Jessica Matthews, a personal training expert for ACE who’s based in San Diego. “While standing, your ear, shoulder, hip, knee and ankle should form a straight line with the spine in an ‘S’ shape, due to its natural curvature. This also applies while in a seated position, except that the ear, shoulder, and hip should align, and the knee and ankle should align.”

Until you master pro-level sitting, expect tight hip muscles, increased back and neck pain, and possible breathing difficulties, since the rounded shoulder, tucked chin posture decreases the ability of your ribs to expand, Schneider says.

3. You’re 2 ½ Times More Likely to Struggle With Obesity

As mentioned above, while sitting, your calorie-burning potential crawls slower than the wait for the next season of Game of Thrones. In fact, ACE reports you’re more than twice as likely to be obese if you sit for six hours per day compared to just 30 minutes per day. Surprisingly, sitting too much is twice as dangerous for your wellbeing as being obese, says a study published in The American Journal of Clinical Nutrition.

4. Your Risk for Cancer, Type 2 Diabetes, and Cardiovascular Disease Will Climb

Beyond making you gain extra pounds, being too stationary can do a number on your longevity. “Sitting increases risk of death up to 40 percent. Inactivity is killing people and is arguably one of this generation’s greatest health threats,” Wakefield says. Cancer, diabetes and cardiovascular disease risks are more stark when overall physical activity levels are low, too, according to a review in the Annals of Internal Medicine.

5. Your Overall Mortality Risk Jumps

Nearly four percent of all deaths can be traced back to sitting too much, says a study in the American Journal of Preventative Medicine. ACE adds a surprising stat: Sitting less than three hours a day can add two years to your life. On the flip side, sitting for more than six hours and racking up a limited amount of exercise can raise overall risk of death by 94 percent.

“Multiple myeloma is a cancer of plasma cells. Normal plasma cells are found in the bone marrow and are an important part of the immune system.”

American Cancer Society

“Most cancers are solid—a collection of mutated cells that grow out of control and form a tumor. The six most common cancers—breast, lung, prostate, colorectal, melanoma and bladder—are solid cancers that account for almost 1 million new cases a year. Cancers that are not considered solid cancers are often lumped together in the category of blood cancers: leukemia, lymphoma and myeloma.”

Cancer Treatments of America (www.cancercenter.com)

Lets just start with our type of cells in the body first that would help us better understand these names in their meaning and understand what gets effected immediately when types of cells are not in normal levels.

We have red blood cells in our blood stream and abbreviated RBCs.  Their substance in them are rich in hemoglobin, an iron-containing bio-molecule.  They are also known as erythrocytes.  They also are the food carrier of oxygen (02) carried in our body from tissue to tissue.  This is done via the heart by its pumping action.  RBCs are sent throughout the bloodstream from our heart.  In time sent back to the heart when all the 02 is used up by the tissues it reached.  Then sent to the lungs from the right side of the heart to get more 02 rich supply in the cell.  The lungs take from the cell the carbon dioxide (a toxin from the cell) that we release via exhaling from the lungs.  The cell  goes to the left side of the heart pumping the RBCs back out in the blood stream to release this 02 (energy)to our tissues to stay alive repeating this cycle over andl over again. till that RBC dies.  Without 02 to our tissues means death.

We have white blood cells.  White blood cells (also called leukocytes for WBCs in general and abbreviated as WBCs) are the cells of the immune system that are involved in protecting the body, they fight infection.

White blood cells (leukocytes) are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders but their are types of WBCs. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system (lymph nodes).

Types of white blood cells

• Monocytes. They have a longer lifespan than many white blood cells and help to break down bacteria.

• Lymphocytes. They create antibodies to defend against bacteria, viruses, and other potentially harmful invaders.

• Neutrophils. They kill and digest bacteria and fungi. They are the most numerous type of white blood cell and your first line of defense when infection strikes.

• Basophils. These small cells appear to sound an alarm when infectious agents invade your blood. They secrete chemicals such as histamine, a marker of allergic disease, that help control the body’s immune response.

• Eosinophils. They attack and kill parasites, destroy cancer cells, and help with allergic responses.

Both red blood and white blood cells have what is called a nucleus inside them meaning it stores the cell’s hereditary material, or DNA, and it coordinates the cell’s activities, which include growth, intermediary metabolism, protein synthesis, and reproduction (cell division).  In addition, cancer cells often have an abnormal shape, both of the cell, and of the nucleus (the “brain” of the cell.) The nucleus appears both larger and darker than normal cells. The reason for the darkness is that the nucleus of cancer cells contains excess DNA.

Platelet cells (also called thrombocytes are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.  The main function of platelets is to contribute to hemostasis: the process of stopping bleeding at the site in the body anywhere.  Platelets are considered “not a true cell” because of its make up and doesn’t have a nucleus in it like RBCs or WBCs.

Where do all our cells derive from?  The bone marrow, in adult humans bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. On average, bone marrow constitutes 4% of the total body mass of humans.

In the bone marrow the formation of blood cellular components happens. All cellular blood components are derived from haematopoietic stem cells.  The formation of blood cellular components.

