Archive | July 2023

QUOTE FOR TUESDAY:

“If you haven’t thought about whether or not the foods that you consume are truly nourishing you, take time to examine your eating habits to ensure that you’re meeting your nutritional goals.

“It’s unreasonable to expect you to eat healthy foods 100 percent of the time, but for better health, aim to eat nutritious foods at least 80 percent of the time. That means sweets, snacks and other junk food should only be occasional treats, rather than the bulk of your diet,” says Jason Sayanlar, M.D., FACC, a cardiologist at Hackensack University Medical Center.

The American Heart Association recommends that adults should limit their sodium intake to 1,500 mg per day, but the average person consumes more than twice that amount. Too much salt may lead to high blood pressure and increase the risk of heart disease.  To cut back on daily salt intake, eat fewer processed, pre-packaged foods, including canned foods and frozen meals. At mealtime, reach for the pepper mill instead of the salt shaker when you want more flavor. And in the supermarket, read labels and choose low-sodium soup, salt-free nuts and more.  Foods containing refined carbohydrates are stripped of fiber and other nutrients during the manufacturing process.  This strips you from good nutrients; pick whole-grain varieties of breads, pastas, rice, crackers, breakfast cereals and other foods.”.

Hackensack Meridian Health (https://www.hackensackmeridianhealth.org/en/healthu/2021/11/18/worst-foods-to-eat-for-your-health)

QUOTE FOR MONDAY:

It is now the standard of care in several countries for all pregnant women to be routinely tested for GBS with a vaginal/rectal swab test during the 36th or 37th week during each pregnancy unless their urine already cultured positive in the current pregnancyGBS colonization is transient which means that a woman could test negative, but be colonized later in pregnancy and vice versa.  GBS is a fast-acting type of bacteria so it is imperative that everyone who takes care of your baby knows the symptoms of possible GBS infection in babies and how to respond.  GBS is a leading cause of sepsis and meningitis in newborns according to the U.S Centers for Disease Control and Prevention (CDC).”.

Group B Strep International (https://www.groupbstrepinternational.org/july_gbs_awareness_month.html)

International Group B Strep Throat Awareness

 

Group B Streptococcus (GBS), or Streptococcus agalactiae, is a type of bacteria that is naturally found in the digestive and lower reproductive tracts of both men and women.  About 1 in 4 pregnant women “carry” or are “colonized” with GBS.

Carrying GBS does not mean that you are unclean.  Anyone can carry GBS. GBS is not considered to be a sexually transmitted disease or infection as it can occur on its own even in someone with no prior sexual experience. However, bacteria can be passed between sexual partners, including through oral contact.

The awareness month for group B strep is July. This is a common bacterium that affects adults and it does not present with any symptoms or signs. The pregnant women can pass these bacteria to their unborn children during the first few months after delivery or during child birth and this can be fatal. Most people who suffer from this bacterial infection are not aware of it and pregnant women get to know about it because of the screening that is done during prenatal visits. The screening tests is usually done during the third trimester and this test was started in the mid 1990s. Research indicates that since that time, the number of children who are affected by this infection has dropped from 1.7 to 0.28 in every 1000 births.

This month helps in raising awareness to women who are pregnant and those who are in the child rearing period to prevent Group B Strep infection. This helps women to keep their unborn babies healthy and safe as the infection can be fatal.

The National Charity that is associated with group B strep advices all pregnant women to be aware of this infection caused by streptococcus group B. This is the most common type of infection in new born babies as it causes meningitis, pneumonia and sepsis which can be fatal in the first few weeks of life. The bacterium is carried by women who do not present with any symptoms and therefore it can be easily passed to the baby during child birth.

The main message that is shared on this month awareness is that Group B Strep is fatal and that the infection can be prevented. People are taught on the need to go for testing as the bacterial colonization can be carried by people in the vagina or the lower intestines. Most people are carriers of this infection but they are not aware because they have never been tested for the same. This is because the infection does not present with any signs or symptoms. However, in some cases, the infection can get access into the blood stream and this can trigger fatal infections. When a pregnant woman gets this infection it can be spread to the unborn baby in the following ways:

While the baby is still in the womb, during a normal or a cesarean section birth, through the urinary tract or amniotic fluid, or through direct contact with the bacteria that is present in the birth canal.