When these cells get affected with being increased or decreased in the bloodstream especially changing make up of the cell (Ex. cancer cell) then the person is at risk for problems that can occur if not resolved in the near future.

Multiple myeloma, lymphoma, and leukemia

These are all types of cancers that effect your WBCs and immunity system. Doctors often call them blood cancers.  The cells that are effected are WBC’s and after the cancer cells start intially effecting WBC’s affects the other cells.

­While these three types of cancers are alike in some ways (all three deals with intially affecting WBCs and our immune system) but they affect different parts of your body. Some are harder to treat than others.

Multiple myeloma hits your plasma cells. Multiple myeloma is a cancer that forms in a type of white blood cell called a plasma cell.  These white blood cells make antibodies to fight disease. Myeloma cancer cells take over, and your body can’t fight infections like they did when your good WBCs where in normal level.  Remember all cancer cells keep replicating in the bone marrow (Where our cells are made from normally).

They take over eliminating the plasma normal cells allowing cancer cells to take over. In addition, cancer cells often have an abnormal shape, both of the cell, and of the nucleus (the “brain” of the cell.). The nucleus appears both larger and darker than normal cells nucleus (RBCs and WBCs). The reason for the darkness is that the nucleus of cancer cells contains excess DNA.

The cancer cells make abnormal antibodies that settle in your blood not allowing the regular function of regular plasma cells being done (fighting infection off).  Instead cancer cells do the opposite.  They can eat away at bone or damage your kidneys in this disease.

“The most common reason to have an induction is that the pregnancy has gone 2 or more weeks past the due date (or at the due date with twins). In this situation, the baby may: Get too large for a vaginal delivery Not receive enough oxygen through the placenta.  Other reasons could be Water breaks and contractions don’t begin,  High blood pressure or diabetes in the mother, Infection in the uterus, The baby is not growing properly, Low amniotic fluid level or Rh incompatibility.”

Winchester Hospital  (Winchester, Maine)

Why would I need to be induced?

Labor induction — also known as inducing labor — is the stimulation of uterine contractions during pregnancy before labor begins on its own to achieve a vaginal birth. Your health care provider might recommend inducing labor for various reasons, primarily when there’s concern for a mother’s health or a baby’s health. For example:

• You’re approaching two weeks beyond your due date, and labor hasn’t started naturally (postterm pregnancy)
• Your water has broken, but labor hasn’t begun (premature rupture of membranes)
• You have an infection in your uterus (chorioamnionitis)
• Your baby has stopped growing at the expected pace (fetal growth restriction)
• There’s not enough amniotic fluid surrounding the baby (oligohydramnios)
• You have diabetes
• You have a high blood pressure disorder
• Your placenta peels away from the inner wall of the uterus before delivery — either partially or completely (placental abruption)
• You have a medical condition such as kidney disease or obesity

Can I wait for labor to begin naturally?

Nature typically prepares the cervix for delivery in the most efficient, comfortable way. However, if your health care provider is concerned about your health or your baby’s health or your pregnancy continues two weeks past your due date, inducing labor might be the best option.

Why the concern after two weeks? When a pregnancy lasts longer than 42 weeks, amniotic fluid might begin to decrease and there’s an increased risk of having a baby significantly larger than average (fetal macrosomia). There’s also an increased risk of C-section, fetal inhalation of fecal waste (meconium aspiration) and stillbirth.

Can I request an elective induction?

Elective labor induction is the initiation of labor for convenience in a person with a term pregnancy who doesn’t medically need the intervention. For example, if you live far from the hospital or birthing center or you have a history of rapid deliveries, a scheduled induction might help you avoid an unattended delivery. In such cases, your health care provider will confirm that your baby’s gestational age is at least 39 weeks or older before induction to reduce the risk of health problems for your baby.

Can I do anything to trigger labor on my own?

Probably not.

Techniques such as exercising or having sex to induce labor aren’t backed by scientific evidence. Also, avoid herbal supplements, which could harm your baby.

What are the risks?

Labor induction isn’t for everyone. For example, it might not be an option if you have had a prior C-section with a classical incision or major uterine surgery, your placenta is blocking your cervix (placenta previa), or your baby is lying buttocks first (breech) or sideways (transverse lie) in your uterus.

Inducing labor also carries various risks, including:

• Failed induction. About 75 percent of first-time mothers who are induced will have a successful vaginal delivery. This means that about 25 percent of these women, who often start with an unripened cervix, might need a C-section. Your health care provider will discuss with you the possibility of a need for a C-section.
• Low heart rate. The medications used to induce labor — oxytocin or a prostaglandin — might cause abnormal or excessive contractions, which can diminish your baby’s oxygen supply and lower your baby’s heart rate.
• Infection. Some methods of labor induction, such as rupturing your membranes, might increase the risk of infection for both mother and baby.
• Uterine rupture. This is a rare but serious complication in which your uterus tears open along the scar line from a prior C-section or major uterine surgery. An emergency C-section is needed to prevent life-threatening complications. Your uterus might need to be removed.
• Bleeding after delivery. Labor induction increases the risk that your uterine muscles won’t properly contract after you give birth (uterine atony), which can lead to serious bleeding after delivery.

Inducing labor is a serious decision. Work with your health care provider to make the best choice for you and your baby