The infants who are infected by this bacterium during birth are prone to infections and this includes meningitis, pneumonia and sepsis. The children who survive this infection are at risk of getting long term complications especially in cases where they suffered from meningitis. The common complications that can occur include cerebral palsy, hearing loss, mental and physical disabilities.

Pregnant women should be aware of the need for testing for each pregnancy and it does not matter whether they were tested for the previous pregnancies. This is because all pregnancies are different and it is vital to ensure that the baby is safe in all pregnancies.

 

QUOTE FOR THE WEEKEND:

“Your appendix is a thin tube in your lower right abdomen. It sits where your small intestine meets your large intestine.

Your appendix is a 4-inch-long tube. It’s attached to the first part of your large intestine. Its exact function is unclear. Some people believe that it’s an evolutionary holdover that provides no benefits to your health.

This conventional wisdom has led to the widespread use of appendectomies to prevent and treat disease.”

Healthline

The appendix of the human body & Appendicitis.

The appendix is a small pouch attached to the large intestine. The appendix is a small, finger-shaped pouch of intestinal tissue located between the small intestine (cecum) and large intestine (colon). The appendix is a small finger-shaped tube that branches off the first part of the large intestine.

Appendicitis (means append=appendix and itis=inflammation.  Appendicitis causes pain in your lower right abdomen. However, in most people, pain begins around the navel and then moves. As inflammation worsens, appendicitis pain typically increases and eventually becomes severe.

Although anyone can develop appendicitis, most often it occurs in people between the ages of 10 and 30. Standard treatment is surgical removal of the appendix.

Signs and symptoms of appendicitis may include:

  • Sudden pain that begins on the right side of the lower abdomen
  • Sudden pain that begins around your navel and often shifts to your lower right abdomen
  • Pain that worsens if you cough, walk or make other jarring movements
  • Nausea and vomiting
  • Loss of appetite
  • Low-grade fever that may worsen as the illness progresses
  • Constipation or diarrhea
  • Abdominal bloating
  • Flatulence

The site of your pain may vary, depending on your age and the position of your appendix. When you’re pregnant, the pain may seem to come from your upper abdomen because your appendix is higher during pregnancy.

Strongly suggestive of appendicitis is pushing down on the R lower quadrant and upon letting go the pain is severe compared to when pushing down.  It is called “rebound effect”.

Diagnostic Tests for confirming appendicitis:

  • Blood test. This allows your doctor to check for a high white blood cell count, which may indicate an infection.
  • Urine test. Your doctor may want you to have a urinalysis to make sure that a urinary tract infection or a kidney stone isn’t causing your pain.
  • Rectal exam
  • Imaging tests. Your doctor may also recommend an abdominal X-ray, an abdominal ultrasound, computerized tomography (CT) scan or magnetic resonance imaging (MRI) to help confirm appendicitis or find other causes for your pain.

Treatment:

Appendicitis treatment usually involves surgery to remove the inflamed appendix. Before surgery you may be given a dose of antibiotics to treat infection.  There are times though antibiotics may only be used and the MD see’s if the appendicitis is resolved; it depends on the MD and the severity of the appendicitis.

Surgery to remove the appendix (appendectomy)

Appendectomy can be performed as open surgery using one abdominal incision about 2 to 4 inches (5 to 10 centimeters) long (laparotomy). Or the surgery can be done through a few small abdominal incisions (laparoscopic surgery). During a laparoscopic appendectomy, the surgeon inserts special surgical tools and a video camera into your abdomen to remove your appendix.

In general, laparoscopic surgery allows you to recover faster and heal with less pain and scarring. It may be better for older adults and people with obesity.

But laparoscopic surgery isn’t appropriate for everyone. If your appendix has ruptured and infection has spread beyond the appendix or you have an abscess, you may need an open appendectomy, which allows your surgeon to clean the abdominal cavity.

Expect to spend one or two days in the hospital after your appendectomy.

Draining an abscess before appendix surgery

If your appendix has burst and an abscess has formed around it, the abscess may be drained by placing a tube through your skin into the abscess. Appendectomy can be performed several weeks later after controlling the infection.

 

QUOTE FOR FRIDAY:

“A risk factor is anything that affects your chance of getting a disease such as cancer.

The only way to prevent some soft tissue sarcomas is to avoid exposure to risk factors whenever possible. Still, most sarcomas develop in people with no known risk factors. At this time, there’s no known way to prevent this cancer.

Injury and lifestyle factors such as smoking, diet, and exercise are NOT linked to the risk for soft tissue sarcoma . But the injury issue has caused some confusion in the past. One reason is that an injured area might swell. That swelling could look like a tumor, but it isn’t one. Also, when you are injured, the pain may draw your attention to the injured area. A doctor may check the area, and x-rays or other imaging studies may be done. This can make it more likely that any sarcoma that’s there will be discovered, even though it may have been there for some time.

Still, scientists have found a few risk factors that make a person more likely to develop soft tissue sarcomas.”

American Cancer Society

 

Part II Sarcoma Awareness Month!

Soft tissue sarcoma symptoms:

Like many forms of cancer, soft tissue sarcoma symptoms may appear at a more advanced stage of the disease, or you might not notice any symptoms at all. Symptoms, if they are present, will also vary depending on the type of sarcoma and its location.

Signs of soft tissue sarcoma include:

A lump or mass is the most common soft tissue sarcoma sign. The lump will form in the area in which the tumor is growing, and it may be accompanied by some pain if it is pressing on a nerve or muscle. Even if the lump isn’t painful, if it continues to grow, or if it is located deep within an extremity or body cavity, consult your doctor.

Uncomfortable swelling is another sign of soft tissue sarcoma, especially when it is located in the arms and legs.

Limited mobility may be a symptom of soft tissue sarcoma. Some tumors can restrict motion, such as those found in the hip, knee, shoulder or hands.

Skin lesions can occur when a sarcoma tumor breaks through the skin.

Other symptoms may be signs of soft tissue sarcoma, because a sarcoma tumor can form almost anywhere in the body and can therefore affect a variety of organs. For example, sarcomas in the abdomen may cause abdominal pain, vomiting or constipation, while sarcomas in the uterus may cause vaginal bleeding and/or abdominal pain. With gastrointestinal stromal tumors (GISTs), you may feel full after eating only very small meals, or you may vomit blood or have dark bowel movements.

Diagnosing Sarcoma:

If your doctor thinks you may have a sarcoma, you’ll probably need a full exam and tests, including: A sample of cells from the tumor, called a biopsy. A plain x-ray to imaging tests, such as a CT scan, an ultrasound, an MRI, a PET (Positron Emission Tomography) to help see inside your body. A bone scan, if you might have osteosarcoma.  Also a biopsy-several types of biopsies are used to diagnose sarcomas..

Treatment of Soft Tissue Sarcoma:

Surgery is typically the primary treatment for soft-tissue sarcoma, used to remove tumors. Chemotherapy, radiation therapy and/or targeted therapy may also be recommended, either alone or in combination with surgery, depending on the stage and extent of the disease, along with other factors.

Surgery

The goal of surgery is to locate and completely remove the soft tissue sarcoma tumor. Our pathologists then examine the tumor to determine whether or not additional treatment is necessary, and to reduce the risk of recurrence.

Chemotherapy

Chemotherapy may be used in combination with surgery and radiation therapy to treat advanced-stage soft tissue sarcoma. Chemotherapy drugs work to either destroy cancer cells or impede their ability to grow and reproduce.

At our hospitals, we are developing innovative therapies personalized to the care of each soft tissue sarcoma patient. Our medical oncologists work closely with soft tissue sarcoma patients to determine if chemotherapy is an appropriate treatment option. Throughout your soft tissue sarcoma treatment, your care team continually monitors the effect of chemotherapy on the disease, with physical exams, blood tests, CT scans, MRI scans and chest X-rays and imaging.

Radiation therapy

Depending on the type of soft tissue sarcoma you have and the extent of the disease, your soft tissue sarcoma treatment plan may include radiation therapy. Though surgery is usually the main treatment approach for soft tissue sarcoma, radiation treatments may also be used before (neoadjuvant therapy) or following surgery (adjuvant therapy).

Targeted therapy

Unlike standard chemotherapy drugs, which may affect all cells in the body, targeted therapy drugs are designed to seek out and kill specific cancer cells while sparing surrounding healthy cells. Targeted cancer therapies may be used alone, in combination with other targeted therapy treatments or with other soft tissue sarcoma treatments, such as chemotherapy, radiation therapy and surgery. Among the drugs used in targeted therapy are so-called kinase inhibitors, which target specific protein receptors that help regulate cell growth.

 

QUOTE FOR THURSDAY:

“Sarcoma is a type of cancer that can occur in various locations in your body.

Sarcoma is the general term for a broad group of cancers that begin in the bones and in the soft (also called connective) tissues (soft tissue sarcoma). Soft tissue sarcoma forms in the tissues that connect, support and surround other body structures. This includes muscle, fat, blood vessels, nerves, tendons and the lining of your joints.

There are more than 70 types of sarcoma. Treatment for sarcoma varies depending on sarcoma type, location and other factors.”.

MAYO CLINIC

Part I Sarcoma Awareness Month!

What is Sarcoma?

Sarcoma is a rare but deadly form of cancer affecting connective tissues such as fat, muscle, blood vessels, nerve, bone, deep skin and cartilage. There are roughly 15,000 new cases in the United States each year, with a very low median age of 36 (for bone sarcomas). Survival rates are low, even in comparison to other rare cancers. Rhabdomyosarcoma, a relatively common sarcoma, has a five-year survival rate of 65%, even if caught before metastasis. If caught after metastasis, the five-year survival rate lowers to approximately 30%. This is all to say that while sarcomas are rare, they are extremely devastating.

Sarcomas are a diverse and sporadic group of tumors that have minimal hereditary influence. They are generally classified into two major groups; the group of tumor-specific reoccurring genetic mutations via specific and aberrant chromosome translocation, and the group of non-reoccurring mutations which are based on severe genetic and chromosomal instability. Both groups have altered cell growth-factor signaling pathways. As a result, the introduction of drugs which can normalize growth-factor receptors and proteins are of great interest and the primary treatment given. With improvements in these drugs, it is believed that sarcoma can move from a deadly disease to a chronic but non-life-threatening disease.

Unfortunately, the specificity of the first group of sarcomas, where specific chromosomes are improperly translocated, can often permit the sarcoma to prevail after standard treatment. This is obviously problematic but, if overcome, could spark the development of a whole new field of cancer treatment. In other words, if scientists can discover how to isolate and guide specific chromosomal arrangement, they will able to address many of the hard to treat cancers of today.

With genetic engineering it is theoretically possible to prevent cancer before it begins. However, even without moving this far into the future, the improper chromosomal translocation can provide a sort of name-tagging of the cancer cell. With the cancer cells identified, it can guide modalities aimed at destroying diseased tissue while sparing healthy tissue.

Sarcoma is an under-researched cancer whose research can help to elevate cancer treatment, as a whole. Not only would breakthroughs save the lives of countless children, it could also advance medicine, as a whole. By bringing awareness to sarcoma and the potential development its research can spark, this potential can become a reality.

Soft tissue sarcomas may develop in any tissue that connects, supports or surrounds other structures and organs in the body. Some examples of where soft tissues sarcomas can develop are muscles, fascia (the tough membrane that surrounds muscles), tendons, fat, blood vessels, nerves and synovial tissues (connective tissue that makes up the membranes surrounding joints).

Soft tissue sarcomas are rare in adults, accounting for less than 1 percent of all new cases of cancer. The American Cancer Society reports that about 12,750 new cases of soft tissue sarcoma will be diagnosed in 2019 (7,240 cases in males and 5,510 cases in females). Sarcomas can be found almost anywhere in the body.

According to the National Cancer Institute, about 50 percent of soft tissue sarcoma cases occur in the extremities (arms and legs), 40 percent occur in the trunk (back and chest), and 10 percent occur in the head and neck.

QUOTE FOR THE WEDNESDAY:

“Many people who have been burned in fires have also inhaled smoke. Sometimes people inhale smoke without sustaining skin burns.

Inhaling small amounts of smoke usually causes no serious, lasting effects. However, if the smoke contains certain poisonous chemicals or is unusually dense or if inhalation is prolonged, serious problems can develop. Even common household materials such as plastics and fabrics can produce poisonous chemicals (toxic products of combustion) when they burn.

Smoke inhalation can cause problems in several ways:  Suffocating the body with carbon monoxide,  Poisoning the body with toxic chemicals, Damaging the windpipe, breathing passages, and/or lungs from toxic chemicals,  Burning the mouth and throat from hot gases, Carbon monoxide is a gas produced in many fires. When inhaled, carbon monoxide prevents the blood from carrying oxygen so tissues do not get enough oxygen.”.

MERCK MANUAL